Article
Oncology
Rui Song, Emily Riseberg, Joshua Petimar, Molin Wang, Lorelei A. Mucci, Kana Wu, Xuehong Zhang, Walter C. Willett, Edward L. Giovannucci, Stephanie A. Smith-Warner
Summary: The standardized scoring system for cancer prevention recommendations has been found to decrease cancer risk, while an alternative scoring system shows stronger associations in preventing cancer.
BRITISH JOURNAL OF CANCER
(2023)
Article
Nutrition & Dietetics
Iwona Hawrysz, Lidia Wadolowska, Malgorzata Anna Slowinska, Anna Czerwinska, Janusz Jacek Golota
Summary: This study examines the association between lung cancer risk in men and adherence to lung cancer prevention recommendations. The results suggest that limiting smoking and following comprehensive cancer prevention recommendations are associated with a lower risk of lung cancer in men.
Review
Nutrition & Dietetics
Daniele Nucci, Alessio Marino, Stefano Realdon, Mariateresa Nardi, Cristina Fatigoni, Vincenza Gianfredi
Summary: The systematic review focused on the rising incidence of esophageal adenocarcinoma (EAC) in developed countries and its associated risk factors, finding that body mass index and waist circumference were linked to increased EAC risk, while physical activity did not have a significant direct role in EAC risk. A diet rich in fruit, vegetables, and whole grains appeared to be more protective, while alcohol did not seem to be related to EAC, and smokers, especially heavy smokers, had an increased risk. Providing clear recommendations may help in preventing EAC.
Article
Nutrition & Dietetics
Antonella Mirizzi, Laura R. Aballay, Giovanni Misciagna, Maria G. Caruso, Caterina Bonfiglio, Paolo Sorino, Antonella Bianco, Angelo Campanella, Isabella Franco, Ritanna Curci, Filippo Procino, Anna M. Cisternino, Maria Notarnicola, Pierina F. D'Aprile, Alberto R. Osella
Summary: The study found that lifestyle measured by the modified mWCRF/AICR scoring system was negatively associated with mortality related to various diseases, especially in the male sub-cohort. The results suggest that adherence to a healthy diet can reduce the risk of mortality.
Review
Oncology
Fiona C. Malcomson, Christopher Wiggins, Solange Parra-Soto, Frederick K. Ho, Carlos Celis-Morales, Linda Sharp, John C. Mathers
Summary: A systematic review and meta-analysis found that strict adherence to the 2018 World Cancer Research Fund/American Institute for Cancer Research Cancer Prevention Recommendations is associated with a lower risk of breast, colorectal, and lung cancers. However, there is no significant association with prostate or other cancers. Further research is needed to explore the risk of other types of cancer.
Article
Oncology
Ane Sorlie Kvaerner, Astrid Riseth Andersen, Hege Berg Henriksen, Markus Dines Knudsen, Anne Marte Wetting Johansen, Anette Hjartaker, Siv Kjolsrud Bohn, Ingvild Paur, Gro Wiedswang, Sigbjorn Smeland, Trine B. Rounge, Rune Blomhoff, Paula Berstad
Summary: Adherence to the 2018 WCRF/AICR Score is associated with lower probability of screen-detected advanced precancerous lesions, but not CRC. The adherence to the recommendations concerning alcohol and BMI seems to be the most influential among the seven individual components included in the score.
Article
Nutrition & Dietetics
Emily B. Hill, Elizabeth M. Grainger, Gregory S. Young, Steven K. Clinton, Colleen K. Spees
Summary: This study examines the use of quantitative scoring criteria to assess changes among cancer survivors with overweight/obesity following an intensive behavioral intervention. The results show that participants improved adherence to all scored recommendations and there were significant improvements in BMI, waist circumference, and dietary habits. The updated scoring criteria can be applied to cancer survivor intervention studies and provide a tool for comparing the success of different interventions.
Article
Nutrition & Dietetics
Alice Zaramella, Diletta Arcidiacono, Daniele Nucci, Federico Fabris, Clara Benna, Salvatore Pucciarelli, Matteo Fassan, Alberto Fantin, Valli De Re, Renato Cannizzaro, Stefano Realdon
Summary: Esophageal adenocarcinoma (EAC) is a consequence of long-term gastroesophageal reflux, which leads to inflammation and could cause Barrett's esophagus (BE), the main risk factor for EAC development. The study aims to explore the esophageal microbial profile in patients with different stages of BE and EAC, and develop a score to predict cancer risk.
