Gut T cell–independent IgA responses to commensal bacteria require engagement of the TACI receptor on B cells

IgA Function in Relation to the Intestinal Microbiota

(2018) Andrew J. Macpherson et al.   Annual Review of Immunology

Tumor necrosis factor superfamily member (TNFSF) 13 (APRIL) and TNFSF13B (BAFF) downregulate homeostatic immunoglobulin production in the intestines

(2018) Masaaki Hashiguchi et al.   CELLULAR IMMUNOLOGY

Diet Modifies Colonic Microbiota and CD4 + T Cell Repertoire to Induce Flares of Colitis in Mice With Myeloid-cell Expression of Interleukin 23

(2018) Lili Chen et al.   GASTROENTEROLOGY

Defining the Impact of Host Genotypes on Microbiota Composition Requires Meticulous Control of Experimental Variables

(2018) Andy Wullaert et al.   IMMUNITY

NLRP6 and Dysbiosis: Avoiding the Luring Attraction of Over-Simplification

(2018) Eran Elinav et al.   IMMUNITY

Gut microbiota utilize immunoglobulin A for mucosal colonization

(2018) G. P. Donaldson et al.   SCIENCE

IgA regulates the composition and metabolic function of gut microbiota by promoting symbiosis between bacteria

(2018) Akira Nakajima et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human Secretory IgM Emerges from Plasma Cells Clonally Related to Gut Memory B Cells and Targets Highly Diverse Commensals

(2017) Giuliana Magri et al.   IMMUNITY

A pro-inflammatory role of Fcα/μR on marginal zone B cells in sepsis

(2017) Akira Shibuya et al.   INTERNATIONAL IMMUNOLOGY

Natural polyreactive IgA antibodies coat the intestinal microbiota

(2017) Jeffrey J. Bunker et al.   SCIENCE

An LGG-derived protein promotes IgA production through upregulation of APRIL expression in intestinal epithelial cells

(2016) Y Wang et al.   Mucosal Immunology

IgA production requires B cell interaction with subepithelial dendritic cells in Peyers patches

(2016) A. Reboldi et al.   SCIENCE

High-affinity monoclonal IgA regulates gut microbiota and prevents colitis in mice

(2016) Shinsaku Okai et al.   Nature Microbiology

Differential induction of plasma cells by isoforms of human TACI

(2015) Y. Garcia-Carmona et al.   BLOOD

BALB/c and C57BL/6 Mice Differ in Polyreactive IgA Abundance, which Impacts the Generation of Antigen-Specific IgA and Microbiota Diversity

(2015) Floris Fransen et al.   IMMUNITY

Innate and Adaptive Humoral Responses Coat Distinct Commensal Bacteria with Immunoglobulin A

(2015) Jeffrey J. Bunker et al.   IMMUNITY

Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut microbiota

(2015) Cornelia Lindner et al.   NATURE IMMUNOLOGY

TACI deficiency leads to alternatively activated macrophage phenotype and susceptibility toLeishmaniainfection

(2015) Windy R. Allman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunoglobulin A Coating Identifies Colitogenic Bacteria in Inflammatory Bowel Disease

(2014) Noah W. Palm et al.   CELL

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Eosinophils Promote Generation and Maintenance of Immunoglobulin-A-Expressing Plasma Cells and Contribute to Gut Immune Homeostasis

(2014) Van Trung Chu et al.   IMMUNITY

The role of the adaptive immune system in regulation of gut microbiota

(2014) Lucia M. Kato et al.   IMMUNOLOGICAL REVIEWS

TACI deficiency enhances antibody avidity and clearance of an intestinal pathogen

(2014) Shoichiro Tsuji et al.   JOURNAL OF CLINICAL INVESTIGATION

Interplay of host microbiota, genetic perturbations, and inflammation promotes local development of intestinal neoplasms in mice

(2014) Gerold Bongers et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Generation of colonic IgA-secreting cells in the caecal patch

(2014) Kazunori Masahata et al.   Nature Communications

The TACI Receptor Regulates T-Cell-Independent Marginal Zone B Cell Responses through Innate Activation-Induced Cell Death

(2013) William A. Figgett et al.   IMMUNITY

Local BLyS production by T follicular cells mediates retention of high affinity B cells during affinity maturation

(2013) Radhika Goenka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Microbial colonization influences early B-lineage development in the gut lamina propria

(2013) Duane R. Wesemann et al.   NATURE

Nonredundant Function of Soluble LT 3 Produced by Innate Lymphoid Cells in Intestinal Homeostasis

(2013) A. A. Kruglov et al.   SCIENCE

The Long-Term Stability of the Human Gut Microbiota

(2013) J. J. Faith et al.   SCIENCE

Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine

(2012) Cornelia Lindner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Re-utilization of germinal centers in multiple Peyer's patches results in highly synchronized, oligoclonal and affinity-matured gut IgA responses

(2012) P Bergqvist et al.   Mucosal Immunology

Quality-filtering vastly improves diversity estimates from Illumina amplicon sequencing

(2012) Nicholas A Bokulich et al.   NATURE METHODS

Deficiency in TNFRSF13B (TACI) expands T-follicular helper and germinal center B cells via increased ICOS-ligand expression but impairs plasma cell survival

(2012) X. Ou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Inhibitory Receptor PD-1 Regulates IgA Selection and Bacterial Composition in the Gut

(2012) S. Kawamoto et al.   SCIENCE

TACI deficiency impairs sustained Blimp-1 expression in B cells decreasing long-lived plasma cells in the bone marrow

(2011) S. Tsuji et al.   BLOOD

Prominent Role for Plasmacytoid Dendritic Cells in Mucosal T Cell-Independent IgA Induction

(2011) Hiroyuki Tezuka et al.   IMMUNITY

An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea

(2011) Daniel McDonald et al.   ISME Journal

Mice overexpressing BAFF develop a commensal flora–dependent, IgA-associated nephropathy

(2011) Douglas D. McCarthy et al.   JOURNAL OF CLINICAL INVESTIGATION

Adaptive Immune Regulation in the Gut: T Cell–Dependent and T Cell–Independent IgA Synthesis

(2010) Sidonia Fagarasan et al.   Annual Review of Immunology

Search and clustering orders of magnitude faster than BLAST

(2010) Robert C. Edgar   BIOINFORMATICS

UniFrac: an effective distance metric for microbial community comparison

(2010) Catherine Lozupone et al.   ISME Journal

T Cell-Independent IgA Class Switch Recombination Is Restricted to the GALT and Occurs Prior to Manifest Germinal Center Formation

(2010) P. Bergqvist et al.   JOURNAL OF IMMUNOLOGY

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Indigenous opportunistic bacteria inhabit mammalian gut-associated lymphoid tissues and share a mucosal antibody-mediated symbiosis

(2010) T. Obata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions

(2010) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversible Microbial Colonization of Germ-Free Mice Reveals the Dynamics of IgA Immune Responses

(2010) S. Hapfelmeier et al.   SCIENCE

APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells

(2008) E. Belnoue et al.   BLOOD

Requirement for Lymphoid Tissue-Inducer Cells in Isolated Follicle Formation and T Cell-Independent Immunoglobulin A Generation in the Gut

(2008) Masayuki Tsuji et al.   IMMUNITY

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

(2008) X. Brochet et al.   NUCLEIC ACIDS RESEARCH

IMGT(R), the international ImMunoGeneTics information system(R)

(2008) M.-P. Lefranc et al.   NUCLEIC ACIDS RESEARCH