Transcriptomic stratification of late-onset Alzheimer's cases reveals novel genetic modifiers of disease pathology

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk

(2019) Iris E. Jansen et al.   NATURE GENETICS

The neuropathological diagnosis of Alzheimer’s disease

(2019) Michael A. DeTure et al.   Molecular Neurodegeneration

Understanding Alzheimer Disease at the Interface between Genetics and Transcriptomics

(2018) Jan Verheijen et al.   TRENDS IN GENETICS

Item-level analyses reveal genetic heterogeneity in neuroticism

(2018) Mats Nagel et al.   Nature Communications

Brain Cell Type Specific Gene Expression and Co-expression Network Architectures

(2018) Andrew T. McKenzie et al.   Scientific Reports

The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease

(2018) Minghui Wang et al.   Scientific Data

A multi-omic atlas of the human frontal cortex for aging and Alzheimer’s disease research

(2018) Philip L. De Jager et al.   Scientific Data

Leveraging Polygenic Functional Enrichment to Improve GWAS Power

(2018) Gleb Kichaev et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019

(2018) Annalisa Buniello et al.   NUCLEIC ACIDS RESEARCH

Targeting psychologic stress signaling pathways in Alzheimer’s disease

(2017) Hunter S. Futch et al.   Molecular Neurodegeneration

Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies

(2017) L B Chibnik et al.   MOLECULAR PSYCHIATRY

Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice

(2017) Zoe A. Klein et al.   NEURON

Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data

(2017) Charles C. White et al.   PLOS MEDICINE

Distinct subtypes of Alzheimer’s disease based on patterns of brain atrophy: longitudinal trajectories and clinical applications

(2017) Daniel Ferreira et al.   Scientific Reports

Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease

(2016) Jonathan M. Schott et al.   Alzheimers & Dementia

The Cellular Phase of Alzheimer’s Disease

(2016) Bart De Strooper et al.   CELL

Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseases

(2016) Mariet Allen et al.   Scientific Data

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

NbClust: AnRPackage for Determining the Relevant Number of Clusters in a Data Set

(2015) Malika Charrad et al.   Journal of Statistical Software

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Pro-Inflammatory S100A8 and S100A9 Proteins: Self-Assembly into Multifunctional Native and Amyloid Complexes

(2012) Thomas Vogl et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years

(2011) Heiko Braak et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Comparison of Clustering Methods for Investigation of Genome-Wide Methylation Array Data

(2011) Harry Clifford et al.   Frontiers in Genetics

Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease

(2010) S J Furney et al.   MOLECULAR PSYCHIATRY

Variance component model to account for sample structure in genome-wide association studies

(2010) Hyun Min Kang et al.   NATURE GENETICS

Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses

(2008) Lars Bertram et al.   NATURE REVIEWS NEUROSCIENCE