Minimal clinically important difference for asthma endpoints: an expert consensus report

Evolving phenotypes to endotypes: is precision medicine achievable in asthma?

(2020) Diego Bagnasco et al.   Expert Review of Respiratory Medicine

Exploring the relevance and extent of small airways dysfunction in asthma (ATLANTIS): baseline data from a prospective cohort study

(2019) Dirkje S Postma et al.   Lancet Respiratory Medicine

Biomarkers and asthma management

(2018) Levi B. Richards et al.   Current Opinion in Allergy and Clinical Immunology

Asthma

(2018) Alberto Papi et al.   LANCET

Periostin: The bone and beyond

(2017) L Idolazzi et al.   European Journal of Internal Medicine

Asthma Control and Sputum Eosinophils: A Longitudinal Study in Daily Practice

(2017) Sophie F. Demarche et al.   Journal of Allergy and Clinical Immunology-In Practice

Utility of serum periostin and free IgE levels in evaluating responsiveness to omalizumab in patients with severe asthma

(2016) T. Tajiri et al.   ALLERGY

Roles of Periostin in Respiratory Disorders

(2016) Kenji Izuhara et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Phase 3 Study of Reslizumab in Patients With Poorly Controlled Asthma

(2016) Jonathan Corren et al.   CHEST

Reslizumab for Inadequately Controlled Asthma With Elevated Blood Eosinophil Levels

(2016) Leif Bjermer et al.   CHEST

Use of exercise testing in the evaluation of interventional efficacy: an official ERS statement

(2016) Luis Puente-Maestu et al.   EUROPEAN RESPIRATORY JOURNAL

Efficacy and safety of benralizumab for patients with severe asthma uncontrolled with high-dosage inhaled corticosteroids and long-acting β2-agonists (SIROCCO): a randomised, multicentre, placebo-controlled phase 3 trial

(2016) Eugene R Bleecker et al.   LANCET

Benralizumab, an anti-interleukin-5 receptor α monoclonal antibody, as add-on treatment for patients with severe, uncontrolled, eosinophilic asthma (CALIMA): a randomised, double-blind, placebo-controlled phase 3 trial

(2016) J Mark FitzGerald et al.   LANCET

The prevalence of small airways disease in adult asthma: A systematic literature review

(2016) Omar S. Usmani et al.   RESPIRATORY MEDICINE

Prevalence and reversibility of lung hyperinflation in adult asthmatics with poorly controlled disease or significant dyspnea

(2015) T. Perez et al.   ALLERGY

The minimal important difference for the St George's Respiratory Questionnaire in patients with severe COPD

(2015) Jorrit B.A. Welling et al.   EUROPEAN RESPIRATORY JOURNAL

Blood eosinophil count and prospective annual asthma disease burden: a UK cohort study

(2015) David B Price et al.   Lancet Respiratory Medicine

High blood eosinophil count is associated with more frequent asthma attacks in asthma patients

(2014) Trung N. Tran et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

An official systematic review of the European Respiratory Society/American Thoracic Society: measurement properties of field walking tests in chronic respiratory disease

(2014) Sally J. Singh et al.   EUROPEAN RESPIRATORY JOURNAL

An official European Respiratory Society/American Thoracic Society technical standard: field walking tests in chronic respiratory disease

(2014) Anne E. Holland et al.   EUROPEAN RESPIRATORY JOURNAL

Minimal Clinically Important Difference

(2014) Anna E. McGlothlin et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Mepolizumab Treatment in Patients with Severe Eosinophilic Asthma

(2014) Hector G. Ortega et al.   NEW ENGLAND JOURNAL OF MEDICINE

Benralizumab, an anti-interleukin 5 receptor α monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging study

(2014) Mario Castro et al.   Lancet Respiratory Medicine

Loss of Salmeterol Bronchoprotection against Exercise in Relation to ADRB2 Arg16Gly Polymorphism and Exhaled Nitric Oxide

(2013) Matteo Bonini et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Why inflammatory phenotyping is necessary for successful drug evaluation in asthma and COPD

(2013) Peter G. Gibson   EUROPEAN RESPIRATORY JOURNAL

Sample sizes for clinical trials using sputum eosinophils as a primary outcome

(2013) Angira Dasgupta et al.   EUROPEAN RESPIRATORY JOURNAL

Biomarker surrogates do not accurately predict sputum eosinophil and neutrophil percentages in asthmatic subjects

(2013) Annette T. Hastie et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Monitoring childhood asthma: Web-based diaries and the asthma control test

(2013) Sandra Voorend-van Bergen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Sex differences in asthma symptom profiles and control in the American Lung Association Asthma Clinical Research Centers

(2013) Jennifer W. McCallister et al.   RESPIRATORY MEDICINE

Comparison between an online self-administered and an interviewer-administered version of the Asthma Control Questionnaire: a cross-sectional validation study

(2013) Persijn J Honkoop et al.   Primary Care Respiratory Journal

Beclometasone–formoterol as maintenance and reliever treatment in patients with asthma: a double-blind, randomised controlled trial

(2013) Alberto Papi et al.   Lancet Respiratory Medicine

A trial of beclomethasone/formoterol in COPD using EXACT-PRO to measure exacerbations

(2012) D. Singh et al.   EUROPEAN RESPIRATORY JOURNAL

Asthma outcomes: Symptoms

(2012) Jerry A. Krishnan et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Asthma Symptom Utility Index: Reliability, validity, responsiveness, and the minimal important difference in adult asthmatic patients

(2012) Christian Bime et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Asthma outcomes: Biomarkers

(2012) Stanley J. Szefler et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Theo Vos et al.   LANCET

An Official ATS Clinical Practice Guideline: Interpretation of Exhaled Nitric Oxide Levels (FeNO) for Clinical Applications

(2011) Raed A. Dweik et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Lebrikizumab Treatment in Adults with Asthma

(2011) Jonathan Corren et al.   NEW ENGLAND JOURNAL OF MEDICINE

Perception of airflow obstruction in patients hospitalized for acute asthma

(2010) Steven Q. Davis et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

The increase in exhaled NO following allergen challenge is not associated with airway acidification

(2010) Giovanni Rolla et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Asthma Control Questionnaire in children: validation, measurement properties, interpretation

(2010) E. F. Juniper et al.   EUROPEAN RESPIRATORY JOURNAL

Minimal Clinically Important Difference

(2010) Robert J. Gatchel et al.   SPINE

The role of small airways in monitoring the response to asthma treatment: what is beyond FEV1?

(2009) N. Scichilone et al.   ALLERGY

Relationship between pretreatment specific IgE and the response to omalizumab therapy

(2009) U. Wahn et al.   ALLERGY

The small airways and distal lung compartment in asthma and COPD: a time for reappraisal

(2009) M. Contoli et al.   ALLERGY

An Official American Thoracic Society/European Respiratory Society Statement: Asthma Control and Exacerbations

(2009) Helen K. Reddel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Exhaled Nitric Oxide and Breath Condensate pH in Asthmatic Reactions Induced by Isocyanates

(2009) Silvia Ferrazzoni et al.   CHEST

What defines airflow obstruction in asthma?

(2009) I. Cerveri et al.   EUROPEAN RESPIRATORY JOURNAL

The minimally important difference of the Asthma Control Test

(2009) Michael Schatz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Disability in valued life activities among individuals with systemic lupus erythematosus

(2008) Patricia Katz et al.   ARTHRITIS AND RHEUMATISM

Using the entire cohort in the receiver operating characteristic analysis maximizes precision of the minimal important difference

(2008) Dan Turner et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

The minimal detectable change of the simplified stroke rehabilitation assessment of movement measure

(2008) WS Lu et al.   JOURNAL OF REHABILITATION MEDICINE

Exhaled nitric oxide and asthma control: a longitudinal study in unselected patients

(2007) A. Michils et al.   EUROPEAN RESPIRATORY JOURNAL

Lung function in adults with stable but severe asthma: air trapping and incomplete reversal of obstruction with bronchodilation

(2007) Ronald L. Sorkness et al.   JOURNAL OF APPLIED PHYSIOLOGY

Recommended methods for determining responsiveness and minimally important differences for patient-reported outcomes

(2007) Dennis Revicki et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY