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Title
A Gq Biased Small Molecule Active at the TSH Receptor
Authors
Keywords
-
Journal
Frontiers in Endocrinology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-06-27
DOI
10.3389/fendo.2020.00372
References
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Related references
Note: Only part of the references are listed.- Thyrotropin Receptor: Allosteric Modulators Illuminate Intramolecular Signaling Mechanisms at the Interface of Ecto- and Transmembrane Domain
- (2019) Patrick Marcinkowski et al. MOLECULAR PHARMACOLOGY
- A New Highly Thyrotropin Receptor-Selective Small-Molecule Antagonist with Potential for the Treatment of Graves' Orbitopathy
- (2018) Patrick Marcinkowski et al. THYROID
- Central Hypothyroidism Due to a TRHR Mutation Causing Impaired Ligand Affinity and Transactivation of Gq
- (2017) Marta García et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Mechanistic insights into GPCR–G protein interactions
- (2016) Jacob P Mahoney et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Rearrangement of the Extracellular Domain/Extracellular Loop 1 Interface Is Critical for Thyrotropin Receptor Activation
- (2016) Joerg Schaarschmidt et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An Enantiomer of an Oral Small-Molecule TSH Receptor Agonist Exhibits Improved Pharmacologic Properties
- (2016) Susanne Neumann et al. Frontiers in Endocrinology
- TSH Receptor Signaling Abrogation by a Novel Small Molecule
- (2016) Rauf Latif et al. Frontiers in Endocrinology
- Thyrotropin Stimulates Differentiation Not Proliferation of Normal Human Thyrocytes in Culture
- (2016) Sarah J. Morgan et al. Frontiers in Endocrinology
- Mechanisms of Action of TSHR Autoantibodies
- (2015) J. Furmaniak et al. HORMONE AND METABOLIC RESEARCH
- New Small Molecule Agonists to the Thyrotropin Receptor
- (2015) Rauf Latif et al. THYROID
- Monte Carlo loop refinement and virtual screening of the thyroid-stimulating hormone receptor transmembrane domain
- (2014) M. Rejwan Ali et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Influence of the Hinge Region and Its Adjacent Domains on Binding and Signaling Patterns of the Thyrotropin and Follitropin Receptor
- (2014) Jörg Schaarschmidt et al. PLoS One
- Novel Insights on Thyroid-Stimulating Hormone Receptor Signal Transduction
- (2013) Gunnar Kleinau et al. ENDOCRINE REVIEWS
- How one TSH receptor antibody induces thyrocyte proliferation while another induces apoptosis
- (2013) Syed A. Morshed et al. JOURNAL OF AUTOIMMUNITY
- TSH induces metallothionein 1 in thyrocytes via Gq/11- and PKC-dependent signaling
- (2013) Christer M Bäck et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- A Drug-Like Antagonist Inhibits Thyrotropin Receptor–Mediated Stimulation of cAMP Production in Graves' Orbital Fibroblasts
- (2012) Susanne Neumann et al. THYROID
- Small molecule TSHR agonists and antagonists
- (2011) S. Neumann et al. ANNALES D ENDOCRINOLOGIE
- Crystal structure of the TSH receptor bound to a blocking type TSHR autoantibody
- (2011) P. Sanders et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Crystal structure of the β2 adrenergic receptor–Gs protein complex
- (2011) Søren G. F. Rasmussen et al. NATURE
- Mutations that silence constitutive signaling activity in the allosteric ligand-binding site of the thyrotropin receptor
- (2010) Ann-Karin Haas et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Signaling-sensitive amino acids surround the allosteric ligand binding site of the thyrotropin receptor
- (2010) Gunnar Kleinau et al. FASEB JOURNAL
- A New Small-Molecule Antagonist Inhibits Graves' Disease Antibody Activation of the TSH Receptor
- (2010) Susanne Neumann et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Species specific thyroid signal transduction: Conserved physiology, divergent mechanisms
- (2010) Y. Song et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Histidine 6.55 Is a Major Determinant of Ligand-Biased Signaling in Dopamine D2L Receptor
- (2010) N. Tschammer et al. MOLECULAR PHARMACOLOGY
- Principles and Determinants of G-Protein Coupling by the Rhodopsin-Like Thyrotropin Receptor
- (2010) Gunnar Kleinau et al. PLoS One
- Small-molecule agonists for the thyrotropin receptor stimulate thyroid function in human thyrocytes and mice
- (2009) S. Neumann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Characterization of Thyrotropin Receptor Antibody-Induced Signaling Cascades
- (2008) Syed A. Morshed et al. ENDOCRINOLOGY
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