Article
Oncology
Virginia Lope, Angel Guerrero-Zotano, Emma Ruiz-Moreno, Begona Bermejo, Silvia Antolin, Alvaro Montano, Jose Manuel Baena-Canada, Manuel Ramos Vazquez, Nerea Fernandez de Larrea-Baz, Jose Ignacio Chacon, Jose Angel Garcia-Saenz, Clara Olier, Montserrat Munoz, Antonio Anton, Pedro Sanchez Rovira, Angels Arcusa Lanza, Sonia Gonzalez, Amparo Oltra, Joan Brunet, Joaquin Gavila Gregori, Maria Teresa Martinez, Lourdes Calvo, Libertad Rosell, Susana Bezares, Roberto Pastor-Barriuso, Beatriz Perez-Gomez, Miguel Martin, Marina Pollan
Summary: The study found that compliance with cancer prevention recommendations among breast cancer survivors is generally low, particularly in terms of limiting consumption of red/processed meats and high fiber intake. Compliance is worse among women with higher education levels and those with first-degree relatives with breast cancer. This information is helpful for designing personalized preventive measures.
Article
Public, Environmental & Occupational Health
Fiona C. Malcomson, Solange Parra-Soto, Liya Lu, Frederick Ho, Carlos Celis-Morales, Linda Sharp, John C. Mathers
Summary: The study investigated adherence to the 2018 WCRF/AICR Cancer Prevention Recommendations in the UK Biobank cohort and found significant variations in adherence across sociodemographic factors such as gender, age, education level, and ethnicity. Identifying and understanding lifestyle and dietary patterns according to sociodemographic factors could help in guiding public health strategies for the prevention of cancers and other non-communicable diseases.
JOURNAL OF PUBLIC HEALTH
(2023)
Article
Medicine, General & Internal
Fiona C. Malcomson, Solange Parra-Soto, Frederick K. Ho, Liya Lu, Carlos Celis-Morales, Linda Sharp, John C. Mathers
Summary: The study found that adherence to lifestyle recommendations was associated with a reduced risk of various cancers.
Article
Nutrition & Dietetics
Danielle D. B. Holthuijsen, Martijn J. L. Bours, Eline H. van Roekel, Stephanie O. Breukink, Maryska L. G. Janssen-Heijnen, Eric T. P. Keulen, Per M. Ueland, Oivind Midttun, Stefanie Brezina, Biljana Gigic, Andrea Gsur, Dieuwertje E. Kok, Jennifer Ose, Cornelia M. Ulrich, Matty P. Weijenberg, Simone J. P. M. Eussen
Summary: The adherence to dietary recommendations of the World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) and Dutch Healthy Diet (DHD) is associated with more favorable concentrations of kynurenines in colorectal cancer survivors.
Article
Gastroenterology & Hepatology
Yazan Abboud, Jamil S. Samaan, Janice Oh, Yi Jiang, Navkiran Randhawa, Daniel Lew, Jenan Ghaith, Pranav Pala, ChristineAnn Leyson, Rabindra Watson, Quin Liu, Kenneth Park, Shirley Paski, Arsen Osipov, Brent K. Larson, Andrew Hendifar, Katelyn Atkins, Nicholas N. Nissen, Debiao Li, Stephen J. Pandol, Simon K. Lo, Srinivas Gaddam
Summary: Younger women have shown an increasing incidence of pancreatic cancer, which has been externally validated nationwide. The rate of increase in incidence among younger women is significantly higher than among men, while there is no such trend among older adults.
Article
Pharmacology & Pharmacy
V Quagliariello, G. D'aiuto, R. Iaffaioli, M. Berretta, S. Buccolo, M. Iovine, A. Paccone, F. Cerrone, S. Bonanno, G. Nunnari, N. Lagana, G. Botti, N. Maurea
Summary: Following lifestyle recommendations from the World Cancer Research Fund and American Institute for Cancer Research may help prevent cardiovascular outcomes and acute respiratory distress syndrome in survivors post COVID-19 infection. The diet based on these recommendations could have beneficial metabolic effects through influencing pathways related to NLRP3 inflammasome-cytokine axis to improve prognosis, especially in cancer patients.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2021)
Article
Oncology
Marlou-Floor Kenkhuis, Floortje Mols, Eline H. van Roekel, Jose J. L. Breedveld-Peters, Stephanie O. Breukink, Maryska L. G. Janssen-Heijnen, Eric T. P. Keulen, Fraenzel J. B. van Duijnhoven, Matty P. Weijenberg, Martijn J. L. Bours
Summary: This study explores the adherence to World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) lifestyle recommendations in colorectal cancer (CRC) survivors and its impact on quality of life, fatigue, and chemotherapy-induced peripheral neuropathy (CIPN). The findings suggest that overall adherence to the recommendations benefits CRC survivors in terms of quality of life and fatigue, but not CIPN. However, specific recommendations have varying influences on these associations, necessitating further study.
