Does the human placenta express the canonical cell entry mediators for SARS-CoV-2?

Coronavirus Disease 2019 (COVID-19) and Pregnancy: What obstetricians need to know

(2020) Sonja A. Rasmussen et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records

(2020) Huijun Chen et al.   LANCET

An interactive web-based dashboard to track COVID-19 in real time

(2020) Ensheng Dong et al.   LANCET INFECTIOUS DISEASES

Clinical Characteristics of 46 Pregnant Women with a SARS-CoV-2 Infection in Washington State

(2020) Erica M. Lokken et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Pregnant vs nonpregnant severe acute respiratory syndrome coronavirus 2 and coronavirus disease 2019 hospital admissions: the first 4 weeks in New York

(2020) Asma Tekbali et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Evidence for and against vertical transmission for SARS-CoV-2 (COVID-19)

(2020) A. Lamouroux et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Care of the pregnant woman with coronavirus disease 2019 in labor and delivery: anesthesia, emergency cesarean delivery, differential diagnosis in the acutely ill parturient, care of the newborn, and protection of the healthcare personnel

(2020) Balakrishnan Ashokka et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Coronavirus disease 2019 during pregnancy: a systematic review of reported cases

(2020) Anna Nunzia Della Gatta et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Coronavirus disease 2019 pandemic: staged management of surgical services for gynecology and obstetrics

(2020) Emily E. Weber LeBrun et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Screening all pregnant women admitted to labor and delivery for the virus responsible for coronavirus disease 2019

(2020) William S. Vintzileos et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Coronavirus disease 2019 in pregnant women: a report based on 116 cases

(2020) Jie Yan et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Maternal death due to COVID-19

(2020) Sedigheh Hantoushzadeh et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Severe COVID-19 during Pregnancy and Possible Vertical Transmission

(2020) Maria Claudia Alzamora et al.   AMERICAN JOURNAL OF PERINATOLOGY

Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2

(2020) Qihui Wang et al.   CELL

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

SARS ‐CoV‐2 receptor ACE 2 and TMPRSS 2 are primarily expressed in bronchial transient secretory cells

(2020) Soeren Lukassen et al.   EMBO JOURNAL

Antibodies in Infants Born to Mothers With COVID-19 Pneumonia

(2020) Hui Zeng et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn

(2020) Lan Dong et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Baby’s First Macrophage: Temporal Regulation of Hofbauer Cell Phenotype Influences Ligand-Mediated Innate Immune Responses across Gestation

(2020) Dominika Swieboda et al.   JOURNAL OF IMMUNOLOGY

Clinical manifestations and outcome of SARS-CoV-2 infection during pregnancy

(2020) Yangli Liu et al.   JOURNAL OF INFECTION

Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study

(2020) Nan Yu et al.   LANCET INFECTIOUS DISEASES

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

(2020) David E. Gordon et al.   NATURE

Structural basis of receptor recognition by SARS-CoV-2

(2020) Jian Shang et al.   NATURE

Lack of maternal–fetal SARS-CoV-2 transmission

(2020) Hannah Stower   NATURE MEDICINE

SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

(2020) Waradon Sungnak et al.   NATURE MEDICINE

Universal Screening for SARS-CoV-2 in Women Admitted for Delivery

(2020) Desmond Sutton et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical Characteristics of Pregnant Women with Covid-19 in Wuhan, China

(2020) Lian Chen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Placental transfer of Letermovir & Maribavir in the ex vivo human cotyledon perfusion model. New perspectives for in utero treatment of congenital cytomegalovirus infection

(2020) Valentine Faure Bardon et al.   PLoS One

Preterm delivery in pregnant woman with critical COVID ‐19 pneumonia and vertical transmission

(2020) Marzieh Zamaniyan et al.   PRENATAL DIAGNOSIS

Neonatal Early-Onset Infection With SARS-CoV-2 in 33 Neonates Born to Mothers With COVID-19 in Wuhan, China

(2020) Lingkong Zeng et al.   JAMA Pediatrics

Infants Born to Mothers With a New Coronavirus (COVID-19)

(2020) Yan Chen et al.   Frontiers in Pediatrics

Maternal mortality among women with coronavirus disease 2019 admitted to the intensive care unit

