Article
Biochemical Research Methods
Maissa Dardouri, Rita M. Mendes, Johannes Frenzel, Judite Costa, Isabel A. C. Ribeiro
Summary: This study aimed to develop improved methodologies for the identification, separation, and purification of sophorolipids and rhamnolipids. Using modified UHPLC-MS/MS method and novel reversed-phase solid-phase extraction methods, sophorolipids and rhamnolipids were successfully identified and purified with purity of 94% and 99% respectively, facilitating further studies on their individual properties.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Review
Biochemistry & Molecular Biology
Simms A. Adu, Matthew S. Twigg, Patrick J. Naughton, Roger Marchant, Ibrahim M. Banat
Summary: The use of glycolipid biosurfactants in industrial applications has increased significantly in the 21st century. In the skincare industry, these biosurfactants have shown potential as natural and sustainable alternatives to synthetic surfactants. However, there are still several barriers to their widespread adoption.
Article
Chemistry, Physical
Rishi Devendra Singh, Neela Gayathri Ganesan, Vivek Rangarajan
Summary: This study focuses on formulating a stable nanoemulsion system using a combination of plant-derived surfactant (Quillaja saponin) and microbial-derived surfactant (surfactin), with coconut oil as the base oil. Sample 6 from cluster 5 has been identified as the best-performing sample, with a mean droplet size of 173 nm, polydispersity index of 0.195, and zeta potential of -65 mV. Stability analysis has confirmed the stability of this sample.
Review
Chemistry, Applied
Olivia Eskens, Samiul Amin
Summary: Epidermal growth factors have shown promising results in skincare treatments, but their incorporation into skincare formulations is hindered by challenges such as low transdermal delivery efficacy, material interactions, and protein instability. Optimizing the stability and synergy of growth factor products is crucial for enhancing skincare effects. New drug delivery systems are being explored to overcome the challenges of topical growth factor treatment, emphasizing the importance of considering all components in a formulation simultaneously for engineering an optimal cosmeceutical product.
INTERNATIONAL JOURNAL OF COSMETIC SCIENCE
(2021)
Article
Chemistry, Applied
Rose Maxwell, Marius C. Costache, Abigail Giarrosso, Carlos Bosques, Samiul Amin
Summary: Silk fibroin in combination with capryl glucoside exhibits synergistic surface-active behavior, resulting in a natural and effective co-surfactant system with superior surface tension properties compared to synthetic surfactants. This system enhances foam quality and cleansing properties, making it ideal for formulating cleansers and shampoos.
INTERNATIONAL JOURNAL OF COSMETIC SCIENCE
(2021)
Article
Chemistry, Applied
Adeline Maria Benhur, Jangelis Diaz, Samiul Amin
Summary: The addition of Merquat increases the viscosity and viscoelastic properties of the SLES-CapB-Merquat system due to electrostatic interactions. The presence of salt significantly impacts the system's rheological response. Wet combing force data shows that the charged polyelectrolyte binds to the hair substrate, resulting in reduced combing force values. The addition of silicone oil enhances the conditioning effect of the formulation.
INTERNATIONAL JOURNAL OF COSMETIC SCIENCE
(2021)
Article
Chemistry, Applied
Omolade M. Ajayi, Samiul Amin
Summary: The study explored the performance effects of fumed silica and cornstarch as alternatives to talc in cosmetic powder formulations. Results showed that the concentration of additives influences the performance of cosmetic powder formulations. Fumed silica demonstrated better compressibility and flow effects compared to cornstarch.
INTERNATIONAL JOURNAL OF COSMETIC SCIENCE
(2021)
Article
Chemistry, Physical
Jordan Hirschman, Deepika Venkataramani, Markela Ibo Murphy, Sajal M. Patel, Jiali Du, Samiul Amin
Summary: The study developed a thin gap methodology on a mechanical rheometer to characterize high concentration monoclonal antibody formulations, aiming to reduce sample volume requirement and provide viscosity data over a wide shear rate range, which is crucial for biopharmaceutical formulation research at early stages. The gap-dependent changes in rheological behavior and the impact of surfactants and excipients on high shear rate viscosity were investigated, showing interesting shear thinning and shear thickening phenomena at different shear rates and gap sizes. The diffusion interaction parameter kD was found to be indicative of the high shear rate viscosity behavior of these formulations.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Chemistry, Applied
Sarah Speer, Samiul Amin
Summary: In this study, the use of biopolymers whey protein and chitosan in creating a thermoresponsive emulsion was investigated. The impact of chitosan inclusion and specific oils on rheological properties and temperature response was studied. Results showed that an emulsion with 15 wt. % WP, 10 wt. % jojoba oil, and 0.5 wt. % chitosan exhibited the strongest structural response to temperature.
