The E3 Ubiquitin Ligase c-Cbl Inhibits Microglia-Mediated CNS Inflammation by Regulating PI3K/Akt/NF-κB Pathway

miR-216a rescues dexamethasone suppression of osteogenesis, promotes osteoblast differentiation and enhances bone formation, by regulating c-Cbl-mediated PI3K/AKT pathway

(2015) H Li et al.   CELL DEATH AND DIFFERENTIATION

Nrf2-ARE signals mediated the anti-oxidative action of electroacupuncture in an MPTP mouse model of Parkinson's disease

(2015) E. Lv et al.   FREE RADICAL RESEARCH

Systemic inflammation and microglial activation: systematic review of animal experiments

(2015) Inge C.M. Hoogland et al.   Journal of Neuroinflammation

Microglia-Mediated Inflammation and Neurodegenerative Disease

(2015) Ling Xu et al.   MOLECULAR NEUROBIOLOGY

The role of TLR4-mediated PTEN/PI3K/AKT/NF-κB signaling pathway in neuroinflammation in hippocampal neurons

(2014) M. Zhao et al.   NEUROSCIENCE

Isobutyrylshikonin inhibits lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in BV2 microglial cells by suppressing the PI3K/Akt-mediated nuclear transcription factor-κB pathway

(2014) Rajapaksha Gedara Prasad Tharanga Jayasooriya et al.   NUTRITION RESEARCH

MiR-9 promotes microglial activation by targeting MCPIP1

(2014) Honghong Yao et al.   Nature Communications

T Cell Activation Threshold Regulated by E3 Ubiquitin Ligase Cbl-b Determines Fate of Inducible Regulatory T Cells

(2013) G. Qiao et al.   JOURNAL OF IMMUNOLOGY

c-Cbl-Mediated Neddylation Antagonizes Ubiquitination and Degradation of the TGF-β Type II Receptor

(2013) Wei Zuo et al.   MOLECULAR CELL

Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation

(2013) Yichuan Xiao et al.   NATURE MEDICINE

The Role of the E3 Ligase Cbl-B in Murine Dendritic Cells

(2013) Stephanie Wallner et al.   PLoS One

Protein tyrosine kinase regulation by ubiquitination: Critical roles of Cbl-family ubiquitin ligases

(2012) Bhopal Mohapatra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Microglia and neurodegeneration: The role of systemic inflammation

(2012) Colm Cunningham   GLIA

Microglia in early disease stages

(2012) Katie Kingwell   Nature Reviews Neurology

The E3 ligase c-Cbl regulates dendritic cell activation

(2011) Shin-Heng Chiou et al.   EMBO REPORTS

Inflammation in neurodegenerative diseases

(2010) Sandra Amor et al.   IMMUNOLOGY

Microglia in neurodegenerative disease

(2010) V. Hugh Perry et al.   Nature Reviews Neurology

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Triptolide inhibits COX-2 expression and PGE2release by suppressing the activity of NF-κB and JNK in LPS-treated microglia

(2008) Yuntao Gong et al.   JOURNAL OF NEUROCHEMISTRY