Article
Chemistry, Multidisciplinary
Emel Kirbas Cilingir, Meghana Sankaran, Jordan M. Garber, Frederic Anthony Vallejo, Mattia Bartoli, Alberto Tagliaferro, Steven Vanni, Regina M. Graham, Roger M. Leblanc
Summary: Carbon dots (CDs) have gained attention for their biocompatibility and tunable photoluminescence, but further analysis is needed before their use in clinical trials. A new type of carbon nitride dot (CND) has been found to selectively uptake cancer cells due to structural similarities with glutamine. The study investigates the effects of surface structural differences on the cellular uptake of CNDs and finds that the uptake mechanism is linked with ASCT2 and LAT1 transporters. CNDs show promise for selective cancer cell targeting by utilizing highly expressed transporters on cancer cells.
Article
Multidisciplinary Sciences
Dhirendra Sahoo, Sushreesangita P. Behera, Jyoti Shakya, Bhaskar Kaviraj
Summary: This study proposes a simple and economical method for synthesizing luminescent MoS2 nanocrystals and evaluates their potential applications in lung cancer cells.
Review
Biotechnology & Applied Microbiology
Shuya Liang
Summary: Bacterial cellulose (BC) is a polysaccharide produced by certain bacteria, possessing unique physical, chemical, and mechanical characteristics. Its biocompatibility, purity, strength, water absorption, and porous structure make it suitable for biomedical applications. However, native BC has limitations, leading to the need for modifications to enhance its properties. This review provides an introduction to BC, production and fabrication methods, and discusses up-to-date modification techniques. The potential applications of BC as a drug delivery system are also highlighted.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Multidisciplinary Sciences
Vu Hoang Minh Doan, Van Tu Nguyen, Sudip Mondal, Thi Mai Thien Vo, Cao Duong Ly, Dinh Dat Vu, Gebremedhin Yonatan Ataklti, Sumin Park, Jaeyeop Choi, Junghwan Oh
Summary: The study utilized IR783-conjugated chitosan-polypyrrole nanocomposites as a theragnostic agent for FL/PA dual-modal imaging, showing good biosafety and efficient photothermal ablation ability. In vitro and in vivo experiments confirmed the potential application of the nanocomposites in photothermal therapy, indicating their promising effectiveness in imaging-guided cancer treatment.
SCIENTIFIC REPORTS
(2021)
Review
Chemistry, Multidisciplinary
Seokhwan Chung, Richard A. Revia, Miqin Zhang
Summary: Graphene quantum dots (GQDs) have excellent properties for various applications in nanomedicine. Recent research focuses on their physicochemical, electronic, magnetic, and biological properties, discussing their use in bioimaging and therapy, as well as technical progress in GQDs synthesis.
ADVANCED MATERIALS
(2021)
Article
Chemistry, Analytical
Yizhong Shen, Tingting Wu, Yuqi Wang, Shao-Lin Zhang, Xueli Zhao, Hong-Yuan Chen, Jing-Juan Xu
Summary: A novel ratiometric fluorescent method was developed to sensitively and specifically report Cathepsin B (CTSB) activity by integrating cancer-targeting recognition moiety and a large emission wavelength shift into a single matrix.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Physical
Ling Yang, Meng Yuan, Ping'an Ma, Xiaorui Chen, Ziyong Cheng, Jun Lin
Summary: Significant progress has been made in drug delivery systems, but stability in the body, off-target effects, and crossing biological barriers are still major challenges. The use of an integrated nanoplatform for efficient targeted delivery and controlled release of drugs is urgently needed. This study reports an integrated strategy of diagnosis and treatment using bacterial peptidoglycan multilayer networks to deliver NIR-II imaged and therapeutic quantum dots (QDs) to circulating neutrophils for targeting tumors. The assembled nanomaterials have good stability and can efficiently target cells for drug delivery and guide drug imaging. Sonodynamic therapy is used to eliminate established solid tumors without recurrence. This study demonstrates the potential of endogenous neutrophils as natural drug carriers and the application of NIR-II fluorescent QDs in biomedical engineering.
Review
Computer Science, Interdisciplinary Applications
Sadia Batool, Hafezeh Nabipour, Seeram Ramakrishna, Masoud Mozafari
Summary: This review discusses the recent advances in nanomaterials for diagnostics and treatments, focusing on the application of nanofibers, nanosensors, and quantum dots. It highlights the potential of nanostructured materials in overcoming the limitations of micro and bulk materials in treatments and diagnostics.
