Comparison of regional flortaucipir PET with quantitative tau immunohistochemistry in three subjects with Alzheimer’s disease pathology: a clinicopathological study

First in-human PET study of 3 novel tau radiopharmaceuticals: [11C]RO6924963, [11C]RO6931643, and [18F]RO6958948

(2018) Dean F. Wong et al.   JOURNAL OF NUCLEAR MEDICINE

In vivo [18F]-AV-1451 tau-PET imaging in sporadic Creutzfeldt-Jakob disease

(2018) Gregory S. Day et al.   NEUROLOGY

Early Clinical PET Imaging Results with the Novel PHF-Tau Radioligand [F18]-T808

(2018) David T. Chien et al.   JOURNAL OF ALZHEIMERS DISEASE

Correlation of In Vivo [18F]Flortaucipir With Postmortem Alzheimer Disease Tau Pathology

(2018) Ruben Smith et al.   JAMA Neurology

Preclinical Evaluation of 18 F-JNJ64349311, a Novel PET Tracer for Tau Imaging

(2017) Lieven Declercq et al.   JOURNAL OF NUCLEAR MEDICINE

MAO-B Inhibitors Do Not Block In Vivo Flortaucipir([18F]-AV-1451) Binding

(2017) Allan K. Hansen et al.   MOLECULAR IMAGING AND BIOLOGY

Tau PET imaging: present and future directions

(2017) Laure Saint-Aubert et al.   Molecular Neurodegeneration

The tau positron-emission tomography tracer AV-1451 binds with similar affinities to tau fibrils and monoamine oxidases

(2017) Céline Vermeiren et al.   MOVEMENT DISORDERS

Aβ-amyloid and Tau Imaging in Dementia

(2017) Victor L. Villemagne et al.   SEMINARS IN NUCLEAR MEDICINE

Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain

(2017) Kok Pin Ng et al.   Alzheimers Research & Therapy

Lessons learned about [F-18]-AV-1451 off-target binding from an autopsy-confirmed Parkinson’s case

(2017) Marta Marquié et al.   Acta Neuropathologica Communications

Tau neuropathology correlates with FDG-PET, but not AV-1451-PET, in progressive supranuclear palsy

(2016) Ruben Smith et al.   ACTA NEUROPATHOLOGICA

[18F]AV-1451 tau-PET uptake does correlate with quantitatively measured 4R-tau burden in autopsy-confirmed corticobasal degeneration

(2016) Keith A. Josephs et al.   ACTA NEUROPATHOLOGICA

Multimodal evaluation demonstrates in vivo 18F-AV-1451 uptake in autopsy-confirmed corticobasal degeneration

(2016) Corey T. McMillan et al.   ACTA NEUROPATHOLOGICA

In vivo cortical spreading pattern of tau and amyloid in the Alzheimer disease spectrum

(2016) Hanna Cho et al.   ANNALS OF NEUROLOGY

18F-AV-1451 tau PET imaging correlates strongly with tau neuropathology inMAPTmutation carriers

(2016) Ruben Smith et al.   BRAIN

Regional profiles of the candidate tau PET ligand18F-AV-1451 recapitulate key features of Braak histopathological stages

(2016) Adam J. Schwarz et al.   BRAIN

Kinetics of the Tau PET Tracer 18F-AV-1451 (T807) in Subjects with Normal Cognitive Function, Mild Cognitive Impairment, and Alzheimer Disease

(2016) S. Shcherbinin et al.   JOURNAL OF NUCLEAR MEDICINE

PET Imaging of Tau Deposition in the Aging Human Brain

(2016) Michael Schöll et al.   NEURON

Dynamic PET Measures of Tau Accumulation in Cognitively Normal Older Adults and Alzheimer’s Disease Patients Measured Using [18F] THK-5351

(2016) Samuel N. Lockhart et al.   PLoS One

Tau and Aβ imaging, CSF measures, and cognition in Alzheimer’s disease

(2016) Matthew R. Brier et al.   Science Translational Medicine

[18F]AV-1451 PET in behavioral variant frontotemporal dementia due to MAPT mutation

(2016) W. Richard Bevan Jones et al.   Annals of Clinical and Translational Neurology

An autoradiographic evaluation of AV-1451 Tau PET in dementia

(2016) Val J. Lowe et al.   Acta Neuropathologica Communications

Florbetaben PET imaging to detect amyloid beta plaques in Alzheimer's disease: Phase 3 study

(2015) Osama Sabri et al.   Alzheimers & Dementia

Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue

(2015) Marta Marquié et al.   ANNALS OF NEUROLOGY

Tau positron emission tomographic imaging in aging and early Alzheimer disease

(2015) Keith A. Johnson et al.   ANNALS OF NEUROLOGY

Cerebral Cortical Aβ42and PHF-τ in 325 Consecutive Brain Autopsies Stratified by Diagnosis, Location, andAPOE

(2015) Nadia Postupna et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

18F-THK5351: A Novel PET Radiotracer for Imaging Neurofibrillary Pathology in Alzheimer Disease

(2015) R. Harada et al.   JOURNAL OF NUCLEAR MEDICINE

Phase 3 Trial of Flutemetamol Labeled With Radioactive Fluorine 18 Imaging and Neuritic Plaque Density

(2015) Craig Curtis et al.   JAMA Neurology

[18F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease

(2013) Chun-Fang Xia et al.   Alzheimers & Dementia

Novel 18F-Labeled Arylquinoline Derivatives for Noninvasive Imaging of Tau Pathology in Alzheimer Disease

(2013) N. Okamura et al.   JOURNAL OF NUCLEAR MEDICINE

A 2-process model for neuropathology of Alzheimer's disease

(2013) Dan Mungas et al.   NEUROBIOLOGY OF AGING

Imaging of Tau Pathology in a Tauopathy Mouse Model and in Alzheimer Patients Compared to Normal Controls

(2013) Masahiro Maruyama et al.   NEURON

National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

(2012) Bradley T. Hyman et al.   Alzheimers & Dementia

Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

(2012) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study

(2012) Christopher M Clark et al.   LANCET NEUROLOGY

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

(2011) Thomas J. Montine et al.   ACTA NEUROPATHOLOGICA

Novel Antibody Capture Assay for Paraffin-Embedded Tissue Detects Wide-Ranging Amyloid Beta and Paired Helical Filament-Tau Accumulation in Cognitively Normal Older Adults

(2011) Nadia Postupna et al.   BRAIN PATHOLOGY

Neuropathology and Cognitive Impairment in Alzheimer Disease: A Complex but Coherent Relationship

(2008) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY