Identification of potential crucial genes and key pathways in osteosarcoma

Expression profile analysis identifies key genes as prognostic markers for metastasis of osteosarcoma

(2020) Xiaoqing Guan et al.   Cancer Cell International

Overexpression of Notch3 is associated with metastasis and poor prognosis in osteosarcoma patients

(2019) Xuefeng Tang et al.   Cancer Management and Research

Various checkpoint molecules, and tumor-infiltrating lymphocytes in common pediatric solid tumors: Possibilities for novel immunotherapy

(2019) Kazuhiro Mochizuki et al.   PEDIATRIC HEMATOLOGY AND ONCOLOGY

Investigating age‑induced differentially expressed genes and potential molecular mechanisms in osteosarcoma based on integrated bioinformatics analysis

(2019) Jian‑Sheng Wang et al.   Molecular Medicine Reports

Targeting mutant TP53 as a potential therapeutic strategy for the treatment of osteosarcoma

(2019) Fan Tang et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Inhibition of mitochondrial translation selectively targets osteosarcoma

(2019) Jianguo Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Apolipoprotein C1 (APOC1) promotes tumor progression via MAPK signaling pathways in colorectal cancer

(2019) Hui Ren et al.   Cancer Management and Research

Up-regulation of microRNA-496 suppresses proliferation, invasion, migration and in vivo tumorigenicity of human osteosarcoma cells by targeting eIF4E

(2019) Ni-Nan Qi et al.   BIOCHIMIE

MiR-511 mimic transfection inhibits the proliferation, invasion of osteosarcoma cells and reduces metastatic osteosarcoma tumor burden in nude mice via targeting MAPK1

(2019) Junxue Wu et al.   Cancer Biomarkers

Activation of TNF-α/NF-κB axis enhances CRL4BDCAF 11 E3 ligase activity and regulates cell cycle progression in human osteosarcoma cells

(2018) Caiguo Zhang et al.   Molecular Oncology

Identification of potential crucial genes and construction of microRNA-mRNA negative regulatory networks in osteosarcoma

(2018) Yue Pan et al.   HEREDITAS

Two HLA Class II Gene Variants Are Independently Associated with Pediatric Osteosarcoma Risk

(2018) Chenan Zhang et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

VAMP8, a vesicle-SNARE required for RAB37-mediated exocytosis, possesses a tumor metastasis suppressor function

(2018) Yu-Shiuan Wang et al.   CANCER LETTERS

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Predicting novel genes and pathways associated with osteosarcoma by using bioinformatics analysis

(2017) Bo Dong et al.   GENE

Identification of characteristic gene modules of osteosarcoma using bioinformatics analysis indicates the possible molecular pathogenesis

(2017) Hongmin Li et al.   Molecular Medicine Reports

SPARCL1 suppresses osteosarcoma metastasis and recruits macrophages by activation of canonical WNT/β-catenin signaling through stabilization of the WNT–receptor complex

(2017) S-J Zhao et al.   ONCOGENE

Anti-angiogenesis target therapy for advanced osteosarcoma

(2017) Lu Xie et al.   ONCOLOGY REPORTS

Anti-Tumor Necrosis Factor Therapy Inhibits Lung Metastasis in an Osteosarcoma Cell Line

(2017) Hiroaki Kato et al.   ONCOLOGY

The contribution of immune infiltrates and the local microenvironment in the pathogenesis of osteosarcoma

(2017) Marie-Françoise Heymann et al.   CELLULAR IMMUNOLOGY

The Immunology of CD1- and MR1-Restricted T Cells

(2016) Lucia Mori et al.   Annual Review of Immunology

The role of CTLA-4 and PD-1 in anti-tumor immune response and their potential efficacy against osteosarcoma

(2016) Sheng-Dong Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Bioinformatics analysis of differentially expressed pathways related to the metastatic characteristics of osteosarcoma

(2016) Wei Sun et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Targeting microRNAs as key modulators of tumor immune response

(2016) Laura Paladini et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Major Histocompatibility Complex Class II HLA-DRα Is Downregulated by Kaposi's Sarcoma-Associated Herpesvirus-Encoded Lytic Transactivator RTA and MARCH8

(2016) Zhiguo Sun et al.   JOURNAL OF VIROLOGY

Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease

(2016) Jennifer S. Yokoyama et al.   JAMA Neurology

RNAi-mediated silencing of AQP1 expression inhibited the proliferation, invasion and tumorigenesis of osteosarcoma cells

(2015) Zhong Wu et al.   CANCER BIOLOGY & THERAPY

Piperine inhibits proliferation of human osteosarcoma cells via G2/M phase arrest and metastasis by suppressing MMP-2/-9 expression

(2015) Jian Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

EGFR is not a major driver for osteosarcoma cell growth in vitro but contributes to starvation and chemotherapy resistance

(2015) Florian Sevelda et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Identifications of genetic differences between metastatic and non-metastatic osteosarcoma samples based on bioinformatics analysis

(2015) Baoyong Sun et al.   MEDICAL ONCOLOGY

Bioinformatics analysis reveals disturbance mechanism of MAPK signaling pathway and cell cycle in Glioblastoma multiforme

(2014) Wusheng Li et al.   GENE

Induction of apoptosis by diphenyldifluoroketone in osteogenic sarcoma cells is associated with activation of caspases

(2014) SEOK-JIN YANG et al.   ONCOLOGY REPORTS

CluePedia Cytoscape plugin: pathway insights using integrated experimental and in silico data

(2013) Gabriela Bindea et al.   BIOINFORMATICS

Melatonin inhibits the proliferation of human osteosarcoma cell line MG-63

(2013) Lifeng Liu et al.   BONE

Surface proteomic analysis of osteosarcoma identifies EPHA2 as receptor for targeted drug delivery

(2013) J PosthumaDeBoer et al.   BRITISH JOURNAL OF CANCER

Risk Factors for Metastatic Disease at Presentation with Osteosarcoma

(2013) Benjamin J Miller et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Induction of G2/M phase cell cycle arrest and apoptosis by ginsenoside Rf in human osteosarcoma MG-63 cells through the mitochondrial pathway

(2013) WEN-JI SHANGGUAN et al.   ONCOLOGY REPORTS

Identification of osteosarcoma driver genes by integrative analysis of copy number and gene expression data

(2012) Marieke L. Kuijjer et al.   GENES CHROMOSOMES & CANCER

De novo expression of EphA2 in osteosarcoma modulates activation of the mitogenic signalling pathway

(2010) Raphaela Fritsche-Guenther et al.   HISTOPATHOLOGY

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression

(2009) Melissa Paoloni et al.   BMC GENOMICS

Killer Dendritic Cells Link Innate and Adaptive Immunity against Established Osteosarcoma in Rats

(2008) C. Chauvin et al.   CANCER RESEARCH