Neuroprotective Efficacy of an Aminopropyl Carbazole Derivative P7C3-A20 in Ischemic Stroke

Differential modulation of GABAA and NMDA receptors by α7-nicotinic receptor desensitization in cultured rat hippocampal neurons

(2016) Lei Shen et al.   ACTA PHARMACOLOGICA SINICA

DT270-326, a Truncated Diphtheria Toxin, Increases Blood-Tumor Barrier Permeability by Upregulating the Expression of Caveolin-1

(2016) Yang Lin et al.   CNS Neuroscience & Therapeutics

Targeting Nicotinamide Phosphoribosyltransferase as a Potential Therapeutic Strategy to Restore Adult Neurogenesis

(2016) Shu-Na Wang et al.   CNS Neuroscience & Therapeutics

DCLAK11, a multi-tyrosine kinase inhibitor, exhibits potent antitumor and antiangiogenic activity in vitro

(2015) Xiao-bin Guo et al.   ACTA PHARMACOLOGICA SINICA

DanHong injection dose-dependently varies amino acid metabolites and metabolic pathways in the treatment of rats with cerebral ischemia

(2015) Zhi-li Guo et al.   ACTA PHARMACOLOGICA SINICA

Chronic nicotine treatment enhances vascular smooth muscle relaxation in rats

(2015) Tian-ying Xu et al.   ACTA PHARMACOLOGICA SINICA

TLR3 ligand Poly IC Attenuates Reactive Astrogliosis and Improves Recovery of Rats after Focal Cerebral Ischemia

(2015) Yang Li et al.   CNS Neuroscience & Therapeutics

Neuroprotective Effects of Direct Intrathecal Administration of Granulocyte Colony-Stimulating Factor in Rats with Spinal Cord Injury

(2015) Wu-Fu Chen et al.   CNS Neuroscience & Therapeutics

Dual Antiplatelet Therapy of Clopidogrel and Aspirin in Secondary Prevention of Ischemic Stroke: Evidence and Indications

(2015) Ya Su et al.   CNS Neuroscience & Therapeutics

Nicotinamide Phosphoribosyltransferase Facilitates Post-Stroke Angiogenesis

(2015) Pei Wang et al.   CNS Neuroscience & Therapeutics

Perspective for Stroke and Brain Injury Research: Mechanisms and Potential Therapeutic Targets

(2015) Jun Chen et al.   CNS Neuroscience & Therapeutics

Remote Ischemic Preconditioning-Mediated Neuroprotection against Stroke is Associated with Significant Alterations in Peripheral Immune Responses

(2015) Zong-Jian Liu et al.   CNS Neuroscience & Therapeutics

Pharmacologic rescue of motor and sensory function by the neuroprotective compound P7C3 following neonatal nerve injury

(2015) S.W.P. Kemp et al.   NEUROSCIENCE

Chronic P7C3 treatment restores hippocampal neurogenesis

(2015) Sarah E. Latchney et al.   NEUROSCIENCE LETTERS

Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) as a therapeutic strategy in cancer

(2015) Deepak Sampath et al.   PHARMACOLOGY & THERAPEUTICS

Regenerative Neurogenesis After Ischemic Stroke Promoted by Nicotinamide Phosphoribosyltransferase–Nicotinamide Adenine Dinucleotide Cascade

(2015) Yan Zhao et al.   STROKE

NAMPT as a Therapeutic Target against Stroke

(2015) Pei Wang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Discovery of Novel Inhibitors and Fluorescent Probe Targeting NAMPT

(2015) Xia Wang et al.   Scientific Reports

Discovery and characterization of novel small-molecule inhibitors targeting nicotinamide phosphoribosyltransferase

(2015) Tian-Ying Xu et al.   Scientific Reports

Sevoflurane post-conditioning protects isolated rat hearts against ischemia-reperfusion injury via activation of the ERK1/2 pathway

