Resistance to Bacillus thuringiensis Cry1Ac toxin requires mutations in two Plutella xylostella ATP-binding cassette transporter paralogs

Functional redundancy of two ABC transporter proteins in mediating toxicity of Bacillus thuringiensis to cotton bollworm

(2020) Jing Wang et al.   PLoS Pathogens

CRISPR-Mediated Knockout of the ABCC2 Gene in Ostrinia furnacalis Confers High-Level Resistance to the Bacillus thuringiensis Cry1Fa Toxin

(2020) Xingliang Wang et al.   Toxins

Evaluation of five candidate receptors for three Bt toxins in the beet armyworm using CRISPR-mediated gene knockouts

(2020) Jianlei Huang et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

CRISPR/Cas9-mediated knockout of both the PxABCC2 and PxABCC3 genes confers high-level resistance to Bacillus thuringiensis Cry1Ac toxin in the diamondback moth, Plutella xylostella (L.)

(2019) Zhaojiang Guo et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Field-Evolved Resistance of Northern and Western Corn Rootworm (Coleoptera: Chrysomelidae) Populations to Corn Hybrids Expressing Single and Pyramided Cry3Bb1 and Cry34/35Ab1 Bt Proteins in North Dakota

(2019) Veronica Calles-Torrez et al.   JOURNAL OF ECONOMIC ENTOMOLOGY

Global Patterns of Resistance to Bt Crops Highlighting Pink Bollworm in the United States, China, and India

(2019) Bruce E Tabashnik et al.   JOURNAL OF ECONOMIC ENTOMOLOGY

A single amino acid polymorphism in ABCC2 loop 1 is responsible for differential toxicity of Bacillus thuringiensis Cry1Ac toxin in different Spodoptera (Noctuidae) species

(2018) Leilei Liu et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Extracellular loop structures in silkworm ABCC transporters determine their specificities forBacillus thuringiensisCry toxins

(2018) Haruka Endo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Bacillus thuringiensis Cry1A toxins domains in the binding to the ABCC2 receptor from Spodoptera exigua

(2018) María Martínez-Solís et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Bacillus thuringiensis Cry1A toxins exert toxicity by multiple pathways in insects

(2018) Shaohua Wang et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Expressing a moth abcc2 gene in transgenic Drosophila causes susceptibility to Bt Cry1Ac without requiring a cadherin-like protein receptor

(2017) Tristan Stevens et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

An Overview of Mechanisms of Cry Toxin Resistance in Lepidopteran Insects

(2017) B. Peterson et al.   JOURNAL OF ECONOMIC ENTOMOLOGY

Surge in insect resistance to transgenic crops and prospects for sustainability

(2017) Bruce E Tabashnik et al.   NATURE BIOTECHNOLOGY

Cry toxin specificities of insect ABCC transporters closely related to lepidopteran ABCC2 transporters

(2017) Haruka Endo et al.   PEPTIDES

ABCC2 is associated with Bacillus thuringiensis Cry1Ac toxin oligomerization and membrane insertion in diamondback moth

(2017) Josue Ocelotl et al.   Scientific Reports

Three toxins, two receptors, one mechanism: Mode of action of Cry1A toxins from Bacillus thuringiensis in Heliothis virescens

(2016) Anne Bretschneider et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

CRISPR/Cas9 mediated knockout of the abdominal-A homeotic gene in the global pest, diamondback moth (Plutella xylostella)

(2016) Yuping Huang et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Endogenous expression of a Bt toxin receptor in the Cry1Ac-susceptible insect cell line and its synergistic effect with cadherin on cytotoxicity of activated Cry1Ac

(2015) Zuwen Chen et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

A single type of cadherin is involved inBacillus thuringiensistoxicity inPlutella xylostella

(2015) Y. Park et al.   INSECT MOLECULAR BIOLOGY

The midgut cadherin-like gene is not associated with resistance to Bacillus thuringiensis toxin Cry1Ac in Plutella xylostella (L.)

(2015) Zhaojiang Guo et al.   JOURNAL OF INVERTEBRATE PATHOLOGY

MAPK Signaling Pathway Alters Expression of Midgut ALP and ABCC Genes and Causes Resistance to Bacillus thuringiensis Cry1Ac Toxin in Diamondback Moth

(2015) Zhaojiang Guo et al.   PLoS Genetics

ABCC transporters mediate insect resistance to multiple Bt toxins revealed by bulk segregant analysis

(2014) Youngjin Park et al.   BMC BIOLOGY

Mis-splicing of the ABCC2 gene linked with Bt toxin resistance in Helicoverpa armigera

(2014) Yutao Xiao et al.   Scientific Reports

Bacillus thuringiensis Toxins: An Overview of Their Biocidal Activity

(2014) Leopoldo Palma et al.   Toxins

The ATP-binding cassette transporter subfamily C member 2 inBombyx morilarvae is a functional receptor for Cry toxins fromBacillus thuringiensis

(2013) Shiho Tanaka et al.   FEBS Journal

Diamondback Moth Ecology and Management: Problems, Progress, and Prospects

(2012) Michael J. Furlong et al.   Annual Review of Entomology

Learning the ABCs of Bt: ABC transporters and insect resistance to Bacillus thuringiensis provide clues to a crucial step in toxin mode of action

(2012) David G. Heckel   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Diverse genetic basis of field-evolved resistance to Bt cotton in cotton bollworm from China

(2012) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single amino acid mutation in an ATP-binding cassette transporter gene causes resistance to Bt toxin Cry1Ab in the silkworm, Bombyx mori

(2012) S. Atsumi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parallel Evolution ofBacillus thuringiensisToxin Resistance in Lepidoptera

(2011) Simon W. Baxter et al.   GENETICS

An ABC Transporter Mutation Is Correlated with Insect Resistance to Bacillus thuringiensis Cry1Ac Toxin

(2010) Linda J. Gahan et al.   PLoS Genetics