INTERNATIONAL JOURNAL OF COSMETIC SCIENCE
(2022)
Article
Chemistry, Applied
Kelly Yorke, Andrei Potanin, Suzanne Jogun, Andre Morgan, Hongwei Shen, Samiul Amin
Summary: The study found that the AOS and Sultaine system at a ratio of 1:1 exhibited the best surface activity and foaming properties. Additionally, the addition of APG increased surface tension, while the concentration of salt had a certain effect on surface tension.
INTERNATIONAL JOURNAL OF COSMETIC SCIENCE
(2021)
Article
Chemistry, Applied
Mackenzie Kolman, Connor Smith, Debojit Chakrabarty, Samiul Amin
Summary: This paper aims to analyze the rheological changes and dynamics of Carbopol gel systems over time, specifically neutralized by triethanol amine, to understand the time stabilities and ageing effects. The study observed significant differences in viscosity and modulus values among water-based, ethanol-based, and isopropyl alcohol-based gels, shedding light on the microstructural evolution of such gel systems. The results indicated that ethanol and water-based gels showed relatively stable rheological behavior over 30 days, while the isopropyl alcohol-based gel exhibited a significant increase in viscosity, suggesting different ageing mechanisms in these systems.
INTERNATIONAL JOURNAL OF COSMETIC SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Tatiana Andrea Perea Cubides, Samiul Amin
Summary: Deposition is crucial for the delivery and efficiency of hair and skin formulations by allowing active compounds to interact with surfaces. This study focuses on the surfactants and conditioning agents used in conditioning shampoos and examines their deposition on hair and scalp. Varying cationic polymer and salt fractions, eighteen different shampoo formulations were tested for deposition using nanoplasmonic sensing technology. The wet combing test was conducted to explore the correlation between combing force and surface deposition. Sustainable anionic surfactants were used for comparison with traditional formulations.
Article
Biochemistry & Molecular Biology
Meghan Hartson, Ciara Coyle, Samiul Amin
Summary: Methylcellulose and chitosan are promising ingredients for a thermoresponsive hair styling gel, which have been successfully applied in the medical industry. These ingredients uphold the clean beauty standard and do not compromise on performance. By combining them, a hair gel can be created that provides an extended hold of style when heat is applied. Chitosan acts as a cationic biopolymer to adhere the gel to the hair, while methylcellulose acts as a smart biopolymer to lock the desired hairstyle in place.
Article
Biochemistry & Molecular Biology
Mackenzie Kolman, Gregory Boland, Samiul Amin
Summary: Diffusing wave spectroscopy is a potential solution for quickly identifying instability in cosmetic formulations, with the study showing that larger changes in mean square displacement values over a 3-hour period indicating greater instability in emulsions. Further research is needed to explore DWS as a vital emulsion instability detector in a wider range of formulations.
Article
Biochemistry & Molecular Biology
Omolade Ajayi, Aina Davies, Samiul Amin
Summary: This study aimed to evaluate the performance of a novel cationic amino lipid surfactant compared to conventional surfactants in hair conditioner formulations. Results showed that higher shear mixing rates during formulation lead to poorer performance effects, such as decreased yield stress values, lower percentage reduction in combing force, and a higher coefficient of friction.
Article
Biochemistry & Molecular Biology
Kelly Yorke, Samiul Amin
Summary: Consumers are increasingly interested in natural and sustainable ingredients in personal care products. This study aimed to find a sustainable formulation for conditioning shampoo without compromising performance. By using hyaluronic acid at different molecular weights and concentrations, along with surfactants and sodium chloride, researchers were able to achieve lower wet combing force, ideal rheological properties, and reduced surface tension.
Article
Biochemistry & Molecular Biology
Olivia Eskens, Gianna Villani, Samiul Amin
Summary: An alginate-methylcellulose gel system offers superior viscosity and thermoresponsiveness compared to individual components, with increased methylcellulose concentration enhancing gel elasticity and providing better thermal protection of EGF. EGF concentration plays a significant role in the shear viscosity and thermoresponsiveness of the ternary system. This system shows promising rheological tunability for providing EGF thermal protection in topical delivery.