(2014) Hong Xie et al.   ACTA PHARMACOLOGICA SINICA

ARRB1/β-arrestin-1 mediates neuroprotection through coordination of BECN1-dependent autophagy in cerebral ischemia

(2014) Pei Wang et al.   Autophagy

Intracellular NAMPT–NAD+–SIRT1 cascade improves post-ischaemic vascular repair by modulating Notch signalling in endothelial progenitors

(2014) Pei Wang et al.   CARDIOVASCULAR RESEARCH

P7C3 Neuroprotective Chemicals Function by Activating the Rate-Limiting Enzyme in NAD Salvage

(2014) Gelin Wang et al.   CELL

Extracellular Visfatin has Nicotinamide Phosphoribosyltransferase Enzymatic Activity and is Neuroprotective Against Ischemic Injury

(2014) Yan Zhao et al.   CNS Neuroscience & Therapeutics

Anti-tissue Plasminogen Activator (tPA) as an Effective Therapy of Neonatal Hypoxia-Ischemia with and without Inflammation

(2014) Dianer Yang et al.   CNS Neuroscience & Therapeutics

Early Detection of Subclinical Visual Damage After Blast-Mediated TBI Enables Prevention of Chronic Visual Deficit by Treatment With P7C3-S243

(2014) L. M. Dutca et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Discovery of a Neuroprotective Chemical, (S)-N-(3-(3,6-Dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine [(−)-P7C3-S243], with Improved Druglike Properties

(2014) Jacinth Naidoo et al.   JOURNAL OF MEDICINAL CHEMISTRY

The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis

(2014) A K Walker et al.   MOLECULAR PSYCHIATRY

Found in Translation

(2014) Ulrich Dirnagl et al.   STROKE

P7C3 Neuroprotective Chemicals Block Axonal Degeneration and Preserve Function after Traumatic Brain Injury

(2014) Terry C. Yin et al.   Cell Reports

Nucleolin protects the heart from ischaemia–reperfusion injury by up-regulating heat shock protein 32

(2013) Bimei Jiang et al.   CARDIOVASCULAR RESEARCH

Neuroprotective Efficacy of a Proneurogenic Compound after Traumatic Brain Injury

(2013) Meghan O. Blaya et al.   JOURNAL OF NEUROTRAUMA

Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia

(2012) Pei Wang et al.   Autophagy

Loss of AMP-Activated Protein Kinase-α2 Impairs the Insulin-Sensitizing Effect of Calorie Restriction in Skeletal Muscle

(2012) Pei Wang et al.   DIABETES

Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis

(2012) R. Tesla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease

(2012) H. De Jesus-Cortes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A fluorometric assay for high-throughput screening targeting nicotinamide phosphoribosyltransferase

(2011) Ruo-Yu Zhang et al.   ANALYTICAL BIOCHEMISTRY

Nicotinamide phosphoribosyltransferase protects against ischemic stroke through SIRT1-dependent adenosine monophosphate-activated kinase pathway

(2011) Pei Wang et al.   ANNALS OF NEUROLOGY

Increased Oxidative Stress Is Responsible for Severer Cerebral Infarction in Stroke-Prone Spontaneously Hypertensive Rats

(2011) Xiu-Hua Zhang et al.   CNS Neuroscience & Therapeutics

Visfatin and Cardio–Cerebro–Vascular Disease

(2011) Pei Wang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Stroke rehabilitation

(2011) Peter Langhorne et al.   LANCET

Discovery of a Proneurogenic, Neuroprotective Chemical

(2010) Andrew A. Pieper et al.   CELL

PARP-1 is involved in autophagy induced by DNA damage

(2009) José Antonio Muñoz-Gámez et al.   Autophagy

Perivascular adipose tissue-derived visfatin is a vascular smooth muscle cell growth factor: role of nicotinamide mononucleotide

(2008) Pei Wang et al.   CARDIOVASCULAR RESEARCH