Artesunate Ameliorates Experimental Autoimmune Encephalomyelitis by Inhibiting Leukocyte Migration to the Central Nervous System

Immune cell trafficking across the barriers of the central nervous system in multiple sclerosis and stroke

(2016) Melissa A. Lopes Pinheiro et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Fingolimod: a review of its mode of action in the context of its efficacy and safety profile in relapsing forms of multiple sclerosis

(2016) Douglas R Jeffery et al.   Expert Review of Neurotherapeutics

Fingolimod ameliorates the development of experimental autoimmune encephalomyelitis by inhibiting Akt–mTOR axis in mice

(2016) Huiqing Hou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Different Effects of Tacrolimus on Innate and Adaptive Immune Cells in the Allograft Transplantation

(2016) K. Shao et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Fingolimod: a review of its mode of action in the context of its efficacy and safety profile in relapsing forms of multiple sclerosis

(2016) Douglas R Jeffery et al.   Expert Review of Neurotherapeutics

Dysregulation of sphingosine 1 phosphate receptor-1 (S1P1) signaling and regulatory lymphocyte-dependent immunosuppression in a model of post-fingolimod MS rebound

(2015) Leonardo Cavone et al.   BRAIN BEHAVIOR AND IMMUNITY

Neutralizing IL-17 protects the optic nerve from autoimmune pathology and prevents retinal nerve fiber layer atrophy during experimental autoimmune encephalomyelitis

(2015) Benjamin Knier et al.   JOURNAL OF AUTOIMMUNITY

IL-17–Producing Vγ4+γδ T Cells Require Sphingosine 1-Phosphate Receptor 1 for Their Egress from the Lymph Nodes under Homeostatic and Inflammatory Conditions

(2015) Yasuhiro Maeda et al.   JOURNAL OF IMMUNOLOGY

GM-CSF production by CD4+ T cells in MS patients: Regulation by regulatory T cells and vitamin D

(2015) E. Peelen et al.   JOURNAL OF NEUROIMMUNOLOGY

Role of the innate and adaptive immune responses in the course of multiple sclerosis

(2015) Bernhard Hemmer et al.   LANCET NEUROLOGY

Fingolimod does not impair T-cell release from the thymus and beneficially affects Treg function in patients with multiple sclerosis

(2015) Jürgen Haas et al.   Multiple Sclerosis Journal

Fingolimod does not impair T-cell release from the thymus and beneficially affects Treg function in patients with multiple sclerosis

(2015) Jürgen Haas et al.   Multiple Sclerosis Journal

Violacein Treatment Modulates Acute and Chronic Inflammation through the Suppression of Cytokine Production and Induction of Regulatory T Cells

(2015) Liana Verinaud et al.   PLoS One

Immunology of Relapse and Remission in Multiple Sclerosis

(2014) Lawrence Steinman   Annual Review of Immunology

Primaquine Treatment Suppresses Experimental Autoimmune Encephalomyelitis Severity

(2014) Fábio Zanucoli et al.   CNS Neuroscience & Therapeutics

Dendritic cells treated with crudePlasmodium bergheiextracts acquire immune-modulatory properties and suppress the development of autoimmune neuroinflammation

(2014) Rodolfo Thomé et al.   IMMUNOLOGY

Artesunate Ameliorates Functional Limitations in Freund’s Complete Adjuvant-Induced Monoarthritis in Rat by Maintaining Oxidative Homeostasis and Inhibiting COX-2 Expression

(2014) B. Guruprasad et al.   INFLAMMATION

Pathogenesis of multiple sclerosis: insights from molecular and metabolic imaging

(2014) Olga Ciccarelli et al.   LANCET NEUROLOGY

Artesunate Abolishes Germinal Center B Cells and Inhibits Autoimmune Arthritis

(2014) Lifei Hou et al.   PLoS One

Exacerbation of Autoimmune Neuro-Inflammation in Mice Cured from Blood-Stage Plasmodium berghei Infection

(2014) Rodolfo Thomé et al.   PLoS One

Rebound of disease activity during pregnancy after withdrawal of fingolimod

(2013) A. P. Sempere et al.   EUROPEAN JOURNAL OF NEUROLOGY

Dendritic cells treated with chloroquine modulate experimental autoimmune encephalomyelitis

(2013) Rodolfo Thomé et al.   IMMUNOLOGY AND CELL BIOLOGY

Chloroquine: Modes of action of an undervalued drug

(2013) Rodolfo Thomé et al.   IMMUNOLOGY LETTERS

Independent and Interdependent Immunoregulatory Effects of IL-27, IFN- , and IL-10 in the Suppression of Human Th17 Cells and Murine Experimental Autoimmune Encephalomyelitis

(2013) D. C. Fitzgerald et al.   JOURNAL OF IMMUNOLOGY

The potential role of T cell migration and chemotaxis as targets of glucocorticoids in multiple sclerosis and experimental autoimmune encephalomyelitis

(2013) Henrike J. Fischer et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Chloroquine Treatment Enhances Regulatory T Cells and Reduces the Severity of Experimental Autoimmune Encephalomyelitis

(2013) Rodolfo Thomé et al.   PLoS One

Rebound of Disease Activity After Withdrawal of Fingolimod (FTY720) Treatment

(2012) Joachim B. Havla   ARCHIVES OF NEUROLOGY

Oral tolerance and OVA-induced tolerogenic dendritic cells reduce the severity of collagen/ovalbumin-induced arthritis in mice

(2012) Rodolfo Thomé et al.   CELLULAR IMMUNOLOGY

Immunomodulatory and Anti-inflammatory Properties of Artesunate in Experimental Colitis

(2012) Z. Yang et al.   CURRENT MEDICINAL CHEMISTRY

Dihydroartemisinin Ameliorates Inflammatory Disease by Its Reciprocal Effects on Th and Regulatory T Cell Function via Modulating the Mammalian Target of Rapamycin Pathway

(2012) Yan G. Zhao et al.   JOURNAL OF IMMUNOLOGY

Inhibitory effect of the antimalarial agent artesunate on collagen-induced arthritis in rats through nuclear factor kappa B and mitogen-activated protein kinase signaling pathway

(2012) Yanmei Li et al.   Translational Research

Th17 lymphocytes traffic to the central nervous system independently of α4 integrin expression during EAE

(2011) Veit Rothhammer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF

(2011) Mohamed El-Behi et al.   NATURE IMMUNOLOGY

A Pilot Study of the Therapeutic Efficacy and Mechanism of Artesunate in the MRL/lpr Murine Model of Systemic Lupus Erythematosus

(2010) Ouyang Jin et al.   Cellular & Molecular Immunology

The anti-malaria agent artesunate inhibits expression of vascular endothelial growth factor and hypoxia-inducible factor-1α in human rheumatoid arthritis fibroblast-like synoviocyte

(2009) Ya He et al.   RHEUMATOLOGY INTERNATIONAL

Distinct Functions of Autoreactive Memory and Effector CD4+ T Cells in Experimental Autoimmune Encephalomyelitis

(2008) Wassim Elyaman et al.   AMERICAN JOURNAL OF PATHOLOGY