POE Immunoassay: Plate-based oligonucleotide electro-chemiluminescent immunoassay for the quantification of nucleic acids in biological matrices

Quantification of siRNA-Antibody Conjugates in Biological Matrices by Triplex-Forming Oligonucleotide ELISA

(2019) Sara C. Humphreys et al.   Nucleic Acid Therapeutics

Evaluation of GalNAc-siRNA Conjugate Activity in Pre-clinical Animal Models with Reduced Asialoglycoprotein Receptor Expression

(2018) Jennifer L.S. Willoughby et al.   MOLECULAR THERAPY

Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis

(2018) David Adams et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evaluation of size-exclusion chromatography for the analysis of phosphorothioate oligonucleotides

(2017) Atsuko Shimoyama et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

FDA-Approved Oligonucleotide Therapies in 2017

(2017) Cy A. Stein et al.   MOLECULAR THERAPY

Impact of enhanced metabolic stability on pharmacokinetics and pharmacodynamics of GalNAc–siRNA conjugates

(2017) Jayaprakash K. Nair et al.   NUCLEIC ACIDS RESEARCH

Therapeutic nucleic acids: current clinical status

(2016) Kannan Sridharan et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Development of antibody-siRNA conjugate targeted to cardiac and skeletal muscles

(2016) Tsukasa Sugo et al.   JOURNAL OF CONTROLLED RELEASE

Pharmacokinetics, biodistribution and cell uptake of antisense oligonucleotides

(2015) Richard S. Geary et al.   ADVANCED DRUG DELIVERY REVIEWS

LC–MS of oligonucleotides: applications in biomedical research

(2014) Babak Basiri et al.   Bioanalysis

Quantification of oligonucleotides by LC–MS/MS: the challenges of quantifying a phosphorothioate oligonucleotide and multiple metabolites

(2014) Matthew Ewles et al.   Bioanalysis

Phosphorothioate Oligonucleotide Quantification by μ-Liquid Chromatography-Mass Spectrometry

(2012) Robert Erb et al.   AAPS Journal

OMA and OPA—Software-Supported Mass Spectra Analysis of Native and Modified Nucleic Acids

(2012) Adrien Nyakas et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Alternating 2′-O-ribose methylation is a universal approach for generating non-stimulatory siRNA by acting as TLR7 antagonist

(2009) Svetlana Hamm et al.   IMMUNOBIOLOGY

Stem-Loop RT-PCR Quantification of siRNAs In Vitro and In Vivo

(2009) Angie Cheng et al.   OLIGONUCLEOTIDES