Spontaneous mutations that confer resistance to 2-deoxyglucose act through Hxk2 and Snf1 pathways to regulate gene expression and HXT endocytosis

Activation and inhibition of Snf1 kinase activity by phosphorylation within the activation loop

(2016) Rhonda R. McCartney et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The β subunit of yeast AMP-activated protein kinase directs substrate specificity in response to alkaline stress

(2016) Dakshayini G. Chandrashekarappa et al.   CELLULAR SIGNALLING

Near-optimal probabilistic RNA-seq quantification

(2016) Nicolas L Bray et al.   NATURE BIOTECHNOLOGY

Metabolic Enzymes Moonlighting in the Nucleus: Metabolic Regulation of Gene Transcription

(2016) Aristeidis E. Boukouris et al.   TRENDS IN BIOCHEMICAL SCIENCES

Proteasomes, Sir2, and Hxk2 Form an Interconnected Aging Network That Impinges on the AMPK/Snf1-Regulated Transcriptional Repressor Mig1

(2015) Yanhua Yao et al.   PLoS Genetics

Inexpensive Multiplexed Library Preparation for Megabase-Sized Genomes

(2015) Michael Baym et al.   PLoS One

A Comparison of Methods to Measure Fitness in Escherichia coli

(2015) Michael J. Wiser et al.   PLoS One

Energy restriction mimetic agents to target cancer cells: Comparison between 2-deoxyglucose and thiazolidinediones

(2014) Sandra Kuntz et al.   BIOCHEMICAL PHARMACOLOGY

Genetic Analysis of Resistance and Sensitivity to 2-Deoxyglucose in Saccharomyces cerevisiae

(2014) R. R. McCartney et al.   GENETICS

2-Deoxyglucose Impairs Saccharomyces cerevisiae Growth by Stimulating Snf1-Regulated and α-Arrestin-Mediated Trafficking of Hexose Transporters 1 and 3

(2014) Allyson F. O'Donnell et al.   MOLECULAR AND CELLULAR BIOLOGY

AMPK-Dependent Degradation of TXNIP upon Energy Stress Leads to Enhanced Glucose Uptake via GLUT1

(2013) Ning Wu et al.   MOLECULAR CELL

Lack ofHXK2Induces Localization of Active Ras in Mitochondria and Triggers Apoptosis in the YeastSaccharomyces cerevisiae

(2013) Loredana Amigoni et al.   Oxidative Medicine and Cellular Longevity

Phosphorylation of Yeast Hexokinase 2 Regulates Its Nucleocytoplasmic Shuttling

(2012) Paula Fernández-García et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

(2011) Sophia Y. Lunt et al.   Annual Review of Cell and Developmental Biology

Protein Kinase A Contributes to the Negative Control of Snf1 Protein Kinase in Saccharomyces cerevisiae

(2011) LaKisha Barrett et al.   EUKARYOTIC CELL

Reg1 Protein Regulates Phosphorylation of All Three Snf1 Isoforms but Preferentially Associates with the Gal83 Isoform

(2011) Yuxun Zhang et al.   EUKARYOTIC CELL

Functional domains of yeast hexokinase 2

(2010) Rafael Peláez et al.   BIOCHEMICAL JOURNAL

PP1 phosphatase-binding motif in Reg1 protein of Saccharomyces cerevisiae is required for interaction with both the PP1 phosphatase Glc7 and the Snf1 protein kinase

(2010) Shadi Tabba et al.   CELLULAR SIGNALLING

Discovery of Mutations in Saccharomyces cerevisiae by Pooled Linkage Analysis and Whole-Genome Sequencing

(2010) S. R. Birkeland et al.   GENETICS

Targeting tumor metabolism with 2-deoxyglucose in patients with castrate-resistant prostate cancer and advanced malignancies

(2010) Mark Stein et al.   PROSTATE

A catabolic block does not sufficiently explain how 2-deoxy-D-glucose inhibits cell growth

(2008) M. Ralser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA