Drug Delivery System in the Treatment of Diabetes Mellitus

Chronic Diabetes Complications: The Need to Move beyond Classical Concepts

(2020) Dídac Mauricio et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Assemblies of Peptide-Cytotoxin Conjugates for Tumor-Homing Chemotherapy

(2019) Jinqiang Wang et al.   ADVANCED FUNCTIONAL MATERIALS

Red blood cell membrane-camouflaged nanoparticles: a novel drug delivery system for antitumor application

(2019) Qing Xia et al.   Acta Pharmaceutica Sinica B

Lecithin nano-liposomal particle as a CRISPR/Cas9 complex delivery system for treating type 2 diabetes

(2019) Eun Yi Cho et al.   JOURNAL OF NANOBIOTECHNOLOGY

Hydrogels and Their Applications in Targeted Drug Delivery

(2019) Radhika Narayanaswamy et al.   MOLECULES

Using DPP-4 inhibitors to modulate beta cell function in type 1 diabetes and in the treatment of diabetic kidney disease

(2019) Hugh Davis et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Fast-Acting Insulin Aspart and the Need for New Mealtime Insulin Analogues in Adults With Type 1 and Type 2 Diabetes: A Canadian Perspective

(2019) Peter Senior et al.   Canadian Journal of Diabetes

Bioinspired and Biomimetic Nanomedicines

(2019) Zhaowei Chen et al.   ACCOUNTS OF CHEMICAL RESEARCH

Enzyme-activatable polymer–drug conjugate augments tumour penetration and treatment efficacy

(2019) Quan Zhou et al.   Nature Nanotechnology

The Role of Protein Tyrosine Phosphatase (PTP)-1B in Cardiovascular Disease and Its Interplay with Insulin Resistance

(2019) Abdelsalam et al.   Biomolecules

WITHDRAWN: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9th edition

(2019) Pouya Saeedi et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

CRISPR-Cas9 system: A new-fangled dawn in gene editing

(2019) Darshana Gupta et al.   LIFE SCIENCES

Glucagon-like peptide 1 (GLP-1)

(2019) T.D. Müller et al.   Molecular Metabolism

Sugar-Lowering Drugs for Type 2 Diabetes Mellitus and Metabolic Syndrome—Strategies for In Vivo Administration: Part-II

(2019) Vieira et al.   Journal of Clinical Medicine

Nanoparticle Delivery Systems in the Treatment of Diabetes Complications

(2019) Eliana B. Souto et al.   MOLECULES

Review of Advanced Hydrogel-Based Cell Encapsulation Systems for Insulin Delivery in Type 1 Diabetes Mellitus

(2019) Albert Espona-Noguera et al.   Pharmaceutics

Cationic polymeric nanoformulation: Recent advances in material design for CRISPR/Cas9 gene therapy

(2019) Kaifeng Chen et al.   Progress in Natural Science-Materials International

Facile synthesis of semi-library of low charge density cationic polyesters from poly(alkylene maleate)s for efficient local gene delivery

(2018) Huijie Yan et al.   BIOMATERIALS

Endogenous Reprogramming of Alpha Cells into Beta Cells, Induced by Viral Gene Therapy, Reverses Autoimmune Diabetes

(2018) Xiangwei Xiao et al.   Cell Stem Cell

Dipeptidyl peptidase-4(DPP-4) inhibitors: promising new agents for autoimmune diabetes

(2018) Xia Wang et al.   CLINICAL AND EXPERIMENTAL MEDICINE

SGLT2 inhibition and kidney protection

(2018) Josselin Nespoux et al.   CLINICAL SCIENCE

Genetics of type 1 diabetes

(2018) Catherine C .Robertson et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Nanotechnology based approaches for anti-diabetic drugs delivery

(2018) Prashant Kesharwani et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

SGLT2 inhibitors: the future for treatment of type 2 diabetes mellitus and other chronic diseases

(2018) Christoph Wanner et al.   DIABETOLOGIA

Hypertension with diabetes mellitus complications

(2018) Daisuke Yamazaki et al.   HYPERTENSION RESEARCH

Microparticles, microcapsules and microspheres: A review of recent developments and prospects for oral delivery of insulin

(2018) Chun Y. Wong et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Phosphatidylserine-Liposomes Promote Tolerogenic Features on Dendritic Cells in Human Type 1 Diabetes by Apoptotic Mimicry

(2018) Silvia Rodriguez-Fernandez et al.   Frontiers in Immunology

Molecular pathways associated with oxidative stress in diabetes mellitus

(2018) Osasenaga Macdonald Ighodaro   BIOMEDICINE & PHARMACOTHERAPY

Glucagon-like peptide-1 receptor agonists in type 2 diabetes treatment: are they all the same?

