Maslinic Acid Enhances Docetaxel Response in Human Docetaxel-Resistant Triple Negative Breast Carcinoma MDA-MB-231 Cells via Regulating MELK-FoxM1-ABCB1 Signaling Cascade

Over-expression of FSIP1 promotes breast cancer progression and confers resistance to docetaxel via MRP1 stabilization

(2019) Meisi Yan et al.   Cell Death & Disease

Advances in the systemic treatment of triple-negative breast cancer

(2018) J.M. Lebert et al.   Current Oncology

Corosolic acid induces cell cycle arrest and cell apoptosis in human retinoblastoma Y-79 cells via disruption of MELK-FoxM1 signaling

(2018) Ke Wang et al.   ONCOLOGY REPORTS

FOXM1 contributes to taxane resistance by regulating UHRF1-controlled cancer cell stemness

(2018) Bowen Yuan et al.   Cell Death & Disease

Genome-wide effects of MELK-inhibitor in triple-negative breast cancer cells indicate context-dependent response with p53 as a key determinant

(2017) Marisa Simon et al.   PLoS One

3D-QSAR studies on Maslinic acid analogs for Anticancer activity against Breast Cancer cell line MCF-7

(2017) Sarfaraz Alam et al.   Scientific Reports

Resensitization of Akt Induced Docetaxel Resistance in Breast Cancer by ‘Iturin A’ a Lipopeptide Molecule from Marine Bacteria Bacillus megaterium

(2017) Goutam Dey et al.   Scientific Reports

FoxM1 inhibition enhances chemosensitivity of docetaxel-resistant A549 cells to docetaxel via activation of JNK/mitochondrial pathway

(2016) Ke Wang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Triterpenes in cancer: significance and their influence

(2016) Balraj Singh Gill et al.   MOLECULAR BIOLOGY REPORTS

Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease

(2016) Giampaolo Bianchini et al.   Nature Reviews Clinical Oncology

Biology and Management of Patients With Triple-Negative Breast Cancer

(2016) P. Sharma   ONCOLOGIST

Pharmacokinetics, dynamics and toxicity of docetaxel: Why the Japanese dose differs from the Western dose

(2015) Hirotsugu Kenmotsu et al.   CANCER SCIENCE

Corosolic acid enhances 5-fluorouracil-induced apoptosis against SNU-620 human gastric carcinoma cells by inhibition of mammalian target of rapamycin

(2015) HYUN SU LEE et al.   Molecular Medicine Reports

Maslinic acid potentiates the antitumor activities of gemcitabine in vitro and in vivo by inhibiting NF-κB-mediated survival signaling pathways in human gallbladder cancer cells

(2015) YONG YU et al.   ONCOLOGY REPORTS

Corosolic Acid Exhibits Anti-angiogenic and Anti-lymphangiogenic Effects onIn VitroEndothelial Cells and on anIn VivoCT-26 Colon Carcinoma Animal Model

(2015) Ki Hyun Yoo et al.   PHYTOTHERAPY RESEARCH

Corosolic Acid Inhibits Hepatocellular Carcinoma Cell Migration by Targeting the VEGFR2/Src/FAK Pathway

(2015) Chung-Yu Ku et al.   PLoS One

EZH2 Protects Glioma Stem Cells from Radiation-Induced Cell Death in a MELK/FOXM1-Dependent Manner

(2015) Sung-Hak Kim et al.   Stem Cell Reports

Abstract 3039: The MELK/FOXM1 axis is a master regulator of proneural to mesenchymal transition (PMT) in glioma stem cells by controlling EZH2 transcriptional activity

(2015) Kaushal Joshi et al.   CANCER RESEARCH

Multiple mechanisms underlying acquired resistance to taxanes in selected docetaxel-resistant MCF-7 breast cancer cells

(2014) Harris Wang et al.   BMC CANCER

FOXM1 mediates resistance to docetaxel in gastric cancerviaup-regulating Stathmin

(2014) Xiaoxiao Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Oleanolic and maslinic acid sensitize soft tissue sarcoma cells to doxorubicin by inhibiting the multidrug resistance protein MRP-1, but not P-glycoprotein

(2014) Victor Hugo Villar et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Oleanane triterpenoids in the prevention and therapy of breast cancer: current evidence and future perspectives

(2014) Nisha R. Parikh et al.   PHYTOCHEMISTRY REVIEWS

Inhibitory effects of maslinic acid upon human esophagus, stomach and pancreatic cancer cells

(2014) Chun-che Lin et al.   Journal of Functional Foods

MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells

(2014) Yubao Wang et al.   eLife

Inhibition of ABCB1 Expression Overcomes Acquired Docetaxel Resistance in Prostate Cancer

(2013) Y. Zhu et al.   MOLECULAR CANCER THERAPEUTICS

MELK-Dependent FOXM1 Phosphorylation is Essential for Proliferation of Glioma Stem Cells

(2013) Kaushal Joshi et al.   STEM CELLS

FOXM1 mediates Dox resistance in breast cancer by enhancing DNA repair

(2012) Yun-Yong Park et al.   CARCINOGENESIS

Ursolic acid induces apoptosis by suppressing the expression of FoxM1 in MCF-7 human breast cancer cells

(2010) Jing-song Wang et al.   MEDICAL ONCOLOGY

Maslinic acid potentiates the anti-tumor activity of tumor necrosis factor α by inhibiting NF-κB signaling pathway

(2010) Chenghai Li et al.   Molecular Cancer

Maslinic acid, a natural triterpene from Olea europaea L., induces apoptosis in HT29 human colon-cancer cells via the mitochondrial apoptotic pathway

(2008) Fernando J. Reyes-Zurita et al.   CANCER LETTERS