Article
Medicine, General & Internal
Tobias F. S. Pustjens, Marijke J. C. Timmermans, Saman Rasoul, Arnoud W. J. van't Hof
Summary: The study found that NSTE-ACS patients with MVD undergoing MV-PCI and CO-PCI had similar mortality rates at long-term follow-up, but the MV-PCI group showed improved event-free survival in terms of fewer coronary reinterventions.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Jangho Park, Sangwoo Park, Yong-Giun Kim, Soe Hee Ann, Hyun Woo Park, Jon Suh, Jae-Hyung Roh, Young-Rak Cho, Seungbong Han, Gyung-Min Park
Summary: An analysis of National Health Insurance data in Korea showed that pre-existing depression does not have a significant impact on mortality in patients with established coronary artery disease undergoing PCI. However, younger patients with angina and depression may have a higher risk of all-cause mortality.
SCIENTIFIC REPORTS
(2021)
Article
Cardiac & Cardiovascular Systems
J. Hunter Mehaffey, J. W. Awori Hayanga, Mohammad Kawsara, Ankit Sakhuja, Christopher Mascio, J. Scott Rankin, Vinay Badhwar
Summary: Contemporary real-world data from Medicare patients with multivessel disease reveal that coronary artery bypass grafting (CABG) outcomes were superior to percutaneous coronary intervention (PCI), providing important longitudinal data to guide patient care and policy development.
ANNALS OF THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Shen Lin, Changdong Guan, Fan Wu, Lihua Xie, Tongqiang Zou, Yanpu Shi, Sipeng Chen, Li He, Bo Xu, Zhe Zheng
Summary: In patients with chronic total occlusion and multivessel disease, percutaneous coronary intervention (PCI) has a higher risk of 5-year composite death, myocardial infarction, or stroke compared to coronary artery bypass grafting (CABG). This difference is particularly significant in patients recommended for CABG according to the SYNTAX score.
CIRCULATION-CARDIOVASCULAR INTERVENTIONS
(2022)
Review
Cardiac & Cardiovascular Systems
Yujia Feng, Shu Li, Sihan Hu, Jing Wan, Hua Shao
Summary: This study suggests that complete revascularization should be performed in STEMI patients with multivessel coronary artery disease, and complete revascularization at the index procedure is superior to staged revascularization in reducing the risk of MACE events.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Medical Laboratory Technology
Fabio Angeli, Paolo Verdecchia, Stefano Savonitto, Sara Cavallini, Andrea Santucci, Stefano Coiro, Rocco Sclafani, Clara Riccini, Stefano De Servi, Claudio Cavallini
Summary: This study found that higher levels of sCD40L predict an increased risk of acute coronary events and coronary restenosis among patients with ACS or CCS undergoing PCI, but not of mortality.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2022)
Article
Medicine, General & Internal
Claudio Montalto, Nuccia Morici, Aung Myat, Gabriele Crimi, Giuseppe De Luca, Irene Bossi, Adam de Belder, Stefano Savonitto, Stefano De Servi
Summary: In older adults with acute myocardial infarction, a strategy of multi-vessel percutaneous coronary intervention (MV-PCI) for complete revascularization is associated with better survival and lower risk of adverse clinical events compared to a strategy of culprit-vessel (CV) PCI.
EUROPEAN JOURNAL OF INTERNAL MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Denise Cristiana Faro, Claudio Laudani, Federica Giuseppa Agnello, Nicola Ammirabile, Simone Finocchiaro, Marco Legnazzi, Maria Sara Mauro, Placido Maria Mazzone, Giovanni Occhipinti, Carla Rochira, Lorenzo Scalia, Marco Spagnolo, Antonio Greco, Davide Capodanno
Summary: Multivessel disease (MVD) is common in patients with acute coronary syndromes (ACS) and is associated with poor outcomes and high mortality rates. Complete revascularization is beneficial for hemodynamically stable ACS patients with MVD, but there are still uncertainties regarding optimal timing and guidance strategies.
