Nebulized Therapies in COPD: Past, Present, and the Future

Peak Inspiratory Flow Rate: An Emerging Biomarker in COPD

(2019) Donald A Mahler   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cardiovascular safety of revefenacin, a once-daily, lung-selective, long-acting muscarinic antagonist for nebulized therapy of chronic obstructive pulmonary disease: Evaluation in phase 3 clinical trials

(2019) James F. Donohue et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Economic impact and chronic obstructive pulmonary disease outcomes of a comprehensive inhaler to nebulization therapy protocol implementation in a large multi-state healthcare system

(2019) Trent Larson   CURRENT MEDICAL RESEARCH AND OPINION

Revefenacin, a once-daily, lung-selective, long-acting muscarinic antagonist for nebulized therapy: Safety and tolerability results of a 52-week phase 3 trial in moderate to very severe chronic obstructive pulmonary disease

(2019) James F. Donohue et al.   RESPIRATORY MEDICINE

The Respimat® Soft Mist Inhaler: Implications of Drug Delivery Characteristics for Patients

(2019) Takashi Iwanaga et al.   CLINICAL DRUG INVESTIGATION

Ensifentrine (RPL554): an investigational PDE3/4 inhibitor for the treatment of COPD

(2019) Mario Cazzola et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Inhaled Therapy in Respiratory Disease: The Complex Interplay of Pulmonary Kinetic Processes

(2018) Jens Markus Borghardt et al.   Canadian Respiratory Journal

Once-Daily Single-Inhaler Triple versus Dual Therapy in Patients with COPD

(2018) David A. Lipson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Aerosol Delivery Devices for Obstructive Lung Diseases

(2018) Roy A Pleasants et al.   Respiratory Care

Results of a Patient Survey Regarding COPD Knowledge, Treatment Experiences, and Practices With Inhalation Devices

(2018) Rajiv Dhand et al.   Respiratory Care

Nebulized Corticosteroids in the Treatment of COPD Exacerbations: Systematic Review, Meta-Analysis, and Clinical Perspective

(2018) Roy A Pleasants et al.   Respiratory Care

An inhaled “bifunctional” dual PDE3/4 inhibitor provides additional short-term improvements in lung function compared to existing classes of bronchodilator: implications for future treatment of COPD

(2018) Mario Cazzola et al.   EUROPEAN RESPIRATORY JOURNAL

Long-term macrolide treatment for the prevention of acute exacerbations in COPD: a systematic review and meta-analysis

(2018) Yanan Cui et al.   International Journal of Chronic Obstructive Pulmonary Disease

Chronic Respiratory Infection in Patients with Chronic Obstructive Pulmonary Disease: What Is the Role of Antibiotics?

(2017) Marc Miravitlles et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Peak Inspiratory Flow Rate in Chronic Obstructive Pulmonary Disease: Implications for Dry Powder Inhalers

(2017) Sohini Ghosh et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Long-term safety of glycopyrrolate/eFlow ® CS in moderate-to-very-severe COPD: Results from the Glycopyrrolate for Obstructive Lung Disease via Electronic Nebulizer (GOLDEN) 5 randomized study

(2017) Gary T. Ferguson et al.   RESPIRATORY MEDICINE

Efficacy and safety of glycopyrrolate/eFlow ® CS (nebulized glycopyrrolate) in moderate-to-very-severe COPD: Results from the glycopyrrolate for obstructive lung disease via electronic nebulizer (GOLDEN) 3 and 4 randomized controlled trials

(2017) Edward Kerwin et al.   RESPIRATORY MEDICINE

Effectiveness of treatment with nebulized colistin in patients with COPD

(2017) Nuria Bruguera-Avila et al.   International Journal of Chronic Obstructive Pulmonary Disease

Evaluation effects of nebulized gentamicin in exacerbation of chronic obstructive lung disease

(2016) Shahin Asgari-Savadjani et al.   Journal of Research in Medical Sciences

A review of nebulized drug delivery in COPD

(2016) Donald Tashkin   International Journal of Chronic Obstructive Pulmonary Disease

One-Year Safety and Efficacy Study of Arformoterol Tartrate in Patients With Moderate to Severe COPD

(2014) James F. Donohue et al.   CHEST

In vitro, in vivo and ex vivo models for studying particle deposition and drug absorption of inhaled pharmaceuticals

(2013) Kamrun Nahar et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Comparison of Dry Powder versus Nebulized Beta-Agonist in Patients with COPD Who Have Suboptimal Peak Inspiratory Flow Rate

(2013) Donald A. Mahler et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

“Nebs No More After 24”: A Pilot Program to Improve the Use of Appropriate Respiratory Therapies

(2013) Christopher Moriates et al.   JAMA Internal Medicine

Considerations for managing chronic obstructive pulmonary disease in the elderly

(2013) George Taffet et al.   Clinical Interventions in Aging

Dysfunctional lung anatomy and small airways degeneration in COPD

(2013) Pierre-Régis Burgel et al.   International Journal of Chronic Obstructive Pulmonary Disease

Efficacy and safety of RPL554, a dual PDE3 and PDE4 inhibitor, in healthy volunteers and in patients with asthma or chronic obstructive pulmonary disease: findings from four clinical trials

(2013) Lui G Franciosi et al.   Lancet Respiratory Medicine

Prevalence and COPD Phenotype for a Suboptimal Peak Inspiratory Flow Rate against the Simulated Resistance of the Diskus® Dry Powder Inhaler

(2012) Donald A. Mahler et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Chronic bronchial infection in COPD. Is there an infective phenotype?

(2012) Zinka Matkovic et al.   RESPIRATORY MEDICINE

Practical aspects of inhaler use in the management of chronic obstructive pulmonary disease in the primary care setting

(2012) Barbara Yawn et al.   International Journal of Chronic Obstructive Pulmonary Disease

Inhaler device selection: Special considerations in elderly patients with chronic obstructive pulmonary disease

(2011) R. Barrons et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

What the pulmonary specialist should know about the new inhalation therapies

(2011) B. L. Laube et al.   EUROPEAN RESPIRATORY JOURNAL

Azithromycin for Prevention of Exacerbations of COPD

(2011) Richard K. Albert et al.   NEW ENGLAND JOURNAL OF MEDICINE

Omron NE U22: Comparison Between Vibrating Mesh and Jet Nebulizer

(2010) Shibu Skaria et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Tobramycin Nebulizer Solution in severe COPD patients colonized with Pseudomonas aeruginosa: effects on bronchial Inflammation

(2008) Roberto Dal Negro et al.   ADVANCES IN THERAPY

Inspiratory flow rates at different levels of resistance in elderly COPD patients

(2007) W. Janssens et al.   EUROPEAN RESPIRATORY JOURNAL

Efficacy and safety of formoterol fumarate delivered by nebulization to COPD patients

(2007) Nicholas J. Gross et al.   RESPIRATORY MEDICINE