(2018) Raffaella Gentilella et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Recent advancements in oral administration of insulin-loaded liposomal drug delivery systems for diabetes mellitus

(2018) Chun Y. Wong et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Protective mechanisms of Butyrate on Inflammatory Bowel Disease

(2018) Joao Paulo Bastos Silva et al.   CURRENT PHARMACEUTICAL DESIGN

Protein Corona Liposomes Achieve Efficient Oral Insulin Delivery by Overcoming Mucus and Epithelial Barriers

(2018) Aohua Wang et al.   Advanced Healthcare Materials

Bioinspired butyrate-functionalized nanovehicles for targeted oral delivery of biomacromolecular drugs

(2017) Lei Wu et al.   JOURNAL OF CONTROLLED RELEASE

Potential of insulin nanoparticle formulations for oral delivery and diabetes treatment

(2017) Chun Y. Wong et al.   JOURNAL OF CONTROLLED RELEASE

AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance

(2017) Daniel Garcia et al.   MOLECULAR CELL

Hypoxia and H2O2 Dual-Sensitive Vesicles for Enhanced Glucose-Responsive Insulin Delivery

(2017) Jicheng Yu et al.   NANO LETTERS

Avidity and Bystander Suppressive Capacity of Human Regulatory T Cells Expressing De Novo Autoreactive T-Cell Receptors in Type 1 Diabetes

(2017) Wen-I Yeh et al.   Frontiers in Immunology

AAV-mediated pancreatic overexpression of Igf1 counteracts progression to autoimmune diabetes in mice

(2017) Cristina Mallol et al.   Molecular Metabolism

Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis

(2017) Chunguang Chen et al.   Molecular Metabolism

Type 1 diabetes mellitus

(2017) Anastasia Katsarou et al.   Nature Reviews Disease Primers

Switching from Biphasic Human Insulin to Premix Insulin Analogs: A Review of the Evidence Regarding Quality of Life and Adherence to Medication in Type 2 Diabetes Mellitus

(2016) Nabil El Naggar et al.   ADVANCES IN THERAPY

Molecular mechanisms of ROS production and oxidative stress in diabetes

(2016) P. Newsholme et al.   BIOCHEMICAL JOURNAL

Neutralization Versus Reinforcement of Proinflammatory Cytokines to Arrest Autoimmunity in Type 1 Diabetes

(2016) Ayelet Kaminitz et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Antigen-Encoding Bone Marrow Terminates Islet-Directed Memory CD8+T-Cell Responses to Alleviate Islet Transplant Rejection

(2016) Miranda A. Coleman et al.   DIABETES

Insulinoterapia — nowe kierunki poszukiwań

(2016) Edyta Cichocka et al.   Endokrynologia Polska

Recent advances in the development of protein tyrosine phosphatase 1B inhibitors for Type 2 diabetes

(2016) Shan Qian et al.   Future Medicinal Chemistry

The evolution of diabetic ketoacidosis: An update of its etiology, pathogenesis and management

(2016) Ebenezer A. Nyenwe et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Integration of ATAC-seq and RNA-seq identifies human alpha cell and beta cell signature genes

(2016) Amanda M. Ackermann et al.   Molecular Metabolism

N-Trimethyl Chitosan Chloride-Coated PLGA Nanoparticles Overcoming Multiple Barriers to Oral Insulin Absorption

(2015) Jianyong Sheng et al.   ACS Applied Materials & Interfaces

Glucose-responsive micelles for insulin release

(2015) Xiuhua Li et al.   JOURNAL OF CONTROLLED RELEASE

Immune Interventions to Preserve β Cell Function in Type 1 Diabetes

(2015) Mario R. Ehlers   JOURNAL OF INVESTIGATIVE MEDICINE

Interleukin-10 gene transfer into insulin-producing β cells protects against diabetes in non-obese diabetic mice

(2015) AIJING XU et al.   Molecular Medicine Reports

Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion

(2015) Caroline Bonner et al.   NATURE MEDICINE

Pancreatic islet cell development and regeneration

(2015) Anthony I. Romer et al.   Current Opinion in Endocrinology Diabetes and Obesity