(2020) Matthew J. Blitz et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Coronavirus disease 2019 (COVID-19) pandemic and pregnancy

(2020) Pradip Dashraath et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Renin-angiotensin-aldosterone system and COVID-19 infection

(2020) Joachim Alexandre et al.   ANNALES D ENDOCRINOLOGIE

SARS-COV-2 Maternal–Child Transmission

(2020) George K. Siberry et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

SARS–CoV-2 infection of the placenta

(2020) Hillary Hosier et al.   JOURNAL OF CLINICAL INVESTIGATION

TMPRSS2 contributes to virus spread and immunopathology in the airways of murine models after coronavirus infection

(2019) Naoko Iwata-Yoshikawa et al.   JOURNAL OF VIROLOGY

Viral receptors for flaviviruses: Not only gatekeepers

(2019) Lilian G. Oliveira et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Envelope Protein Glycosylation Mediates Zika Virus Pathogenesis

(2019) Derek L. Carbaugh et al.   JOURNAL OF VIROLOGY

The fetal origins of mental illness

(2019) Benjamin J.S. al-Haddad et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Safety and varicella outcomes after varicella zoster immune globulin administration in pregnancy

(2019) Geeta K. Swamy et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

CD46 facilitates entry and dissemination of human cytomegalovirus

(2019) Kathryn R. Stein et al.   Nature Communications

Fast, sensitive and accurate integration of single-cell data with Harmony

(2019) Ilya Korsunsky et al.   NATURE METHODS

Immune Evasion Strategies Used by Zika Virus to Infect the Fetal Eye and Brain

(2019) Branden R. Nelson et al.   VIRAL IMMUNOLOGY

Single cell transcriptional signatures of the human placenta in term and preterm parturition

(2019) Roger Pique-Regi et al.   eLife

Timing of Gestational Exposure to Zika Virus is Associated with Postnatal Growth Restriction in a Murine Model

(2018) Gregory C. Valentine et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Extracellular vesicles generated by placental tissues ex vivo: A transport system for immune mediators and growth factors

(2018) Wendy Fitzgerald et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Viral Infections in Pregnancy: A Focus on Ebola Virus

(2018) Nicole S. Olgun   CURRENT PHARMACEUTICAL DESIGN

Miscarriage and stillbirth following maternal Zika virus infection in nonhuman primates

(2018) Dawn M. Dudley et al.   NATURE MEDICINE

Congenital Zika virus infection as a silent pathology with loss of neurogenic output in the fetal brain

(2018) Kristina M Adams Waldorf et al.   NATURE MEDICINE

Infection by Zika viruses requires the transmembrane protein AXL, endocytosis and low pH

(2018) Mirjana Persaud et al.   VIROLOGY

Wild-type human coronaviruses prefer cell-surface TMPRSS2 to endosomal cathepsins for cell entry

(2018) Kazuya Shirato et al.   VIROLOGY

Zika Virus and the Non-Microcephalic Fetus: Why We Should Still Worry

(2018) Christie L. Walker et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

An Unbiased Screen for Human Cytomegalovirus Identifies Neuropilin-2 as a Central Viral Receptor

(2018) Nadia Martinez-Martin et al.   CELL

Advantages of Single-Nucleus over Single-Cell RNA Sequencing of Adult Kidney: Rare Cell Types and Novel Cell States Revealed in Fibrosis

(2018) Haojia Wu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Single-cell reconstruction of the early maternal–fetal interface in humans

(2018) Roser Vento-Tormo et al.   NATURE

Dimensionality reduction for visualizing single-cell data using UMAP

(2018) Etienne Becht et al.   NATURE BIOTECHNOLOGY

Inhibition of autophagy limits vertical transmission of Zika virus in pregnant mice

(2017) Bin Cao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MERS-CoV Infection in a Pregnant Woman in Korea

(2017) Soo Young Jeong et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Massively parallel single-nucleus RNA-seq with DroNc-seq

(2017) Naomi Habib et al.   NATURE METHODS

Congenital cytomegalovirus infection undermines early development and functions of the human placenta

(2017) Lenore Pereira et al.   PLACENTA

AXL-dependent infection of human fetal endothelial cells distinguishes Zika virus from other pathogenic flaviviruses

(2017) Audrey Stéphanie Richard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrative single-cell and cell-free plasma RNA transcriptomics elucidates placental cellular dynamics

