Article
Surgery
Mauricio de Maio
Summary: The MD Codes system is a universal symbolic language for reducing variability in injection technique to focus on both lessening unfavorable facial attributes and enhancing positive ones, ultimately improving patient satisfaction with treatment outcomes.
AESTHETIC PLASTIC SURGERY
(2021)
Article
Dermatology
Farzaneh Akbari, Maryam Hadibarhaghtalab, Seyedeh Yasamin Parvar, Sara Dehghani, Mohammad Reza Namazi
Summary: This study aimed to investigate the therapeutic effect of intradermal injection of nano fat on fine facial wrinkles and assess their changes over 7 months of follow-up.
JOURNAL OF COSMETIC DERMATOLOGY
(2023)
Article
Medicine, General & Internal
Stefania Belletti, Francesca Madeddu, Antonino Brando, Eugenio Provenzano, Steven Paul Nistico, Irene Fusco, Luigi Bennardo
Summary: This study assessed the efficacy of a new laser device that combines CO2 and 1540 nm wavelengths for wrinkles reduction. The results showed that this dual-wavelength laser technique is a promising option for safe and nonsurgical skin rejuvenation with low risk of scarring or hypopigmentation and shorter healing times.
MEDICINA-LITHUANIA
(2023)
Article
Dermatology
Lehavit Akerman, Moshe Lapidoth, Assi Levi, Eran Sharon, Daniel Hilewitz, Efrat Solomon-Cohen
Summary: The study evaluated the safety and efficacy of the combination treatment of QSF-Nd:YAG laser and non-fractional microsecond pulsed technology for skin rejuvenation. The results showed that this combination treatment resulted in mild improvements in facial erythema and wrinkles, with mild and transient pain perception and adverse effects, and high patient satisfaction.
JOURNAL OF COSMETIC DERMATOLOGY
(2021)
Article
Dermatology
Huray Hugul, Muazzez Cigdem Oba, Murat Kirisci, Zekayi Kutlubay
Summary: The study demonstrates that the combined focused radiofrequency and ultrasound therapy is an effective and safe method for rejuvenation of different sub-areas of the face and neck, with high patient satisfaction scores. Significant reduction in wrinkle/sagging scores was observed in seven anatomical regions after the treatment.
JOURNAL OF COSMETIC DERMATOLOGY
(2022)
Article
Nutrition & Dietetics
Iryna Rybak, Alexis E. Carrington, Simran Dhaliwal, Aliza Hasan, Hera Wu, Waqas Burney, Jessica Maloh, Raja K. Sivamani
Summary: The study demonstrates that daily consumption of almonds can improve several aspects of photoaging such as facial wrinkles and pigment intensity in postmenopausal women.
Article
Dermatology
Jessica Mineroff, Evan Austin, Eric Feit, Anthony Ho, Brian Lowe, Justin Marson, Jacob Mojeski, Todd Wechter, Julie K. Nguyen, Jared Jagdeo
Summary: Home-based photobiomodulation is an effective and convenient treatment option for improving the appearance and texture of the skin. A combination of red light and near-infrared light has been specifically designed to target male skin. A study assessing the safety and efficacy of a LED facemask showed favorable results, with participants reporting improvements in fine lines, wrinkles, skin texture, and overall satisfaction after 6 weeks of treatment.
ARCHIVES OF DERMATOLOGICAL RESEARCH
(2023)
Review
Biochemistry & Molecular Biology
Li Ting Kee, Chiew Yong Ng, Maimonah Eissa Al-Masawa, Jhi Biau Foo, Chee Wun How, Min Hwei Ng, Jia Xian Law
Summary: Extracellular vesicles (EVs) have great potential as nanocarriers in facial aesthetics, improving skin conditions such as scar removal, facial rejuvenation, anti-aging, and anti-pigmentation. However, more research is needed to establish a large-scale EV production platform and understand the mechanism of action for improved efficacy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Dermatology
Arielle N. B. Kauvar, Amikam Gershonowitz
Summary: The study evaluated the safety and effectiveness of using a fractional RF device with 1.0 mm long ultrathin electrode tips for improving facial skin texture and wrinkles. After six treatment sessions, participants showed improvement in skin texture and wrinkles without experiencing any adverse events or downtime during the treatment process.
LASERS IN SURGERY AND MEDICINE
(2022)
Review
Medicine, Research & Experimental
Shirin Bajaj, David Orbuch, Jordan Wang, Roy G. Geronemus
Summary: Platelet-rich plasma (PRP) has gained popularity in the field of cutaneous rejuvenation, but standardized literature evaluating its efficacy and best practices is lacking. Existing high-quality evidence suggests subtle to modest clinical improvement with PRP for facial rejuvenation, although conflicting results are seen in many studies. Further high-quality research with well-defined methodologies is needed to better understand the role of PRP.
