HIV infects astrocytes in vivo and egresses from the brain to the periphery

Correction to: Astrocytes as an HIV CNS reservoir: highlights and reflections of an NIMH-sponsored symposium

(2019) Lena Al-Harthi et al.   JOURNAL OF NEUROVIROLOGY

Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice

(2019) Prasanta K. Dash et al.   Nature Communications

Letter to Editor

(2018) Lena Al-Harthi et al.   Journal of Neuroimmune Pharmacology

Defining total-body AIDS-virus burden with implications for curative strategies

(2017) Jacob D Estes et al.   NATURE MEDICINE

HIV persistence in tissue macrophages of humanized myeloid-only mice during antiretroviral therapy

(2017) Jenna B Honeycutt et al.   NATURE MEDICINE

Brain Macrophages in Simian Immunodeficiency Virus-Infected, Antiretroviral-Suppressed Macaques: a Functional Latent Reservoir

(2017) Claudia R. Avalos et al.   mBio

Astrocytes Resist HIV-1 Fusion but Engulf Infected Macrophage Material

(2017) Rebecca A. Russell et al.   Cell Reports

Ex vivo activation of CD4+ T-cells from donors on suppressive ART can lead to sustained production of infectious HIV-1 from a subset of infected cells

(2017) John K. Bui et al.   PLoS Pathogens

The search for true numbers of neurons and glial cells in the human brain: A review of 150 years of cell counting

(2016) Christopher S. von Bartheld et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Broad activation of latent HIV-1 in vivo

(2016) Kirston Barton et al.   Nature Communications

Targeting the Brain Reservoirs: Toward an HIV Cure

(2016) Céline Marban et al.   Frontiers in Immunology

HIV-infected microglia mediate cathepsin B-induced neurotoxicity

(2015) Frances Zenón et al.   JOURNAL OF NEUROVIROLOGY

Enigma of HIV-1 latent infection in astrocytes: an in-vitro study using protein kinase C agonist as a latency reversing agent

(2015) Ashok Chauhan   MICROBES AND INFECTION

Endocytosis of human immunodeficiency virus 1 (HIV-1) in astrocytes: A fiery path to its destination

(2015) Ashok Chauhan et al.   MICROBIAL PATHOGENESIS

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

Low levels of HIV-1 RNA detected in the cerebrospinal fluid after up to 10 years of suppressive therapy are associated with local immune activation

(2014) Viktor Dahl et al.   AIDS

A Competitive Advantage by Neonatally Engrafted Human Glial Progenitors Yields Mice Whose Brains Are Chimeric for Human Glia

(2014) M. S. Windrem et al.   JOURNAL OF NEUROSCIENCE

Cell–cell contact viral transfer contributes to HIV infection and persistence in astrocytes

(2014) Xiaoyu Luo et al.   JOURNAL OF NEUROVIROLOGY

Three-Dimensional Imaging of HIV-1 Virological Synapses Reveals Membrane Architectures Involved in Virus Transmission

(2014) T. Do et al.   JOURNAL OF VIROLOGY

Endocytosis-mediated HIV-1 entry and its significance in the elusive behavior of the virus in astrocytes

(2014) Ashok Chauhan et al.   VIROLOGY

Forebrain Engraftment by Human Glial Progenitor Cells Enhances Synaptic Plasticity and Learning in Adult Mice

(2013) Xiaoning Han et al.   Cell Stem Cell

Monocyte/macrophages and their role in HIV neuropathogenesis

(2013) Tricia H. Burdo et al.   IMMUNOLOGICAL REVIEWS

Epigenetic Regulation of HIV-1 Latency in Astrocytes

(2013) S. D. Narasipura et al.   JOURNAL OF VIROLOGY

HIV-1-Related Central Nervous System Disease: Current Issues in Pathogenesis, Diagnosis, and Treatment

(2013) S. Spudich et al.   Cold Spring Harbor Perspectives in Medicine

Cerebrospinal fluid HIV escape associated with progressive neurologic dysfunction in patients on antiretroviral therapy with well controlled plasma viral load

(2012) Michael J. Peluso et al.   AIDS

Central Nervous System Viral Invasion and Inflammation During Acute HIV Infection

(2012) Victor Valcour et al.   JOURNAL OF INFECTIOUS DISEASES

Human Immunodeficiency Virus Type 1 (HIV-1) Transactivator of Transcription through Its Intact Core and Cysteine-Rich Domains Inhibits Wnt/ -Catenin Signaling in Astrocytes: Relevance to HIV Neuropathogenesis

(2012) L. J. Henderson et al.   JOURNAL OF NEUROSCIENCE

Identification of Novel T Cell Factor 4 (TCF-4) Binding Sites on the HIV Long Terminal Repeat Which Associate with TCF-4,  -Catenin, and SMAR1 To Repress HIV Transcription

(2012) L. J. Henderson et al.   JOURNAL OF VIROLOGY

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

(2012) N. M. Archin et al.   NATURE

Glial Progenitor Cell-Based Treatment and Modeling of Neurological Disease

(2012) S. A. Goldman et al.   SCIENCE

Role of  -Catenin and TCF/LEF Family Members in Transcriptional Activity of HIV in Astrocytes

(2011) S. D. Narasipura et al.   JOURNAL OF VIROLOGY

HIV-1 Replication in the Central Nervous System Occurs in Two Distinct Cell Types

(2011) Gretja Schnell et al.   PLoS Pathogens

Estimating time since infection in early homogeneous HIV-1 samples using a poisson model

(2010) Elena E Giorgi et al.   BMC BIOINFORMATICS

Extensive astrocyte infection is prominent in human immunodeficiency virus-associated dementia

(2009) Melissa J. Churchill et al.   ANNALS OF NEUROLOGY

A highly sensitive and dynamic immunofluorescent cytometric bead assay for the detection of HIV-1 p24

(2009) Angélique Biancotto et al.   JOURNAL OF VIROLOGICAL METHODS

Compartmentalization and Clonal Amplification of HIV-1 Variants in the Cerebrospinal Fluid during Primary Infection

(2009) G. Schnell et al.   JOURNAL OF VIROLOGY

A Simian Immunodeficiency Virus-Infected Macaque Model To Study Viral Reservoirs That Persist during Highly Active Antiretroviral Therapy

(2009) J. B. Dinoso et al.   JOURNAL OF VIROLOGY

Detecting HIV-1 integration by repetitive-sampling Alu-gag PCR

(2009) Megan K. Liszewski et al.   METHODS

HIV Evolution in Early Infection: Selection Pressures, Patterns of Insertion and Deletion, and the Impact of APOBEC

(2009) Natasha Wood et al.   PLoS Pathogens

Validation of the CNS Penetration-Effectiveness Rank for Quantifying Antiretroviral Penetration Into the Central Nervous System

(2008) Scott Letendre   ARCHIVES OF NEUROLOGY

Neonatal Chimerization with Human Glial Progenitor Cells Can Both Remyelinate and Rescue the Otherwise Lethally Hypomyelinated Shiverer Mouse

(2008) Martha S. Windrem et al.   Cell Stem Cell

Deciphering Human Immunodeficiency Virus Type 1 Transmission and Early Envelope Diversification by Single-Genome Amplification and Sequencing

(2008) J. F. Salazar-Gonzalez et al.   JOURNAL OF VIROLOGY

Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

(2008) B. F. Keele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chloroquine mediated molecular tuning of astrocytes for enhanced permissiveness to HIV infection

(2008) Theophilus S. Vijaykumar et al.   VIROLOGY