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Review
Cardiac & Cardiovascular Systems
Nicholas W. S. Chew, Jin Hean Koh, Cheng Han Ng, Darren Jun Hao Tan, Jie Ning Yong, Chaoxing Lin, Oliver Zi-Hern Lim, Yip Han Chin, Denzel Ming Wei Lim, Koo Hui Chan, Poay-Huan Loh, Adrian Low, Chi-Hang Lee, Huay-Cheem Tan, Mark Chan
Summary: This study conducted a two-stage meta-analysis using reconstructed individual patient data to compare long-term mortality between coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) for patients with multivessel disease (MVD) without left main (LM) involvement. The results showed that CABG had a lower cumulative all-cause mortality compared to PCI for MVD patients without LM involvement. However, in patients with moderate to high SYNTAX score, PCI had a significantly higher 10-year all-cause mortality compared to CABG.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Cell Biology
Bradley Tucker, Kaivan Vaidya, Blake J. Cochran, Sanjay Patel
Summary: Periprocedural myocardial injury and myocardial infarction are common complications of percutaneous coronary intervention, associated with increased short- and long-term mortality. Inflammation levels before, during, and after the procedure are linked to higher rates of myonecrosis and future cardiovascular events. In addition to inflammation from underlying coronary disease, PCI itself triggers an acute inflammatory response.
Article
Cardiac & Cardiovascular Systems
Jiachun Lang, Chen Wang, Le Wang, Jingxia Zhang, Yuecheng Hu, Huajun Sun, Hongliang Cong, Yin Liu
Summary: Staged PCI is superior to culprit-only PCI in elderly patients with STEMI and MVD.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Fernando Alfonso, Cristina Fernandez-Perez, Nayade del Prado, Marcos Garcia-Guimaraes, Jose Luis Bernal, Teresa Bastante, David del Val, Nicolas Rosillo, Javier Elola
Summary: This study compared in-hospital mortality and 30-day readmission rates between patients with spontaneous coronary artery dissection (SCAD) and ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PPCI) and patients with STEMI without SCAD undergoing PPCI. The results showed that PPCI, when indicated in patients with STEMI and SCAD, has similar in-hospital mortality and 30-day readmission rates compared with PPCI for atherothrombotic STEMI. These findings support the value of PPCI in selected patients with SCAD.
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Medicine, General & Internal
Casper W. H. Beijnink, Troels Thim, Dirk Jan van der Heijden, Igor Klem, Rasha Al-Lamee, Jacqueline L. Vos, Yvonne Koop, Marcel G. W. Dijkgraaf, Marcel A. M. Beijk, Raymond J. Kim, Justin Davies, Luis Raposo, Sergio B. Baptista, Javier Escaned, Jan J. Piek, Michael Maeng, Niels van Royen, Robin Nijveldt
Summary: The study aims to investigate the optimal timing for non-culprit lesion revascularisation in STEMI patients and includes a 12-month follow-up with cost-effectiveness analysis. The results will be shared in multiple articles, with potential for subgroup analyses or spin-off studies.
Article
Cardiac & Cardiovascular Systems
Jorge Salamanca, Marcos Garcia-Guimaraes, Manel Sabate, Ricardo Sanz-Ruiz, Fernando Macaya, Gerard Roura, Marcelo Jimenez-Kockar, Juan Manuel Nogales, Helena Tizon-Marcos, Maite Velazquez-Martin, Gabriela Veiga, Santiago Camacho-Freire, Ainhoa Perez-Guerrero, Xacobe Flores-Rios, Teresa Alvarado, Pablo Diez-Villanueva, David Del Val, Teresa Bastante, Fernando Alfonso
Summary: This study analyzed data from 389 consecutive patients and found that 10.5% of patients had multivessel spontaneous coronary artery dissection (SCAD), which was associated with a worse prognosis compared to single-vessel SCAD. Multivessel SCAD patients were more often associated with hypothyroidism and anxiety disorder, presented more frequently as non-ST segment elevation myocardial infarction, and showed different angiographic features compared to single-vessel SCAD patients. The composite clinical outcomes were similar between the two groups, but the rate of stroke was significantly higher in multivessel SCAD patients.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Medicine, General & Internal
Ada del Mar Carmona-Segovia, Maria Victoria Doncel-Abad, Victor M. Becerra-Munoz, Jorge Rodriguez-Capitan, Fernando Sabatel-Perez, Maria Flores-Lopez, Maria Jose Sanchez-Quintero, Dina Medina-Vera, Ana Isabel Molina-Ramos, Rajaa El Bekay, Jose Miguel Morales-Asencio, Maria Angullo-Gomez, Luis Garcia-Rodriguez, Lucia Palma-Marti, Francisco Javier Pavon-Moron, Manuel F. Jimenez-Navarro
Summary: This study aims to evaluate changes of clinical and biochemical parameters in older patients with multivessel coronary artery disease (MVCAD) undergoing revascularisation and to establish a prognostic stratification model for complete revascularization (CR) and incomplete revascularization (ICR).
Article
Cardiac & Cardiovascular Systems
Jung-Joon Cha, SungA Bae, Duk-Woo Park, Jae Hyoung Park, Soon Jun Hong, Seong-Mi Park, Cheol Woong Yu, Seung-Woon Rha, Do-Sun Lim, Soon Yong Suh, Seung Hwan Han, Seong-Ill Woo, Nae-Hee Lee, Donghoon Choi, In-Ho Chae, Hyo-Soo Kim, Young Joon Hong, Youngkeun Ahn, Myung Ho Jeong, Tae Hoon Ahn
Summary: The study found an association between prehospital delay and clinical outcomes in NSTEMI patients, with prehospital delay being related to an increased risk of 3-year all-cause mortality. Factors predicting prehospital delay included age, gender, type of symptoms, diabetes, and use of emergency medical services.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Yongcheol Kim, SungA Bae, Thomas W. Johnson, Nak-Hoon Son, Doo Sun Sim, Young Joon Hong, Sang Wook Kim, Deok-Kyu Cho, Jung-Sun Kim, Byeong-Keuk Kim, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang, Myung Ho Jeong
Summary: In patients with acute myocardial infarction undergoing PCI with second-generation drug-eluting stent implantation, the use of IVUS guidance is associated with a significant reduction in 3-year target lesion failure, mainly driven by lower risk of cardiac death and target vessel myocardial infarction.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Cardiac & Cardiovascular Systems
Yongwhan Lim, Min Chul Kim, Youngkeun Ahn, Kyung Hoon Cho, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Myung Ho Jeong, Sang Hong Baek, Sung-Ho Her, Kwan Yong Lee, Seung Hwan Han, Seung-Woon Rha, Dong-Ju Choi, Hyeon-Cheol Gwon, Hyuck Moon Kwon, Tae-Hyun Yang, Keun-Ho Park, Sang-Ho Jo
Summary: This study investigated the prognostic impact of long-acting vasodilator therapy in patients with vasospastic angina. The results showed that the use of nitrate-based medications was associated with an increased risk of acute coronary syndrome within 2 years, especially in low-risk patients.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Medicine, General & Internal
Seok Oh, Ju Han Kim, Kyung Hoon Cho, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Youngkeun Ahn, Myung Ho Jeong
Summary: This study found that the long-term clinical outcomes were similar in patients with Killip III-IV AMI who underwent PCI during off-hours and on-hours.
KOREAN JOURNAL OF INTERNAL MEDICINE
(2022)
Article
Medicine, General & Internal
Seok Oh, Myung Ho Jeong, Kyung Hoon Cho, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Youngkeun Ahn
Summary: This study compared the clinical outcomes of PCI versus medical therapy in nonagenarian Korean patients with AMI, and found that nonagenarian patients with AMI undergoing PCI had better clinical outcomes. Further research is needed to determine the benefits of PCI for this population.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Kyung Hoon Cho, Min Chul Kim, Eun Ho Choo, Ik Jun Choi, Su Nam Lee, Mahn-Won Park, Chul Soo Park, Hee-Yeol Kim, Chan Joon Kim, Doo Sun Sim, Ju Han Kim, Young Joon Hong, Myung Ho Jeong, Kiyuk Chang, Youngkeun Ahn
Summary: This study aimed to explore the relationship between low baseline LDL-C levels and long-term cardiovascular events after discharge in patients with acute coronary syndrome. The results showed that low baseline LDL-C levels were associated with an increased risk of cardiovascular events.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Medicine, General & Internal
Seok Oh, Ju Han Kim, Kyung Hoon Cho, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Youngkeun Ahn, Myung Ho Jeong
Summary: This study aimed to compare the clinical outcomes of patients with acute myocardial infarction with renal impairment (AMI-RI) treated with ACEIs or ARBs in real-world clinical settings. The results showed that treatment with ACEIs seemed to be more beneficial, with lower rates of major adverse cardiac and cerebrovascular events, compared to treatment with ARBs. Further prospective studies are required to confirm these findings.
