Review
Plant Sciences
Dongliang Liu, Xilu Wang, Hang Zhang
Summary: This study evaluated the efficacy and safety of gastrointestinal microbiome supplementation (GMS) for patients with allergic rhinitis (AR), and found that GMS resulted in better improvement in symptoms, quality of life, and medication scores compared to controls. However, GMS was less effective in reducing serum total IgE levels and the ratios of serum Th1/Th2. Overall, GMS yielded acceptable benefits for AR patients, although potential negative effects should be considered.
Review
Nutrition & Dietetics
Jenifer F. Kruger, Elaine Hillesheim, Amanda C. S. N. Pereira, Carolina Q. Camargo, Estela Rabito
Summary: Probiotic supplementation did not show significant benefits on cognitive function in individuals with dementia, but did improve certain metabolic markers. The current evidence is insufficient to support the clinical application of probiotics and synbiotics for individuals with dementia.
Review
Chemistry, Medicinal
Giuseppe Minervini, Rocco Franco, Maria Maddalena Marrapodi, Luca Fiorillo, Almir Badnjevic, Gabriele Cervino, Marco Cicciu
Summary: Mucositis refers to the inflammatory injury of the digestive tract's mucous membranes. Probiotics, as a promising therapeutic modality, have shown effectiveness in treating chemotherapy-induced mucositis for head and neck malignancies. This meta-analysis evaluated the efficiency of probiotics in this treatment by reviewing relevant studies published from 2000 to 31 January 2023. The analysis revealed that probiotics effectively reduced the severity of mucositis symptoms.
Review
Medicine, General & Internal
Anna Julia Elias, Viktoria Barna, Cristina Patoni, Dora Demeter, Daniel Sandor Veres, Stefania Bunduc, Balint Eross, Peter Hegyi, Laszlo Foldvari-Nagy, Katalin Lenti
Summary: This study systematically reviewed and meta-analyzed the effects of concurrent probiotic supplementation on gut microbiome composition during antibiotic therapy. The results showed that probiotic supplementation did not have a significant impact on gut microbiome diversity indices during antibiotic therapy. However, the limited number of studies and low sample sizes are the main limitations of this study, and further research is needed to determine appropriate microbiome diversity indices and their clinical relevance.
Review
Orthopedics
A. Bonato, M. Zenobi-Wong, G. Barreto, Z. Huang
Summary: This systematic review investigated the association between microbiota composition and osteoarthritis. The review identified certain bacteria that were upregulated in osteoarthritis subjects, as well as some bacteria associated with improved outcomes. However, the heterogeneity of methods and the lack of proper controls made it difficult to draw definitive conclusions about the causal link between microbiota and osteoarthritis.
OSTEOARTHRITIS AND CARTILAGE
(2022)
Review
Medicine, General & Internal
Xunshu Cheng, Haorui Wang, Zhihuang Zheng, Ke Feng, Saixue Tang, Yuanyuan Liu, Ke Chen, Chenhao Bi, Mingzhou Gao, Lijin Ji
Summary: This study aimed to investigate the relationship between different stages of Alzheimer disease and intestinal flora. The results showed a correlation between the abundance and diversity of flora and treatment efficacy. These findings are crucial for developing new strategies for the prevention and treatment of Alzheimer disease.
Review
Medicine, General & Internal
Long Huang, Qingsheng Yu, Hui Peng, Zhou Zhen
Summary: The gut microbiome in cirrhosis shows a decrease in the counts of Lactobacillus and Bifidobacterium, and an increase in the counts of Enterobacter and Enterococcus. Targeted supplementation of probiotics in cirrhosis, including Lactobacillus combined with Bifidobacterium or Bifidobacterium alone, can reduce blood ammonia levels and the incidence of hepatic encephalopathy.