Article
Gastroenterology & Hepatology
Guo-Chao Zhong, Wei-Ping Sun, Lun Wan, Jie-Jun Hu, Fa-Bao Hao
GASTROINTESTINAL ENDOSCOPY
(2020)
Article
Oncology
Guo-Chao Zhong, Jian-Yuan Pu, Yi-Lin Wu, Zhu-Jun Yi, Lun Wan, Kang Wang, Fa-Bao Hao, Yong Zhao, Jian-Ping Gong
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2020)
Article
Oncology
Guo-Chao Zhong, Yang Peng, Kang Wang, Lun Wan, You-Qi-Le Wu, Fa-Bao Hao, Jie-Jun Hu, Hai-Tao Gu
INTERNATIONAL JOURNAL OF CANCER
(2020)
Article
Respiratory System
Yang Peng, Guo-Chao Zhong, Lingxiao Wang, Lijuan Guan, Ao Wang, Kai Hu, Jing Shen
BMC PULMONARY MEDICINE
(2020)
Article
Cardiac & Cardiovascular Systems
Guo-Chao Zhong, Su-Qun Huang, Yang Peng, Lun Wan, You-Qi-Le Wu, Tian-Yang Hu, Jie-Jun Hu, Fa-Bao Hao
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2020)
Article
Oncology
Guo-Chao Zhong, Qu-Jin Li, Peng-Fei Yang, Yun-Bing Wang, Fa-Bao Hao, Kang Wang, Jie-Jun Hu, Jing-Jing Wu
Summary: Low-carbohydrate diets are associated with a reduced risk of pancreatic cancer, with age affecting this association, suggesting potential benefits for pancreatic cancer prevention.
Article
Oncology
Li-Wei Shi, Yi-Lin Wu, Jie-Jun Hu, Peng-Fei Yang, Wei-Ping Sun, Jian Gao, Kang Wang, Yang Peng, Jing-Jing Wu, Guo-Chao Zhong
Summary: This study found that higher dietary acid load is associated with a higher risk of pancreatic cancer, with a stronger association in subjects under 65 years old. Future studies should validate these findings in other populations.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2021)
Article
Nutrition & Dietetics
Guo-Chao Zhong, Hai-Tao Gu, Yang Peng, Kang Wang, You-Qi-Le Wu, Tian-Yang Hu, Feng-Chuang Jing, Fa-Bao Hao
Summary: The study found that high consumption of ultra-processed foods in the US population is associated with increased risks of cardiovascular mortality, especially in women. This suggests that the harmful effects of ultra-processed foods may have a stronger impact on cardiovascular health, particularly in female individuals.
INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY
(2021)
Article
Biochemistry & Molecular Biology
Guo-Chao Zhong, Zhi-Bo Zhao, Yao Cheng, Yun-Bing Wang, Chan Qiu, Lin-Hong Mao, Jie-Jun Hu, Dong Cai, Yan Liu, Jian-Ping Gong, Sheng-Wei Li
Summary: The study reveals that epigenetic silencing of GCH1 promotes HCC growth by inhibiting BH4 de novo biosynthesis, while BH4 metabolite inhibits HCC growth.
FREE RADICAL BIOLOGY AND MEDICINE
(2021)
Article
Oncology
Jiejun Hu, Dong Cai, Zhibo Zhao, Guo-Chao Zhong, Jianping Gong
Summary: HNRNPC plays a role in promoting proliferation, migration, and invasion of HCC cells, potentially through the Ras/MAPK signaling pathway. Therefore, HNRNPC may have a significant role in the progression of HCC and represents a promising biomarker for prognosis evaluation and a potential therapeutic target.
FRONTIERS IN ONCOLOGY
(2021)
Article
Cell Biology
Guo-Chao Zhong, Tian-Yang Hu, Peng-Fei Yang, Yang Peng, Jing-Jing Wu, Wei-Ping Sun, Long Cheng, Chun-Rui Wang
Summary: The study found that chocolate consumption is associated with reduced risks of mortality from all causes, cardiovascular disease, and Alzheimer's disease in the US population.
Article
Public, Environmental & Occupational Health
Chun-Rui Wang, Tian-Yang Hu, Fa-Bao Hao, Nan Chen, Yang Peng, Jing-Jing Wu, Peng-Fei Yang, Guo-Chao Zhong
Summary: The study aimed to examine the association between a type 2 diabetes-prevention diet and mortality in a US population. The results showed that adhering to this diet was associated with reduced risks of death from all causes, cardiovascular disease, and cancer.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Nutrition & Dietetics
Yan Huang, Feng Liu, A-Mei Chen, Peng-Fei Yang, Yang Peng, Jian-Ping Gong, Zhi Li, Guo-Chao Zhong
Summary: Adherence to a type 2 diabetes prevention diet is associated with a lower risk of pancreatic cancer in a US population. The study also suggests that the favorable association may be more pronounced in smokers. Further research is needed to confirm these findings.
CLINICAL NUTRITION
(2021)
Article
Cell Biology
Jie Yuan, Yang Peng, Fa-Bao Hao, Ya-Qin Wang, Chun-Rui Wang, Guo-Chao Zhong
Summary: The study found no significant difference in reducing HCC incidence among treatment-naive CHB patients between TDF and entecavir in both multivariable-adjusted and propensity-score-matched meta-analyses. The similarity of TDF to entecavir for HCC prevention persisted in studies with follow-up length of >= 4 years.