MAYO CLINIC PROCEEDINGS
(2023)
Article
Cardiac & Cardiovascular Systems
Kyung Hoon Cho, Min-Ho Shin, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Youngkeun Ahn, Hyo-Soo Kim, Seung-Ho Hur, Sang Rok Lee, Jin-Yong Hwang, Seok Kyu Oh, Kwang Soo Cha, Myung Ho Jeong
Summary: Data analysis from KAMIR showed that misdiagnosis of STEMI is not rare and is associated with a significant delay in coronary angiography, leading to increased 1-year mortality for patients with culprit lesions in the left anterior descending artery.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Review
Peripheral Vascular Disease
Hack-Lyoung Kim, Eun Mi Lee, Shin Young Ahn, Kwang-il Kim, Hyeon Chang Kim, Ju Han Kim, Hae-Young Lee, Jang Hoon Lee, Jong-Moo Park, Eun Joo Cho, Sungha Park, Jinho Shin, Young-Kwon Kim
Summary: This review provides an update on the 2018 Korean Hypertension Society Guidelines for the management of hypertension. It highlights the importance of ambulatory and home blood pressure monitoring for diagnosis and treatment target determination. The updated guidelines recommend a target blood pressure below 130/80 mmHg for high-risk patients based on consensus and the SPRINT study. However, for conditions such as cerebral infarction and chronic kidney disease, as well as for elderly patients, the target blood pressure is generally set at <140/90 mmHg due to lack of evidence.
CLINICAL HYPERTENSION
(2023)
Article
Cardiac & Cardiovascular Systems
Min Chul Kim, Yongwhan Lim, Seung Hun Lee, Yoonmin Shin, Joon Ho Ahn, Dae Young Hyun, Kyung Hoon Cho, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Myung Ho Jeong, Yong Hun Jung, In-Seok Jeong, Youngkeun Ahn
Summary: This study investigated whether early routine left ventricular unloading can reduce 30-day mortality compared with the conventional approach in patients with cardiogenic shock undergoing VA-ECMO. The results showed no significant difference in reducing 30-day mortality between early routine left ventricular unloading and the conventional approach.
Article
Medicine, General & Internal
Joon Sung Park, Kyung Hoon Cho, Young Joon Hong, Min Chul Kim, Doo Sun Sim, Ju Han Kim, Youngkeun Ahn, Myung Ho Jeong
Summary: The prognostic impact of baseline lipoprotein(a) levels on long-term clinical outcomes among patients with acute myocardial infarction remains unclear. A study on Korean patients with acute myocardial infarction showed that different baseline lipoprotein(a) levels did not independently associate with an increased incidence of three-point major adverse cardiovascular events at 3 years.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2023)
Review
Peripheral Vascular Disease
Sang-Hyun Ihm, Jae-Hyeong Park, Jang Young Kim, Ju-Han Kim, Kwang-Il Kim, Eun Mi Lee, Hae-Young Lee, Sungha Park, Jinho Shin, Cheol-Ho Kim
Summary: Home blood pressure measurement (HBPM) is advantageous in diagnosing and treating various issues related to hypertension and has shown better predictive values in cardiovascular morbidity and mortality than office blood pressure monitoring.
CLINICAL HYPERTENSION
(2022)
Article
Medicine, General & Internal
Seok Oh, Ju Han Kim, Kyung Hoon Cho, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Youngkeun Ahn, Myung Ho Jeong
Summary: Pulmonary hypertension may be associated with the development of new-onset heart failure and cardiogenic shock in AMI+COPD patients, and it may also be related to all-cause mortality.