Barrier Protection and Recovery Effects of Gut Commensal Bacteria on Differentiated Intestinal Epithelial Cells In Vitro

The human gut Firmicute Roseburia intestinalis is a primary degrader of dietary β-mannans

(2019) Sabina Leanti La Rosa et al.   Nature Communications

Roseburia intestinalis inhibits oncostatin M and maintains tight junction integrity in a murine model of acute experimental colitis

(2019) Bei Tan et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Targeting immune cell circuits and trafficking in inflammatory bowel disease

(2019) Markus F. Neurath   NATURE IMMUNOLOGY

Insights into Roseburia intestinalis which alleviates experimental colitis pathology by inducing anti-inflammatory responses

(2018) Zhaohua Shen et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Faecalibacterium prausnitzii and a Prebiotic Protect Intestinal Health in a Mouse Model of Antibiotic and Clostridium difficile Exposure

(2018) Sanjoy Roychowdhury et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Roseburia intestinalis inhibits interleukin‑17 excretion and promotes regulatory T cells differentiation in colitis

(2018) Changxin Zhu et al.   Molecular Medicine Reports

Relationship between intestinal microbiota and ulcerative colitis: Mechanisms and clinical application of probiotics and fecal microbiota transplantation

(2018) Zhao-Hua Shen et al.   WORLD JOURNAL OF GASTROENTEROLOGY

The Potential of Gut Commensals in Reinforcing Intestinal Barrier Function and Alleviating Inflammation

(2018) Kaisa Hiippala et al.   Nutrients

Alterations in the Abundance and Co-occurrence of Akkermansia muciniphila and Faecalibacterium prausnitzii in the Colonic Mucosa of Inflammatory Bowel Disease Subjects

(2018) Mireia Lopez-Siles et al.   Frontiers in Cellular and Infection Microbiology

Adhesion Properties of Food-Associated Lactobacillus plantarum Strains on Human Intestinal Epithelial Cells and Modulation of IL-8 Release

(2018) Natalia Garcia-Gonzalez et al.   Frontiers in Microbiology

Faecalibacterium prausnitzii: from microbiology to diagnostics and prognostics

(2017) Mireia Lopez-Siles et al.   ISME Journal

Gut microbiota and IBD: causation or correlation?

(2017) Josephine Ni et al.   Nature Reviews Gastroenterology & Hepatology

Effects of Supernatants from Escherichia coli Nissle 1917 and Faecalibacterium prausnitzii on Intestinal Epithelial Cells and a Rat Model of 5-Fluorouracil-Induced Mucositis

(2017) Hanru Wang et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Functional Characterization of Novel Faecalibacterium prausnitzii Strains Isolated from Healthy Volunteers: A Step Forward in the Use of F. prausnitzii as a Next-Generation Probiotic

(2017) Rebeca Martín et al.   Frontiers in Microbiology

Butyrate-producing bacteria supplemented in vitro to Crohn’s disease patient microbiota increased butyrate production and enhanced intestinal epithelial barrier integrity

(2017) Annelies Geirnaert et al.   Scientific Reports

Navigating the Microbial Basis of Inflammatory Bowel Diseases: Seeing the Light at the End of the Tunnel

(2016) Laura E. Raffals et al.   Gut and Liver

Lower Level of Bacteroides in the Gut Microbiota Is Associated with Inflammatory Bowel Disease: A Meta-Analysis

(2016) Yingting Zhou et al.   Biomed Research International

Outer Membrane Vesicles and Soluble Factors Released by Probiotic Escherichia coli Nissle 1917 and Commensal ECOR63 Enhance Barrier Function by Regulating Expression of Tight Junction Proteins in Intestinal Epithelial Cells

(2016) Carina-Shianya Alvarez et al.   Frontiers in Microbiology

Identification of Metabolic Signatures Linked to Anti-Inflammatory Effects of Faecalibacterium prausnitzii

(2015) Sylvie Miquel et al.   mBio

A simple coculture system shows mutualism between anaerobic faecalibacteria and epithelial Caco-2 cells

(2015) Mehdi Sadaghian Sadabad et al.   Scientific Reports

Treatment of IBD: Where We Are and Where We Are Going

(2014) Charles N Bernstein   AMERICAN JOURNAL OF GASTROENTEROLOGY

Exploring & exploiting our ‘other self’ – Does the microbiota hold the key to the future therapy in Crohn's?

