Enhanced pharmacokinetic performance of dapoxetine hydrochloride via the formulation of instantly-dissolving buccal films with acidic pH modifier and hydrophilic cyclodextrin: Factorial analysis, in vitro and in vivo assessment

Published 2020 View Full Article

Title

Enhanced pharmacokinetic performance of dapoxetine hydrochloride via the formulation of instantly-dissolving buccal films with acidic pH modifier and hydrophilic cyclodextrin: Factorial analysis, in vitro and in vivo assessment

Authors

Keywords

Dapoxetine hydrochloride, Microenvironmental pH, Hydroxypropyl methyl cellulose E5, Maltodextrin, In vivo, mouth dissolving time, Mechanical properties

Journal

Journal of Advanced Research

Volume 24, Issue -, Pages 281-290

Publisher

Elsevier BV

Online

2020-05-01

DOI

10.1016/j.jare.2020.04.019

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