ADVANCES IN THERAPY
(2022)
Article
Dermatology
Afsaneh Marefat, Sahar Dadkhahfar, Azin Tahvildari, Reza M. Robati
Summary: This study examined the effectiveness of PCL filler on enlarged facial pores, showing a significant reduction in pore size after treatment but no significant improvement in skin evenness, red areas, UV spots, and wrinkles.
DERMATOLOGIC THERAPY
(2022)
Article
Multidisciplinary Sciences
Xue Liu, Rebecca Barresi, Michael Kaminer, Kun Qian, Fabienne Thillou, Michel Bataillon, I-Chien Liao, Qian Zheng, Charbel Bouez
Summary: This study developed an ex vivo tissue model to simulate the microneedling procedure and elucidate its mechanism of action. It was found that microneedling treatment stimulated skin proliferation and barrier renewal, while also increasing the levels of inflammatory cytokines and angiogenic growth factors. Morphological and molecular changes indicated the regeneration of the epidermis in the treated skin.
SCIENTIFIC REPORTS
(2022)
Article
Dermatology
Efrat Solomon-Cohen, Moshe Lapidoth, Daniel Mimouni, Lehavit Akerman, Dan Slodownik, Emmilia Hodak, Assi Levi
Summary: The study evaluated the safety and efficacy of high-fluence, nonablative 1540-nm fractionated erbium:glass laser treatment for facial rejuvenation. After 3-4 treatments, patients showed moderate-to-significant improvement in wrinkles appearance in both frontal face and lateral canthal region, with high satisfaction reported.
JOURNAL OF COSMETIC DERMATOLOGY
(2021)
Article
Engineering, Biomedical
Ashraf Badawi, Tarek Sobeih, Vesel Jasmina
Summary: The study evaluated the safety and efficacy of non-ablative long-pulse 2940 nm Er:YAG laser for periorbital static wrinkles and skin laxity. Treatment involved three sessions over a 3-month period, resulting in significant improvement in periorbital wrinkles classification and lasting efficacy up to 1 year.
LASERS IN MEDICAL SCIENCE
(2022)
Review
Dermatology
Danny Daniely, Harryono Judodihardjo, Sajjad F. Rajpar, Joseph N. Mehrabi, Ofir Artzi
Summary: The study on Thermo-mechanical fractional injury (TMFI) therapy showed overall improvement in facial skin rejuvenation, with the greatest enhancements seen in skin complexion, periorbital wrinkles, and vitality. Transient side effects such as erythema and hyperpigmentation were observed with an average downtime of 1.7 days.
LASERS IN SURGERY AND MEDICINE
(2021)
Letter
Surgery
Leonie Schelke, Sebastian Cotofana, Peter Velthuis
AESTHETIC SURGERY JOURNAL
(2023)
Article
Surgery
Mariana Calomeni, Bruna S. F. Bravo, Leonie W. Schelke, Peter J. Velthuis, Grant Schalet, Konstantin Frank, Anne Guertler, Michael Alfertshofer, Sebastian Cotofana, Nicholas Moellhoff
Summary: This study assessed the precision of facial filler injections using a cannula and found that the use of a cannula allows accurate application of the product in the intended tissue plane. Precision can be improved by injecting smaller amounts of product into deeper tissue layers.
AESTHETIC SURGERY JOURNAL
(2023)
Article
Surgery
Gabriela Casabona, Michael Alfertshofer, Kai Kaye, Konstantin Frank, Nicholas Moellhoff, Kristina Davidovic, Sebastian Cotofana
Summary: By using real-time ultrasound imaging, this study analyzed the integration and distribution behavior of six different biostimulator substances in subcutaneous soft tissues. The results showed that some substances spread more after massaging, while others showed better tissue integration.
AESTHETIC SURGERY JOURNAL
(2023)
Editorial Material
Surgery
Sebastian Cotofana, Leonie W. Schelke, Peter J. Velthuis
AESTHETIC SURGERY JOURNAL
(2023)
Article
Surgery
Michael Alfertshofer, Nina Engerer, Konstantin Frank, Nicholas Moellhoff, David L. Freytag, Sebastian Cotofana
Summary: This study investigated age-related changes in the biomechanical unit formed by facial muscles, connective tissue envelope, and skin in the upper face. The results showed that as people age, the skin becomes less firm and elastic, and there is increased vertical skin mobility. Additionally, there is a decrease in surface-derived electromyography signal of the frontalis muscle. These findings are important for targeted and individualized aesthetic treatments.