Review
Neurosciences
Arden L. McMath, Miriam Aguilar-Lopez, Corinne N. Cannavale, Naiman A. Khan, Sharon M. Donovan
Summary: Evidence from animal models or children with neurodevelopmental disorders suggests a link between the gut microbiome and neurocognitive development. This study aimed to identify consistent gut microbiome characteristics associated with cognitive outcomes in healthy infants and children. After analyzing 1,520 articles, 23 were included and showed that Bifidobacterium, Bacteroides, Clostridia, Prevotella, and Roseburia were related to aspects of cognition. However, further studies focusing on more complex cognition are needed to fully understand the role of the gut microbiome in cognitive development.
FRONTIERS IN NEUROSCIENCE
(2023)
Review
Nutrition & Dietetics
Chengting Chang, Xingzhu Yuan, Xingxia Zhang, Xinrong Chen, Ka Li
Summary: The gastrointestinal microbiome is associated with various health outcomes, and current interventions are generally safe and beneficial. However, the quality of evidence is not high, and more randomized controlled trials are needed.
Review
Biology
Clarissa Reginato Taufer, Pabulo Henrique Rampelotto
Summary: Studies have found that Bifidobacterium may provide protection against COVID-19 by reducing symptoms, improving lung function, reducing inflammation, and alleviating gastrointestinal symptoms. The genus may also modulate the immune response, compete with pathogenic microbes, and maintain gut barrier function to combat the disease.
Article
Veterinary Sciences
Karin Allenspach, Chi-Hsuan Sung, Jose Joaquin Ceron, Camila Peres Rubio, Agnes Bourgois-Mochel, Jan S. Suchodolski, Lingnan Yuan, Debosmita Kundu, Joan Colom Comas, Kieran Rea, Jonathan P. Mochel
Summary: This study investigated the effects of DE-CA9 (TM) on healthy Beagle dogs and found that it can reduce oxidative stress markers and have positive effects on protein and lipid metabolism in serum and feces.
VETERINARY SCIENCES
(2023)
Article
Biotechnology & Applied Microbiology
Ingrid Maria Cecilia Rubin, Sarah Mollerup, Christa Broholm, Adam Baker, Mona Katrine Alberthe Holm, Martin Schou Pedersen, Mette Pinholt, Henrik Westh, Andreas Munk Petersen
Summary: This study investigates the potential of synbiotic intervention with probiotics and prebiotic fiber in healthy volunteers and tracks the changes in the ingested probiotic strain. The results show that there are no significant changes in the gut microbiome after the intervention, but the abundance of probiotics increases and the probiotic strain can be detected in fecal samples.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2022)
Review
Nutrition & Dietetics
Lana Kairey, Bradley Leech, Fatima El-Assaad, Andrea Bugarcic, Drew Dawson, Romy Lauche
Summary: Fermented-milk kefir may have potential health benefits, such as reducing the risk of dental caries, eradicating Helicobacter pylori, and aiding in the treatment of adult dyslipidemia and hypertension. However, the available evidence is limited, and more high-quality human trials are needed to determine its efficacy and safety.
Review
Nutrition & Dietetics
Gholamreza Askari, Abed Ghavami, Farnaz Shahdadian, Amir Reza Moravejolahkami
Summary: The study found that supplementation with synbiotics and probiotics has a significant effect on certain inflammatory and oxidative stress markers, but further research is needed to confirm these findings.
CLINICAL NUTRITION
(2021)
Article
Chemistry, Multidisciplinary
Marjorie T. Buss, Pradeep Ramesh, Max Atticus English, Audrey Lee-Gosselin, Mikhail G. Shapiro
Summary: The use of a composite biomagnetic material with microscale magnetic particles and probiotic bacteria, along with an externally applied magnetic field, allows for better localization and retention of probiotic bacteria in the GI tract of mice. This technology enhances the ability of GI-targeted probiotics to accumulate at specific locations and stably colonize without the need for antibiotic treatment, providing external physical control to an important class of microbial theranostics.
ADVANCED MATERIALS
(2021)