Review
Geriatrics & Gerontology
Steven Jett, Eva Schelbaum, Grace Jang, Camila Boneu Yepez, Jonathan P. Dyke, Silky Pahlajani, Roberta Diaz Brinton, Lisa Mosconi
Summary: Ovarian hormones play a crucial role in women's cognition, and the decline of 17 beta-estradiol during menopause is associated with cognitive aging and Alzheimer's disease risk.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Review
Endocrinology & Metabolism
Manon Dubol, C. Neill Epperson, Julia Sacher, Belinda Pletzer, Birgit Derntl, Rupert Lanzenberger, Inger Sundstrom-Poromaa, Erika Comasco
Summary: Increasing evidence suggests that ovarian hormones influence the brain structure, chemistry, and function of women in their reproductive age, potentially shaping their behavior and mental health. Specifically, these hormones fluctuations appear to have modulatory effects on the reactivity and structure of cortico-limbic brain regions.
FRONTIERS IN NEUROENDOCRINOLOGY
(2021)
Review
Endocrinology & Metabolism
Erin E. Maher, Ashley M. Strzelecki, Jessica J. Weafer, Cassandra D. Gipson
Summary: Clinically, women may have a higher susceptibility to certain aspects of substance use disorders, and this may be influenced by the steroid hormones 17 beta-estradiol (E2) and progesterone (Pg). This review examines the effects of cycling ovarian hormones on nicotine, cocaine, and opioid-related behaviors, and also explores the potential influence of synthetic steroid hormone use. It further investigates the interactions of E2 and Pg in brain reward pathways and their impact on drug-related behaviors, emphasizing the importance of studying women-specific factors in addiction research.
FRONTIERS IN NEUROENDOCRINOLOGY
(2023)
Review
Psychology, Multidisciplinary
Dali Gamsakhurdashvili, Martin I. Antov, Ursula Stockhorst
Summary: This study reviewed original papers on the impact of ovarian-hormone status on facial emotion recognition and emotional memory. Results suggest that features of the stimulus material interact with E2- and P4-related ovarian-hormone status, with oral contraceptive use potentially affecting recognition accuracy of basic and complex emotions.
FRONTIERS IN PSYCHOLOGY
(2021)
Review
Behavioral Sciences
Rachel A. Gilfarb, Benedetta Leuner
Summary: This article summarizes the effects of hormonal fluctuation on the female brain throughout the lifespan, with a focus on the changes in the GABA system. The functional impacts of these changes are discussed, along with potential avenues for further research to improve treatments for women experiencing brain function changes during hormonal transition periods.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2022)
Article
Immunology
Victoria Peer, Khitam Muhsen, Moshe Betser, Manfred S. Green
Summary: Pregnant women have lower immune response to pertussis vaccination compared to non-pregnant women, possibly due to higher levels of hormones during pregnancy. Sex hormones during pregnancy, such as progesterone and estrogen, are negatively associated with anti-pertussis toxin antibody levels.
Review
Cardiac & Cardiovascular Systems
Tingyu Huang, Fiona M. Howse, Nina S. Stachenfeld, Charlotte W. Usselman
Summary: Even in the 21st century, female participants are underrepresented in human physiology research due to the perception that including them is more time consuming, less convenient, and more expensive. However, considering the importance of gonadal hormone fluctuations in governing vascular function and the potential misinterpretation of cardiovascular biomarkers, it is necessary for cardiovascular researchers to include females and accurately track their hormone changes. Saliva-derived measures of gonadal hormones provide a simple and noninvasive method for monitoring, which may facilitate the inclusion of females in cardiovascular research studies.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2023)
Review
Nutrition & Dietetics
Abbie E. Smith-Ryan, Hannah E. Cabre, Joan M. Eckerson, Darren G. Candow
Summary: Despite the lack of research on creatine use among females, supplementation appears to be effective for improving strength and exercise performance in pre-menopausal women, and may also benefit post-menopausal women in terms of skeletal muscle size and function. Additionally, combining creatine with resistance training may have favorable effects on bone health in post-menopausal women.
Article
Engineering, Multidisciplinary
Julija Juric, Hongli Peng, Manshu Song, Frano Vuckovic, Jelena Simunovic, Irena Trbojevi-Akmacic, Youxin Wang, Jiaonan Liu, Qing Gao, Hao Wang, Qiaoyun Chu, Marija Pezer, Wei Wang, Gordan Lauc
Summary: The N-glycosylation of IgG exhibits cyclic periodic changes during the menstrual cycle, which are associated with the menstrual cycle phase and sex hormone concentration. While the average effect of the menstrual cycle on IgG N-glycosylation traits is low, there are significant intrapersonal variations. These findings are important for large sample-size studies on IgG N-glycosylation in women.
Article
Environmental Sciences
Ram B. Jain, Alan Ducatman
Summary: Sex hormones influence excretion of PFAS in rodents, but their influence in humans is unclear. This study analyzed data from NHANES and found that in US females aged ≥20 years, those who took hormonal replacement therapy had higher serum PFAS concentrations compared to nonusers, regardless of hysterectomy or natural menopause status. The results suggest that estrogen hormones may be associated with higher serum PFAS in postmenopausal women.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Endocrinology & Metabolism
Peik M. A. Brundin, Britt-Marie Landgren, Peter Fjallstrom, Mohamed M. M. Shamekh, Jan-Ake Gustafsson, Anders F. F. Johansson, Ivan Nalvarte
Summary: The study reveals the expression patterns of sex hormone receptors in different immune cells and the lack of significant correlation between sex hormone levels and expression of SHR or immune response genes. However, there is a positive correlation between sex hormone-binding globulin and the expression of certain genes. Additionally, immune response genes show significant differences in expression between different phases of the menstrual cycle, suggesting a potential role for sex hormones in immune response.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Review
Immunology
Yepei Huang, Sha Ye, Xiaoyan Bao, Ru Yang, Jian Huang
Summary: Autoimmune progesterone dermatitis is a rare but severe allergic disease in women, with diverse symptoms that require proper understanding for diagnosis and treatment.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Psychology, Clinical
Kristen M. Culbert, Katharine N. Thakkar, Kelly L. Klump
Summary: This narrative review examines the theories behind the heightened risk for psychosis in midlife women and looks at the potential role of ovarian hormones. Studies indicate that the peak ages of midlife psychosis risk in women overlap with the age range of key menopausal stages, especially the perimenopausal transition. However, there is a lack of direct research on menopausal stage. Studies on ovarian hormone effects have mostly focused on earlier developmental stages and events, showing increases in psychotic symptoms during periods of lower estradiol levels. Future research is needed to fill the gaps in our knowledge.
PSYCHOLOGICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Mana Miyamoto, Kenichi Shibuya
Summary: This study aimed to examine potential variations in nutritional intake among female athletes during their menstrual cycle. The findings indicated that there were no notable disparities in nutritional intake across the three phases of the menstrual cycle, suggesting that female athletes may experience comparatively smaller variations in nutrient intake related to their menstrual cycle.
Article
Neurosciences
Handan Noyan, Andac Hamamci, Zeynep Firat, Aysegul Sarsilmaz, Alp Ucok
Summary: This study investigated the effects of menstrual cycle and hormonal fluctuations on resting-state functional connectivity (RS-FC) in schizophrenia patients. The results showed that hormonal differences between groups were associated with changes in clinical symptom severity and RS-FC. Further research is needed to explore these findings.
NEUROPSYCHOBIOLOGY
(2022)