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
(2022)
Review
Chemistry, Multidisciplinary
Aisha Hamidu, William G. Pitt, Ghaleb A. Husseini
Summary: Cancer, one of the leading causes of death worldwide, presents challenges in diagnosis and treatment. Advances in nanomedicine have enabled the detection and investigation of tumor cells at a cellular level using quantum dots, showcasing their potential for various applications.
Article
Chemistry, Multidisciplinary
Xiaobo Zhou, Lingfeng Zhao, Ke Zhang, Chaojie Yang, Shijie Li, Xiaoxia Kang, Guo Li, Qi Wang, Haiwei Ji, Mingmin Wu, Jinxia Liu, Yuling Qin, Li Wu
Summary: This study presented a strategy for designing and fabricating narrow emissive AIEdots with tunable wavelengths by constructing a light-harvesting system with high energy transfer efficiency, resulting in high brightness and narrow emission.
Article
Chemistry, Multidisciplinary
Li Xu, Wei Fu, Lei Bao, Guanglin Wang, Wanping Wang, Wei Wang, Kun Xiang, Nengmei Deng, Xucheng Fu, Juncheng Jin
Summary: Homogeneous photoluminescent MoS2 QDs were successfully produced using structurally stable MOF MIL-101 as limited nanoreactors, opening up a new route for fabricating other photoluminescent QDs and their derived nanomaterials.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Mehdi Yoosefian, Mitra Fouladi, Leonard Ionut Atanase
Summary: This study investigated the efficiency and loading of a carbon-based nanocarrier for anticancer drug delivery. The selected material demonstrated good stability, and the presence of a surface modifier delayed the adsorption of the drug initially.
Article
Materials Science, Multidisciplinary
Zhipeng Dong, Nanxia Zhang, Jiahao Zhang, Jun Luo, Yisong Xu, Weifang Tang, Baofen Ye, Yue Wang
Summary: Metal-containing nanomaterials have diverse compositions and structures, making them attractive for various applications. In this study, we modified dendritic polyethylene glycol on a folate-nickel nanotube to create a new type of metal-containing nanotube, PEG-FA-Ni NTs. These nanotubes exhibited excellent antitumor activity comparable to commonly used drugs, and may achieve optimal antitumor effects by damaging DNA, blocking cell cycle, and inducing apoptosis. The results suggest that PEG-FA-Ni NTs could be a promising nanomedicine for cancer therapy.
JOURNAL OF MATERIALS SCIENCE
(2022)
Article
Chemistry, Applied
Debiprasad Roy, Alpana Mukhuty, Chandrani Fouzder, Nandagopal Bar, Shreyashi Chowdhury, Rakesh Kundu, Pranesh Chowdhury
Summary: Multi-emissive silicon quantum dots (SQDs) are a promising advanced material in biomedical research, with unique optical properties and ideal size for cellular imaging. SQDs can be used for cell imaging, drug tagging, enhancing drug efficacy, and exploring the biochemistry of drug delivery systems.
Article
Chemistry, Multidisciplinary
Amit Fischer, Pu Zhang, Yu Ouyang, Yang Sung Sohn, Ola Karmi, Rachel Nechushtai, Eli Pikarsky, Itamar Willner
Summary: In this study, the assembly of ATP and miRNA-responsive DNA tetrahedra-functionalized carboxymethyl cellulose hydrogel microcapsules is presented. The microcapsules are selectively unlocked and release the loaded drugs in the presence of ATP or miRNA-141. The functionalized microcapsules with DNA tetrahedra nanostructures exhibit superior permeation into cells, particularly breast cancer cells. The stimuli-responsive, drug-loaded, DNA tetrahedra-modified microcapsules show superior and selective cytotoxicity toward cancer cells.
Review
Physics, Multidisciplinary
Xiao-Hui Li, Yi-Xuan Guo, Yujie Ren, Jia-Jun Peng, Ji-Shu Liu, Cong Wang, Han Zhang
Summary: In this paper, the progress of narrow-bandgap materials in terms of nonlinear optical properties, band structure, preparation methods, and applications is reviewed. These materials exhibit strong nonlinear absorption characteristics when interacting with short pulse lasers, leading to optical limiting or saturable absorption. Some of these materials have been utilized for generating ultrashort pulses.
FRONTIERS OF PHYSICS
(2022)
Article
Multidisciplinary Sciences
Zhinan Guo, Rui Cao, Huide Wang, Xi Zhang, Fanxu Meng, Xue Chen, Siyan Gao, David K. Sang, Thi Huong Nguyen, Anh Tuan Duong, Jinlai Zhao, Yu-Jia Zeng, Sunglae Cho, Bing Zhao, Ping-Heng Tan, Han Zhang, Dianyuan Fan
Summary: In this work, stable p-type 2D-layered beta-InSe was prepared via temperature gradient method, and its strong anisotropic transport and high photoresponse properties were experimentally and theoretically proven. Consequently, beta-InSe is identified as a competitive candidate for filter-free polarization-sensitive photodetectors.
NATIONAL SCIENCE REVIEW
(2022)
Review
Materials Science, Multidisciplinary
Bibi Mary Francis, Joice Sophia Ponraj, Balaji Dhanabalan, Rajesh Kumar Manavalan, Pandiyarasan Veluswamy, Peng Yin, Omar A. Al-Hartomy, Ahmed Al-Ghamdi, Swelm Wageh, Han Zhang, Sathish Chander Dhanabalan
Summary: This review provides an overview of the application of functional inks based on two-dimensional (2D) materials in printed photonics. It combines the unique optical properties of 2D materials with different printing techniques to fabricate revolutionary photonic devices. The review discusses the optical properties of commonly used 2D materials, the properties of functional inks, and compatible substrates for printed photonics. It also explains the commonly used methods for fabricating photonic devices using 2D material-based inks, with a focus on inkjet printing. Several examples of printed photonic devices using 2D material-based functional inks are presented. Finally, the potential of 2D materials to improve the performance and functionality of photonic devices is discussed.
Article
Nanoscience & Nanotechnology
Jianlong Kang, Feicui Xu, Chen Zhang, Feng Li, Omar A. Al-Hartomy, Ahmed Al-Ghamdi, Swelm. Wageh, Guanghui Zhao, Tingqiang Yang, Han Zhang
Summary: In this study, ammonia sensing properties of VS2 nanosheets (NSs) based chemiresistive gas sensor were investigated. It was found that VS2 NSs have high affinity and selectivity towards ammonia, allowing for detection at low working temperatures. The mechanism for ammonia sensing involves electron transfer from absorbed ammonia molecules to VS2 NSs, leading to resistance enhancement.
ADVANCED ELECTRONIC MATERIALS
(2022)
Article
Nanoscience & Nanotechnology
Qingbo Wang, Jianlong Kang, Pan Wang, Jiangyong He, Yicong Liu, Zhi Wang, Han Zhang, Yan-ge Liu
Summary: Passively mode-locked lasers are effective in generating ultrashort pulses. In recent years, exploring 2D material-based saturable absorbers has become a hot topic in ultrafast photonics. Germanene, a novel 2D Dirac material with ultrafast optical response and broadband optical absorption, is considered a promising alternative for saturable absorbers in mode-locked fiber lasers. In this paper, germanium nanosheets were prepared and their saturable absorption properties were systematically characterized. Ultrashort pulse generation using germanene saturable absorbers in fiber lasers was successfully achieved, covering a broad range of wavelengths.
Article
Chemistry, Multidisciplinary
Fei Zheng, Zhi Chen, Jingfeng Li, Rui Wu, Bin Zhang, Guohui Nie, Zhongjian Xie, Han Zhang
Summary: The novel CRISPR-empowered SPR sensing platform developed in this study combines CRISPR technology with SPR sensor technology to enable rapid, precise, sensitive, and specific detection of target gene sequences.
Article
Nanoscience & Nanotechnology
Shanshan Dang, Yanmei Mo, Junqing Zeng, Yunjie Xu, Zhongjian Xie, Han Zhang, Bin Zhang, Guohui Nie
Summary: In this study, a multifunctional nanoplatform was developed by immobilizing monodispersed ultrasmall Pd nanoclusters and a photosensitizer Thp on the surface of Ti3C2Tx MXene nanosheets, resulting in the Pd-Thp-Ti3C2Tx nanocomposite. Through the synergistic effect of photothermal therapy and photodynamic therapy, the nanocomposite induced apoptosis in tumor cells, demonstrating good biocompatibility and potential biomedical applications.
