Creating New β-Globin-Expressing Lentiviral Vectors by High-Resolution Mapping of Locus Control Region Enhancer Sequences

Published 2020 View Full Article

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Title
Creating New β-Globin-Expressing Lentiviral Vectors by High-Resolution Mapping of Locus Control Region Enhancer Sequences
Authors
Keywords
hemoglobin, SCD, sickle cell disease, MPRA, Massively Parrallel Reporter Assay, Shuffling, Functional dissection, STARR-seq, ChromHMM, rational lentiviral vector design
Journal
Molecular Therapy-Methods & Clinical Development
Volume 17, Issue -, Pages 999-1013
Publisher
Elsevier BV
Online
2020-04-18
DOI
10.1016/j.omtm.2020.04.006

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