Sex-Specific Regulation of Gene Expression Networks by Surfactant Protein A (SP-A) Variants in Alveolar Macrophages in Response to Klebsiella pneumoniae

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FKBP5 rs4713916: A Potential Genetic Predictor of Interindividual Different Response to Inhaled Corticosteroids in Patients with Chronic Obstructive Pulmonary Disease in a Real-Life Setting

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Major Effect of Oxidative Stress on the Male, but Not Female, SP-A1 Type II Cell miRNome

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Differential Impact of Co-expressed SP-A1/SP-A2 Protein on AM miRNome; Sex Differences

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Structural and Functional Determinants of Rodent and Human Surfactant Protein A: A Synthesis of Binding and Computational Data

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SAMHD1: Recurring roles in cell cycle, viral restriction, cancer, and innate immunity

(2018) Christopher H. Mauney et al.   AUTOIMMUNITY

Pulmonary Surfactant Promotes Virulence Gene Expression and Biofilm Formation in Klebsiella pneumoniae

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Survival of Surfactant Protein-A1 and SP-A2 Transgenic Mice After Klebsiella pneumoniae Infection, Exhibits Sex-, Gene-, and Variant Specific Differences; Treatment With Surfactant Protein Improves Survival

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SP-A2 contributes to miRNA-mediated sex differences in response to oxidative stress: pro-inflammatory, anti-apoptotic, and anti-oxidant pathways are involved

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Determining prognosis in acute exacerbation of COPD

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Human Pulmonary Surfactant Protein SP-A1 Provides Maximal Efficiency of Lung Interfacial Films

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Klebsiella pneumoniae: Going on the Offense with a Strong Defense

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Single-cell analysis reveals differential regulation of the alveolar macrophage actin cytoskeleton by surfactant proteins A1 and A2: implications of sex and aging

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14-3-3 isoforms bind directly exon B of the 5′-UTR of human surfactant protein A2 mRNA

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Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system

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An 11-nt sequence polymorphism at the 3′UTR of human SFTPA1 and SFTPA2 gene variants differentially affect gene expression levels and miRNA regulation in cell culture

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DNA methylation profile and expression of surfactant protein A2 gene in lung cancer

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Frequency of Klebsiella pneumoniae Carbapenemase (KPC)–Producing and Non-KPC-Producing Klebsiella Species Contamination of Healthcare Workers and the Environment

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Sex differences in the acute in vivo effects of different human SP-A variants on the mouse alveolar macrophage proteome

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Klebsiella pneumoniae Oropharyngeal Carriage in Rural and Urban Vietnam and the Effect of Alcohol Consumption

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Effect of ozone exposure and infection on bronchoalveolar lavage: Sex differences in response patterns

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Surfactant Protein A Suppresses Lung Cancer Progression by Regulating the Polarization of Tumor-Associated Macrophages

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Pulmonary surfactant protein A and surfactant lipids upregulate IRAK-M, a negative regulator of TLR-mediated inflammation in human macrophages

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When bacteria target the nucleus: the emerging family of nucleomodulins

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Genetic Complexity of the Human Innate Host Defense Molecules, Surfactant Protein A1 (SP-A1) and SP-A2—Impact on Function

(2012) Joanna Floros et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Gonadal hormones and oxidative stress interaction differentially affects survival of male and female mice after lungKlebsiella Pneumoniaeinfection

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Impact of sex and ozone exposure on the course of pneumonia in wild type and SP-A (−/−) mice

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Sex differences in the response of the alveolar macrophage proteome to treatment with exogenous surfactant protein-A

(2012) David S Phelps et al.   Proteome Science

The untranslated exon B of human surfactant protein A2 mRNAs is an enhancer for transcription and translation

(2011) Patricia Silveyra et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Surfactant protein A is defective in abrogating inflammation in asthma

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Earliest Innate Immune Responses Require Macrophage RelA during Pneumococcal Pneumonia

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Pattern Recognition Receptors and Inflammation

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HumanizedSFTPA1andSFTPA2Transgenic Mice Reveal Functional Divergence of SP-A1 and SP-A2

(2010) Guirong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lung environment determines unique phenotype of alveolar macrophages

(2009) Amanda M. Guth et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

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Gene expression profiling of human alveolar macrophages infected by B. anthracisspores demonstrates TNF-α and NF-κb are key components of the innate immune response to the pathogen

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Scavenger receptors: role in innate immunity and microbial pathogenesis

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Surfactant Protein A Modulates Cell Surface Expression of CR3 on Alveolar Macrophages and Enhances CR3-mediated Phagocytosis

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The IKK Complex, a Central Regulator of NF- B Activation

(2009) A. Israel   Cold Spring Harbor Perspectives in Biology

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Inhibition of pulmonary antibacterial defense by interferon-γ during recovery from influenza infection

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(2008) Joseph P. Mizgerd   NEW ENGLAND JOURNAL OF MEDICINE

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Impact of ozone exposure on the phagocytic activity of human surfactant protein A (SP-A) and SP-A variants

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A genome-wide analysis of LPS tolerance in macrophages

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