(2014) Lea-Maxie Haag et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

The HMI™ module: a new tool to study the Host-Microbiota Interaction in the human gastrointestinal tract in vitro

(2014) Massimo Marzorati et al.   BMC MICROBIOLOGY

Lactobacillus GG restoration of the gliadin induced epithelial barrier disruption: the role of cellular polyamines

(2014) Antonella Orlando et al.   BMC MICROBIOLOGY

The Integrative Human Microbiome Project: Dynamic Analysis of Microbiome-Host Omics Profiles during Periods of Human Health and Disease

(2014)   Cell Host & Microbe

LiveFaecalibacterium prausnitziiin an apical anaerobic model of the intestinal epithelial barrier

(2014) Dulantha Ulluwishewa et al.   CELLULAR MICROBIOLOGY

Mucosa-associated Faecalibacterium prausnitzii and Escherichia coli co-abundance can distinguish Irritable Bowel Syndrome and Inflammatory Bowel Disease phenotypes

(2014) Mireia Lopez-Siles et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Future directions in inflammatory bowel disease management

(2014) Geert R. D'Haens et al.   Journal of Crohns & Colitis

Understanding How Commensal Obligate Anaerobic Bacteria Regulate Immune Functions in the Large Intestine

(2014) Eva Maier et al.   Nutrients

Colonic bacterial metabolites and human health

(2013) Wendy R Russell et al.   CURRENT OPINION IN MICROBIOLOGY

Faecalibacterium prausnitzii and human intestinal health

(2013) S Miquel et al.   CURRENT OPINION IN MICROBIOLOGY

Roseburia hominis: a novel guilty player in ulcerative colitis pathogenesis?

(2013) Herbert Tilg et al.   GUT

A decrease of the butyrate-producing speciesRoseburia hominisandFaecalibacterium prausnitziidefines dysbiosis in patients with ulcerative colitis

(2013) Kathleen Machiels et al.   GUT

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Lactobacilli Reduce Chemokine IL-8 Production in Response to TNF-αandSalmonellaChallenge of Caco-2 Cells

(2013) Da-Yong Ren et al.   Biomed Research International

From meta-omics to causality: experimental models for human microbiome research

(2013) Joëlle V Fritz et al.   Microbiome

Regulation of intestinal epithelial permeability by tight junctions

(2012) Takuya Suzuki   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanisms of tumor necrosis factor-alpha-induced leaks in intestine epithelial barrier

(2012) Fang He et al.   CYTOKINE

Intestinal colonization resistance

(2012) Trevor D. Lawley et al.   IMMUNOLOGY

Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow

(2012) Hyun Jung Kim et al.   LAB ON A CHIP

Diversity, stability and resilience of the human gut microbiota

(2012) Catherine A. Lozupone et al.   NATURE

Interactions Between the Microbiota and the Immune System

(2012) L. V. Hooper et al.   SCIENCE

Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives

(2011) M. Joossens et al.   GUT

Dynamics of adherens junctions in epithelial establishment, maintenance, and remodeling

(2011) Buzz Baum et al.   JOURNAL OF CELL BIOLOGY

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Unexpected role of anticoagulant protein C in controlling epithelial barrier integrity and intestinal inflammation

(2011) S. Vetrano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of human epithelial tight junction proteins by Lactobacillus plantarum in vivo and protective effects on the epithelial barrier

(2010) Jurgen Karczewski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Effect of live Lactobacillus plantarum L2 on TNF-α-induced MCP-1 production in Caco-2 cells

(2010) Bin Wang et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Epithelial crosstalk at the microbiota-mucosal interface

(2010) J. M. Wells et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An In Vitro Study on Bacterial Growth Interactions and Intestinal Epithelial Cell Adhesion Characteristics of Probiotic Combinations

(2009) Mahta Moussavi et al.   CURRENT MICROBIOLOGY

Low counts of Faecalibacterium prausnitzii in colitis microbiota

(2009) H. Sokol et al.   INFLAMMATORY BOWEL DISEASES

Effects of probiotics and commensals on intestinal epithelial physiology: implications for nutrient handling

(2009) Silvia C. Resta   JOURNAL OF PHYSIOLOGY-LONDON

Endoplasmic reticulum stress and intestinal inflammation

(2009) A Kaser et al.   Mucosal Immunology

Probiotics ameliorate the hydrogen peroxide-induced epithelial barrier disruption by a PKC- and MAP kinase-dependent mechanism

(2008) A. Seth et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Changes in the expression of claudins in active ulcerative colitis

(2008) Tadayuki Oshima et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Mucins in the mucosal barrier to infection

(2008) S K Linden et al.   Mucosal Immunology

Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

(2008) H. Sokol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA