Assessment of Luminal and Basal Phenotypes in Bladder Cancer

The Cancer Genome Atlas Expression Subtypes Stratify Response to Checkpoint Inhibition in Advanced Urothelial Cancer and Identify a Subset of Patients with High Survival Probability

(2019) Jaegil Kim et al.   EUROPEAN UROLOGY

Bladder Cancer in the Genomic Era

(2019) Charles C. Guo et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Dysregulation of EMT Drives the Progression to Clinically Aggressive Sarcomatoid Bladder Cancer

(2019) Charles C. Guo et al.   Cell Reports

Molecular Subtype-Specific Immunocompetent Models of High-Grade Urothelial Carcinoma Reveal Differential Neoantigen Expression and Response to Immunotherapy

(2018) Ryoichi Saito et al.   CANCER RESEARCH

The New Age of -omics in Urothelial Cancer – Re-wording Its Diagnosis and Treatment

(2018) Theodora Katsila et al.   EBioMedicine

Intratumoral Heterogeneity of Bladder Cancer by Molecular Subtypes and Histologic Variants

(2018) Joshua I. Warrick et al.   EUROPEAN UROLOGY

Impact of Molecular Subtypes in Muscle-invasive Bladder Cancer on Predicting Response and Survival after Neoadjuvant Chemotherapy

(2017) Roland Seiler et al.   EUROPEAN UROLOGY

Genetic Alterations in the Molecular Subtypes of Bladder Cancer: Illustration in the Cancer Genome Atlas Dataset

(2017) Woonyoung Choi et al.   EUROPEAN UROLOGY

Molecular classification of urothelial carcinoma: global mRNA classification versus tumour-cell phenotype classification

(2017) Gottfrid Sjödahl et al.   JOURNAL OF PATHOLOGY

Precision medicine for urothelial bladder cancer: update on tumour genomics and immunotherapy

(2017) Kenneth M. Felsenstein et al.   Nature Reviews Urology

Model selection in multivariate semiparametric regression

(2017) Zhuokai Li et al.   STATISTICAL METHODS IN MEDICAL RESEARCH

Intermediate and advanced topics in multilevel logistic regression analysis

(2017) Peter C. Austin et al.   STATISTICS IN MEDICINE

Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of bladder carcinoma

(2017) Ashish M. Kamat et al.   Journal for ImmunoTherapy of Cancer

Origins of Bladder Cancer

(2016) Bogdan Czerniak et al.   Annual Review of Pathology-Mechanisms of Disease

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

(2016) Zuguang Gu et al.   BIOINFORMATICS

Gene Expression Profile of the Clinically Aggressive Micropapillary Variant of Bladder Cancer

(2016) Charles Chuanhai Guo et al.   EUROPEAN UROLOGY

ERBB2 Mutations Characterize a Subgroup of Muscle-invasive Bladder Cancers with Excellent Response to Neoadjuvant Chemotherapy

(2016) Floris H. Groenendijk et al.   EUROPEAN UROLOGY

A Prognostic Gene Expression Signature in the Molecular Classification of Chemotherapy-naïve Urothelial Cancer is Predictive of Clinical Outcomes from Neoadjuvant Chemotherapy: A Phase 2 Trial of Dose-dense Methotrexate, Vinblastine, Doxorubicin, and Cisplatin with Bevacizumab in Urothelial Cancer

(2016) David J. McConkey et al.   EUROPEAN UROLOGY

Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells

(2016) Marco De Simone et al.   IMMUNITY

Bladder cancer

(2016) Ashish M Kamat et al.   LANCET

Meta-Analysis of the Luminal and Basal Subtypes of Bladder Cancer and the Identification of Signature Immunohistochemical Markers for Clinical Use

(2016) Vipulkumar Dadhania et al.   EBioMedicine

Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential

(2015) Padmanee Sharma et al.   CELL

A Universal Approximate Cross-Validation Criterion for Regular Risk Functions

(2015) Daniel Commenges et al.  

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

A Universal Approximate Cross-Validation Criterion for Regular Risk Functions

(2015) Daniel Commenges et al.   International Journal of Biostatistics

Identification of Distinct Basal and Luminal Subtypes of Muscle-Invasive Bladder Cancer with Different Sensitivities to Frontline Chemotherapy

(2014) Woonyoung Choi et al.   CANCER CELL

Prognostic B-cell Signatures Using mRNA-Seq in Patients with Subtype-Specific Breast and Ovarian Cancer

(2014) M. D. Iglesia et al.   CLINICAL CANCER RESEARCH

Comprehensive molecular characterization of urothelial bladder carcinoma

(2014)   NATURE

Bladder cancers arise from distinct urothelial sub-populations

(2014) Jason Van Batavia et al.   NATURE CELL BIOLOGY

Cellular origin of bladder neoplasia and tissue dynamics of its progression to invasive carcinoma

(2014) Kunyoo Shin et al.   NATURE CELL BIOLOGY

Intrinsic basal and luminal subtypes of muscle-invasive bladder cancer

(2014) Woonyoung Choi et al.   Nature Reviews Urology

Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology

(2014) J. S. Damrauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Somatic ERCC2 Mutations Correlate with Cisplatin Sensitivity in Muscle-Invasive Urothelial Carcinoma

(2014) E. M. Van Allen et al.   Cancer Discovery

Toward a Molecular Pathologic Classification of Urothelial Carcinoma

(2013) Gottfrid Sjödahl et al.   AMERICAN JOURNAL OF PATHOLOGY

Fibroblast Growth Factor Receptors-1 and -3 Play Distinct Roles in the Regulation of Bladder Cancer Growth and Metastasis: Implications for Therapeutic Targeting

(2013) Tiewei Cheng et al.   PLoS One

An Epithelial-Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

(2012) L. A. Byers et al.   CLINICAL CANCER RESEARCH

A Molecular Taxonomy for Urothelial Carcinoma

(2012) G. Sjodahl et al.   CLINICAL CANCER RESEARCH

pROC: an open-source package for R and S+ to analyze and compare ROC curves

(2011) Xavier Robin et al.   BMC BIOINFORMATICS

Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder

(2011) Yaoting Gui et al.   NATURE GENETICS

Combined Gene Expression and Genomic Profiling Define Two Intrinsic Molecular Subtypes of Urothelial Carcinoma and Gene Signatures for Molecular Grading and Outcome

(2010) David Lindgren et al.   CANCER RESEARCH

Gene Expression Profiles Identify Inflammatory Signatures in Dendritic Cells

(2010) Anna Torri et al.   PLoS One

Inactivation of p53 and Pten promotes invasive bladder cancer

(2009) A. M. Puzio-Kuter et al.   GENES & DEVELOPMENT