Comprehensive Analysis of PD-1 Gene Expression, Immune Characteristics and Prognostic Significance in 1396 Glioma Patients

Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma

(2019) Junfei Zhao et al.   NATURE MEDICINE

Challenges and potential of PD-1/PD-L1 checkpoint blockade immunotherapy for glioblastoma

(2019) Xin Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

PD-1/PD-L1 immune-checkpoint inhibitors in glioblastoma: A concise review

(2019) Mario Caccese et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Pas de Deux: Control of Anti-tumor Immunity by Cancer-Associated Inflammation

(2019) Shabnam Shalapour et al.   IMMUNITY

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

TIGIT and PD-1 dual checkpoint blockade enhances antitumor immunity and survival in GBM

(2018) Alice L. Hung et al.   OncoImmunology

Development of PD-1 and PD-L1 inhibitors as a form of cancer immunotherapy: a comprehensive review of registration trials and future considerations

(2018) Jun Gong et al.   Journal for ImmunoTherapy of Cancer

PD-1 ( PDCD1 ) Promoter Methylation Is a Prognostic Factor in Patients With Diffuse Lower-Grade Gliomas Harboring Isocitrate Dehydrogenase ( IDH ) Mutations

(2018) Lea Kristin Röver et al.   EBioMedicine

PD-1 inhibition has only limited clinical benefit in patients with recurrent high-grade glioma

(2018) Sylvia C. Kurz et al.   NEUROLOGY

Expression of PD-1 by T cells in malignant glioma patients reflects exhaustion and activation

(2018) Tom B Davidson et al.   CLINICAL CANCER RESEARCH

SATB1 Expression Governs Epigenetic Repression of PD-1 in Tumor-Reactive T Cells

(2017) Tom L. Stephen et al.   IMMUNITY

Characterization of PD-1 upregulation on tumor-infiltrating lymphocytes in human and murine gliomas and preclinical therapeutic blockade

(2017) Joost Dejaegher et al.   INTERNATIONAL JOURNAL OF CANCER

Blocking the PD-1/PD-L1 pathway in glioma: a potential new treatment strategy

(2017) Song Xue et al.   Journal of Hematology & Oncology

Correlation of immune phenotype with IDH mutation in diffuse glioma

(2017) Anna Sophie Berghoff et al.   NEURO-ONCOLOGY

Mutational burden, immune checkpoint expression, and mismatch repair in glioma: implications for immune checkpoint immunotherapy

(2017) Tiffany R. Hodges et al.   NEURO-ONCOLOGY

Adjuvant Nivolumab versus Ipilimumab in Resected Stage III or IV Melanoma

(2017) Jeffrey Weber et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immunotherapies for malignant glioma

(2017) Vassiliki A. Boussiotis et al.   ONCOGENE

T cell costimulatory receptor CD28 is a primary target for PD-1–mediated inhibition

(2017) Enfu Hui et al.   SCIENCE

Rescue of exhausted CD8 T cells by PD-1–targeted therapies is CD28-dependent

(2017) Alice O. Kamphorst et al.   SCIENCE

Recurrent glioma clinical trial, CheckMate-143: the game is not over yet

(2017) Anna C. Filley et al.   Oncotarget

Combination Therapy with Anti-PD-1, Anti-TIM-3, and Focal Radiation Results in Regression of Murine Gliomas

(2016) Jennifer E. Kim et al.   CLINICAL CANCER RESEARCH

Glycogen Synthase Kinase 3 Inactivation Drives T-bet-Mediated Downregulation of Co-receptor PD-1 to Enhance CD8+ Cytolytic T Cell Responses

(2016) Alison Taylor et al.   IMMUNITY

Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway

(2016) Vassiliki A. Boussiotis   NEW ENGLAND JOURNAL OF MEDICINE

Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints

(2016) Shohei Koyama et al.   Nature Communications

IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II–III diffuse gliomas

(2015) Adriana Olar et al.   ACTA NEUROPATHOLOGICA

Combination cancer immunotherapy and new immunomodulatory targets

(2015) Kathleen M. Mahoney et al.   NATURE REVIEWS DRUG DISCOVERY

Prospects of immune checkpoint modulators in the treatment of glioblastoma

(2015) Matthias Preusser et al.   Nature Reviews Neurology

Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model

(2015) D. A. Reardon et al.   Cancer Immunology Research

Glioma

(2015) Michael Weller et al.   Nature Reviews Disease Primers

Primary brain tumours in adults

(2012) Damien Ricard et al.   LANCET

Standards of care for treatment of recurrent glioblastoma—are we there yet?

(2012) Michael Weller et al.   NEURO-ONCOLOGY

T Cell Surveillance of Oncogene-Induced Prostate Cancer Is Impeded by T Cell-Derived TGF-β1 Cytokine

(2011) Moses K. Donkor et al.   IMMUNITY

Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection

(2011) Charlly Kao et al.   NATURE IMMUNOLOGY