The outer mucus layer hosts a distinct intestinal microbial niche

(2015) Hai Li et al.   Nature Communications

Evolution of Insulin: From Human to Analog

(2014) Joseph M. Tibaldi   AMERICAN JOURNAL OF MEDICINE

Novel drug delivery system: an immense hope for diabetics

(2014) Vineet Kumar Rai et al.   DRUG DELIVERY

Serum Metabolite Signatures of Type 2 Diabetes Mellitus Complications

(2014) Tao Wu et al.   JOURNAL OF PROTEOME RESEARCH

Chronic Exposure to GLP-1 Increases GLP-1 Synthesis and Release in a Pancreatic Alpha Cell Line (α-TC1): Evidence of a Direct Effect of GLP-1 on Pancreatic Alpha Cells

(2014) Salvatore Piro et al.   PLoS One

AMPK activation: a therapeutic target for type 2 diabetes?

(2014) Asish Saha et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Injectable Nano-Network for Glucose-Mediated Insulin Delivery

(2013) Zhen Gu et al.   ACS Nano

Glucose-Responsive Microgels Integrated with Enzyme Nanocapsules for Closed-Loop Insulin Delivery

(2013) Zhen Gu et al.   ACS Nano

α-Cells are dispensable in postnatal morphogenesis and maturation of mouse pancreatic islets

(2013) Chiyo Shiota et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Inducible liver-specific knockdown of protein tyrosine phosphatase 1B improves glucose and lipid homeostasis in adult mice

(2013) C. Owen et al.   DIABETOLOGIA

Modulating GPR40: therapeutic promise and potential in diabetes

(2013) Vincent Poitout et al.   DRUG DISCOVERY TODAY

Novel GPR40 agonist AS2575959 exhibits glucose metabolism improvement and synergistic effect with sitagliptin on insulin and incretin secretion

(2013) Hirotsugu Tanaka et al.   LIFE SCIENCES

11β-Hydroxysteroid Dehydrogenases: Intracellular Gate-Keepers of Tissue Glucocorticoid Action

(2013) Karen Chapman et al.   PHYSIOLOGICAL REVIEWS

Pleiotropic Actions of Insulin Resistance and Inflammation in Metabolic Homeostasis

(2013) J. I. Odegaard et al.   SCIENCE

Discovery of TUG-770: A Highly Potent Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist for Treatment of Type 2 Diabetes

(2013) Elisabeth Christiansen et al.   ACS Medicinal Chemistry Letters

Evaluation of insulin expression and secretion in genetically engineered gut K and L-cells

(2012) Zalinah Ahmad et al.   BMC BIOTECHNOLOGY

Endoplasmic reticulum stress upregulates protein tyrosine phosphatase 1B and impairs glucose uptake in cultured myotubes

(2012) E. Panzhinskiy et al.   DIABETOLOGIA

Restoring insulin production for type 1 diabetes

(2012) Eva Tudurí et al.   Journal of Diabetes

Genetics of the HLA Region in the Prediction of Type 1 Diabetes

(2011) Janelle A. Noble et al.   Current Diabetes Reports

Transcriptional regulation of α-cell differentiation

(2011) N. C. Bramswig et al.   DIABETES OBESITY & METABOLISM

Multifunctional Hybrid Nanogel for Integration of Optical Glucose Sensing and Self-Regulated Insulin Release at Physiological pH

(2010) Weitai Wu et al.   ACS Nano

11β-Hydroxysteroid dehydrogenase type 1 inhibition in type 2 diabetes mellitus

(2010) G. Hollis et al.   DIABETES OBESITY & METABOLISM

Diabetic retinopathy

(2010) Ning Cheung et al.   LANCET

Extreme makeover of pancreatic α-cells

(2010) Kenneth S. Zaret et al.   NATURE

Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

(2010) Fabrizio Thorel et al.   NATURE

Insulin-Like Growth Factor-I Regulation of Immune Function: A Potential Therapeutic Target in Autoimmune Diseases?

(2010) T. J. Smith   PHARMACOLOGICAL REVIEWS

AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome

(2009) Bei B. Zhang et al.   Cell Metabolism

Wheat Germ Agglutinin Functionalized Complexation Hydrogels for Oral Insulin Delivery

(2008) Kristy M. Wood et al.   BIOMACROMOLECULES