Article
Nanoscience & Nanotechnology
Linghua Jin, Huide Wang, Rui Cao, Karim Khan, Ayesha Khan Tareen, Swelm Wageh, Ahmed A. Al-Ghamdi, Shaojuan Li, Dabing Li, Ye Zhang, Han Zhang
Summary: Researchers have explored the use of ferroelectric materials to improve the performance of two-dimensional photonic and optoelectronic devices. Ferroelectrics can adjust the carrier concentration, mobility, and bandgap of two-dimensional materials, allowing for control over their photonic and optoelectronic properties. The polarization of ferroelectrics can be modulated by incident light, and the wavelengths of light can be tuned by switching the polarization, thereby enhancing the performance of two-dimensional photonic and optoelectronic devices. Two-dimensional materials have great potential in photonics and optoelectronics due to their tunable bandgap.
Review
Chemistry, Multidisciplinary
Yunhai Xiong, Duo Xu, Yiping Feng, Guangjie Zhang, Pei Lin, Xiang Chen
Summary: 2D semiconductors, with their superior carrier mobility and gate-control capability at atomic thickness, are considered as one of the best options to extend Moore's law. However, reliable p-type 2D semiconductors with majority carriers of holes are still scarce. This article reviews the material toolkit, synthesis strategies, device basics, and digital electronics related to p-type 2D semiconductors, and discusses their opportunities, challenges, and prospects for future electronic applications.
ADVANCED MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Tianzhong Li, Jinyong Wang, Tongkai Chen, Swelm Wageh, Ahmed A. Al-Ghamdi, Jiangtian Yu, Zhongjian Xie, Han Zhang
Summary: In this study, a drug formulation based on lactic acid bacteria (LAB) was developed to produce reactive oxygen species (ROS) in tumors and induce host immunity. The LAB were modified with zeolitic imidazolate framework-67 (ZIF-67) and effectively delivered into tumor cells, leading to the generation of ROS upon light exposure. The bacterial hybrid induced tumor shrinkage through photodynamic therapy and stimulated inflammation to attract immune cells for cancer elimination.
SCIENCE CHINA-MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Dapeng Huang, Fei Liang, Ruiqi Guo, Dazhi Lu, Jiyang Wang, Haohai Yu, Huaijin Zhang
Summary: In this study, the broadband self-trapped exciton (STE) states are demonstrated for the first time in Mo-vacancy-rich MoSi2N4 films. The modulation effect of STE states on nonlinear optical processes is verified, which opens up new possibilities for the construction of novel devices and practical applications.
ADVANCED OPTICAL MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Xiufeng Song, Yuxuan Jian, Xusheng Wang, Jiawei Chen, Qingsong Shan, Shengli Zhang, Zhanyang Chen, Xiang Chen, Haibo Zeng
Summary: Perovskites have great potential for use in photodetectors due to their exceptional electrical and optical properties. By integrating two-dimensional materials with perovskites, it is possible to achieve excellent optoelectrical properties by utilizing the high carrier mobility of the 2D materials and strong light absorption of perovskite. In this study, a photodetector based on the WTe2/CsPbI3 heterostructure is demonstrated. The WTe2/CsPbI3 heterojunction facilitates efficient charge transfer, leading to quenching and shortened lifetime of photoluminescence for CsPbI3 perovskite. Coupling with WTe2 significantly improves the photoresponsivity of the CsPbI3 photodetector due to the high-gain photogating effect. The WTe2/CsPbI3 heterojunction photodetector exhibits a large responsivity of 1157 A W-1 and a high detectivity of 2.1 x 10(13) Jones, paving the way for high-performance optoelectronic devices based on 2D materials/perovskite heterojunctions.
Article
Materials Science, Multidisciplinary
Duo Xu, Junji Li, Yunhai Xiong, Han Li, Jialin Yang, Wenqiang Liu, Lianfu Jiang, Kairui Qu, Tong Zhao, Xinyu Shi, Shengli Zhang, Dan Shan, Xiang Chen, Haibo Zeng
Summary: In order to prevent continuous outbreaks of SARS-CoV-2, it is urgent to develop more efficient identification approaches of variants. In this study, two-dimensional indium selenide field-effect transistors were used to identify SARS-CoV-2 variants and achieved sub-fM detection limits and the ability to recognize single-nucleotide variations within 15 minutes.