(2017) Jason C. H. Tsang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Primary Human Placental Trophoblasts are Permissive for Zika Virus (ZIKV) Replication

(2017) Kjersti M. Aagaard et al.   Scientific Reports

TAM Receptors Are Not Required for Zika Virus Infection in Mice

(2017) Andrew K. Hastings et al.   Cell Reports

HSV-2 enhances ZIKV infection of the placenta and induces apoptosis in first-trimester trophoblast cells

(2016) Paulomi Aldo et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Impact of Middle East Respiratory Syndrome coronavirus (MERS‐CoV) on pregnancy and perinatal outcome

(2016) Haleema Alserehi et al.   BMC INFECTIOUS DISEASES

Ebola Virus Disease in Pregnancy: Clinical, Histopathologic, and Immunohistochemical Findings

(2016) Atis Muehlenbachs et al.   JOURNAL OF INFECTIOUS DISEASES

Clinical Isolates of Human Coronavirus 229E Bypass the Endosome for Cell Entry

(2016) Kazuya Shirato et al.   JOURNAL OF VIROLOGY

Near-optimal probabilistic RNA-seq quantification

(2016) Nicolas L Bray et al.   NATURE BIOTECHNOLOGY

Fetal brain lesions after subcutaneous inoculation of Zika virus in a pregnant nonhuman primate

(2016) Kristina M Adams Waldorf et al.   NATURE MEDICINE

Zika virus — reigniting the TORCH

(2016) Carolyn B. Coyne et al.   NATURE REVIEWS MICROBIOLOGY

What is the placenta?

(2015) Graham J. Burton et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance

(2015) Chong Jai Kim et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Placenta: The Forgotten Organ

(2015) Emin Maltepe et al.   Annual Review of Cell and Developmental Biology

Isolation of Leukocytes from the Human Maternal-fetal Interface

(2015) Yi Xu et al.   Jove-Journal of Visualized Experiments

New Insights into the Relationship between Viral Infection and Pregnancy Complications

(2014) Ja-Young Kwon et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Influenza, Immune System, and Pregnancy

(2014) Renju S. Raj et al.   Reproductive Sciences

TMPRSS2 and ADAM17 Cleave ACE2 Differentially and Only Proteolysis by TMPRSS2 Augments Entry Driven by the Severe Acute Respiratory Syndrome Coronavirus Spike Protein

(2013) A. Heurich et al.   JOURNAL OF VIROLOGY

Review: Cell-free fetal DNA in the maternal circulation as an indication of placental health and disease

(2013) E.S. Taglauer et al.   PLACENTA

Gonadotropin-releasing hormone/gonadotropin-releasing hormone receptor signaling in the placenta

(2013) Kirsten Sasaki et al.   Current Opinion in Endocrinology Diabetes and Obesity

The influence of pregnancy on systemic immunity

(2012) Michael Pazos et al.   IMMUNOLOGIC RESEARCH

2009 pandemic influenza A (H1N1) in pregnancy: a systematic review of the literature

(2011) Laura G. Mosby et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Macrophages at the Fetal-Maternal Interface Express Markers of Alternative Activation and Are Induced by M-CSF and IL-10

(2011) J. Svensson et al.   JOURNAL OF IMMUNOLOGY

Pandemic influenza A (H1N1) in pregnant women: impact of early diagnosis and antiviral treatment

(2010) Minerva Cervantes-Gonzalez et al.   Expert Review of Anti-Infective Therapy

Pandemic 2009 Influenza A(H1N1) Virus Illness Among Pregnant Women in the United States

(2010) Alicia M. Siston   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Villitis of Unknown Etiology Is Associated with a Distinct Pattern of Chemokine Up-Regulation in the Feto-Maternal and Placental Compartments: Implications for Conjoint Maternal Allograft Rejection and Maternal Anti-Fetal Graft-versus-Host Disease

(2009) M. J. Kim et al.   JOURNAL OF IMMUNOLOGY

Whole-genome microarray and targeted analysis of angiogenesis-regulating gene expression (ENG, FLT1, VEGF, PlGF) in placentas from pre-eclamptic and small-for-gestational-age pregnancies

(2008) Johanne Holm Toft et al.   Journal of Maternal-Fetal & Neonatal Medicine