AESTHETIC SURGERY JOURNAL
(2023)
Article
Dermatology
Sabrina Guillen Fabi, Claudia Hernandez, Jose Raul Montes, Sebastian Cotofana, Steve Dayan
Summary: The Hispanic/Latin American population is the fastest growing non-Caucasian group in the United States and has an increasing demand for aesthetic procedures. Understanding the ethnic differences in anatomy and treatment preferences of Hispanic/Latin American patients is crucial for providing optimal care.
JOURNAL OF COSMETIC DERMATOLOGY
(2023)
Article
Dermatology
Said Hilton, Konstantin Frank, Michael Alfertshofer, Sebastian Cotofana
Summary: This study aimed to evaluate the safety and effectiveness of lip injections using two hyaluronic acid (HA) fillers manufactured with different gel technologies. Subjects treated with HA(RK) experienced lower intensity of early onset swelling, erythema, and pain/tenderness compared to subjects treated with HA(JUS). Aesthetic improvement, subject satisfaction, and adverse event profiles post-Day 14 were similar between the two filler groups.
JOURNAL OF COSMETIC DERMATOLOGY
(2023)
Review
Surgery
Samuel Knoedler, Giuseppe Sofo, Barbara Kern, Konstantin Frank, Sebastian Cotofana, Sarah von Isenburg, Soren Konneker, Francesco Mazzarone, Amir H. Dorafshar, Leonard Knoedler, Michael Alfertshofer
Summary: This study compared real patient feedback with ChatGPT-generated reviews for the top five US plastic surgery procedures. It found that analyzing the emotional tone and review length can help differentiate real from fake reviews, and ChatGPT-generated reviews can convincingly deceive commercial AI detection software.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2024)
Article
Dermatology
L. Schelke, O. Liplavk, S. Cotofana, S. Shah-Desai, P. Velthuis
Summary: This study evaluated patients with malar edema after hyaluronic acid filler treatment and found that filler material was mainly located inside the SMAS. With duplex-ultrasound guided filler removal, clinical improvement of malar edema was observed minutes after treatment.
JOURNAL OF COSMETIC DERMATOLOGY
(2023)
Article
Dermatology
Leonie Schelke, Steve Harris, Hugues Cartier, Michael Alfertshofer, Marwah Doestzada, Sebastian Cotofana, Peter J. Velthuis
Summary: This study demonstrates the identification, evaluation, and treatment of facial overfilled syndrome using facial ultrasound and simultaneous hyaluronidase injections. Targeted hyaluronidase injections have shown to restore a natural smile, reduce excess midfacial volume, and decrease the severity of lateral canthal lines.
JOURNAL OF COSMETIC DERMATOLOGY
(2023)
Article
Dermatology
Marcelo Germani, Claudia C. M. S. Almeida, Victor R. M. Munoz-Lora, Victor Rogerio, Nicholas Moelhoff, David L. Freytag, Jeremy B. Green, Michael Alfertshofer, Kristina Davidovic, Sebastian Cotofana
Summary: This study aimed to evaluate whether the severity of infraorbital hollows can be improved by injecting neuromodulators in the supra-mandibular segment of the platysma. The results showed that the Toxin Lift injection technique can significantly improve the clinical appearance of infraorbital hollows.
JOURNAL OF COSMETIC DERMATOLOGY
(2023)
Review
Dermatology
Andreas Nikolis, Kaitlyn M. Enright, Philippe Berros, John S. Samaplis
Summary: This study evaluated the safety of hyaluronic acid injections for aesthetic rejuvenation in the infraorbital region. The results showed that there are differences in adverse event rates between needle and cannula injections, with needles being associated with a higher risk of ecchymosis and cannulas being associated with a higher risk of edema. These findings should be discussed with patients before treatment consultation.
JOURNAL OF COSMETIC DERMATOLOGY
(2023)
Article
Surgery
Andreas Nikolis, Kaitlyn M. Enright, Quynh Nguyen, Hani. H. H. Sinno, Sebastian Cotofana
Summary: A clinical trial was conducted to evaluate the use of HA-L in non-surgical rhinoplasty. The results demonstrated that HA-L is a safe and effective option for injection rhinoplasty, meeting the expectations of the subjects.
Article
Dermatology
Joanna Kempa, Michael Alfertshofer, Arthur Swift, Jeremy B. Green, Boguslaw Antoszewski, Wojciech Timler, Sebastian Cotofana, Anna Kasielska-Trojan
Summary: Instead of a single universal ratio, this study found that multiple facial proportions exist that are perceived as most attractive/masculine/feminine. The most attractive male/female face is not necessarily the most masculine or feminine.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2023)