Article
Chemistry, Physical
S. Meskinis, A. Vasiliauskas, R. Gudaitis, M. Andrulevicius, A. Guobiene
Summary: Graphene was synthesized directly on the Si(1 0 0) substrate using an Inductively Coupled Plasma Beam Source without any catalyst. The effects of plasma power, methane gas flow, hydrogen gas flow, temperature, and time on the number of graphene layers, flake size, defects density, and surface morphology were studied. The growth of graphene was influenced by the competition between graphene growth, hydrogen etching, hydrogenation, and thermal stress release.
APPLIED SURFACE SCIENCE
(2022)
Article
Spectroscopy
Marketa Hola, Karel Novotny, Jan Dobes, Ivo Krempl, Vojtech Wertich, Juraj Mozola, Martin Kubes, Veronika Faltusova, Jaromir Leichmann, Viktor Kanicky
Summary: The study demonstrated the great potential of combining LIBS and LA-ICP-MS imaging techniques, providing advantages of high speed, large area imaging, high resolution, and low detection limits. A special software, ILAPS, was created to ensure data processing consistency, effectively identifying structures responsible for elements migration in uranium ore samples.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2021)
Editorial Material
Food Science & Technology
Jerzy Falandysz
Summary: Lanthanides, known as rare earth elements, are found in plant and animal foods, including edible wild mushrooms, at very low concentrations. The collective reporting of lanthanides as a summed value (REE) may result in relatively high concentrations due to the high contributions from individual elements. These elements naturally occur in environmental media, such as the soil substrate, and follow a characteristic pattern in fungi. Therefore, abnormalities should be closely examined and resolved.
FOOD ANALYTICAL METHODS
(2023)
Article
Nuclear Science & Technology
Yunqiu Cui, Na Lu, Chunjie Niu, Jianhua Lv, Weifeng Liu, Chao Chen, Weiyuan Ni, Xianxiu Mei, Guangjiu Lei, Jiupeng Song, Miao Zhao, Hongyu Fan, Dongping Liu
Summary: In this study, the evolution of hydrogen bubbles in Mo during different annealing processes was investigated through experiments and simulations. The results showed that the size and density of hydrogen bubbles increased with the increase of hydrogen ion fluence, and annealing temperature had an effect on bubble growth and evolution.
NUCLEAR MATERIALS AND ENERGY
(2022)
Article
Nanoscience & Nanotechnology
Sang-Woo Kim, Ju-Hong Cha, Sung-Hyeon Juing, SeungBo Shim, Chang Ho Kim, Ho-Jun Lee
Summary: This study proposes a novel inductively coupled plasma (ICP) system consisting of a segmented dielectric window and a metal frame. The thin window design compensates for power loss caused by the metal frame, enhancing the controllability of the gas flow field and reducing capacitive power coupling. Three-dimensional fluid self-consistent plasma simulations and experiments confirm the superior uniformity and reliability of the proposed ICP system for semiconductor processes, comparable to conventional ICP systems used in etching and deposition.
Article
Food Science & Technology
Dorota Jakkielska, Ioannis Dasteridis, Maciej Kubicki, Marcin Frankowski, Anetta Ziola-Frankowska
Summary: The research aimed to evaluate the impact of various factors on the concentration of 26 elements in Polish wine samples. It was found that white wines had higher levels of certain elements, including Al, Cu, and Fe, while red wines had higher concentrations of Ba, Mn, and Sr. Additionally, the study confirmed that the analyzed elements did not pose a health risk to wine consumers.
Article
Biochemistry & Molecular Biology
Adil Hussain, Muhammad Sajid, Daniel Potter, Hassam Rasheed, Mujtaba Hassan, Naeem Akhtar, Bashir Ahmad, Syed Ali Imran Bokhari
Summary: Diversity in eleven Artemisia species from northern Pakistan was assessed based on elemental contents. Cluster analysis divided the species into two groups, while PCA analysis revealed maximum species diversity in the second axis. The study highlights the importance of precautionary measures to avoid metal toxicity when using Artemisia as medication.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Article
Chemistry, Analytical
Nicole M. Ralbovsky, Lanfang Zou, Bingming Chen, Nanyan Rena Zhang, Catherine D. G. Hines, Marissa Vavrek, Wendy Zhong, Joseph P. Smith, Xiaodong Bu
Summary: Spatial distribution analysis of metals, metalloids, and non-metals in biological tissues is important in life sciences to understand their roles in biological pathways. Chemical imaging methods can reveal individual spatial distributions of analytes, while LA-ICP-MS is effective for direct elemental analysis with high precision.
Article
Environmental Sciences
Atia Gohar, Muhammad Shakeel
Summary: The study found that the elemental composition in honey is significantly influenced by environmental factors of the geographical regions, and the quality of honey is affected by a variety of factors, among which the concentrations of essential and toxic elements vary greatly.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Spectroscopy
Isabela Meirelles de Souza Ferreira, Bernardo Ferreira Braz, Ladario da Silva, Aderval Severino Luna, Ricardo Erthal Santelli
Summary: This study developed a new method combining LA-ICP-MS technology and tape-lift collection for forensic analysis of Gunshot Residue (GSR). By comparing samples from shooters and non-shooters, a fast and effective discrimination method was proposed, providing important assistance for criminal identification.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2021)
Article
Chemistry, Analytical
Jelena Mrmosanin, Aleksandra Pavlovic, Ivana Rasic Misic, Snezana Tosic, Stefan Petrovic, Zorica Mitic, Emilija Pecev-Marinkovic, Biljana Arsic
Summary: This study aimed at optimizing the ICP-AES conditions for the determination of macro and microelements in Trifolium species flowers and leaves. Plasma robustness was achieved after the optimization of instrumental parameters. The most abundant microelement in leaves was Ca, while in flowers it was K. The average contents of microelements were then determined and chemometrics were used for sample grouping based on elemental contents.
ANALYTICAL LETTERS
(2023)
Article
Chemistry, Analytical
N. Manousi, N. P. Kalogiouri, L. Kokokiris, A. Anthemidis, G. A. Zachariadis
Summary: Flower waters, considered by-products of essential oils, have various applications in the food industry due to their bioactive content. This study utilized ICP-AES to assess the elemental composition of several flower waters, with an optimized and validated method.
ANALYTICAL LETTERS
(2022)
Article
Multidisciplinary Sciences
E. Ph. Galay, R. V. Dorogin, A. Z. Temerdashev
Summary: This paper discusses the presence and control methods of cobalt and nickel in human biological fluids, compares different sample preparation methods, and evaluates their measurement characteristics. The study shows that taking vitamin complexes in therapeutic concentrations does not lead to a significant increase in trace element concentrations in urine, while elevated concentrations can be detected using ICP-AES.
Article
Biochemistry & Molecular Biology
Akif Ari, Pelin Erturk Ari, Donus Ermiser, Betul Cindik, Erkan Yalcin, Eftade O. Gaga
Summary: The study optimized an analytical method for quantifying 57 elements using ICP-MS/MS and validated it for 25 elements, showing good precision. Analyzed elements showed significant variability among semolina samples, likely influenced by variety and growing conditions.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2022)
Article
Nanoscience & Nanotechnology
Wilton J. M. Kort-Kamp, Ryan A. Murdick, Han Htoon, Andrew C. Jones
Summary: Akiyama atomic force microscopy probes combine the advantages of tuning fork and cantilever probe designs, allowing for multi-modal force sensing of nanoscale photothermal response.
Review
Nanoscience & Nanotechnology
Raees Khan, Alyson L. Yee, Jack A. Gilbert, Adnan Haider, Syed Babar Jamal, Fawad Muhammad
Summary: This review discusses the safety and antimicrobial resistance concerns associated with the use of TCS-containing sutures, emphasizing the importance of evaluating long-term health benefits before incorporation.
APPLIED NANOSCIENCE
(2022)
Review
Nanoscience & Nanotechnology
Murtada A. Oshi, Adnan Haider, Muhammad Irfan Siddique, Alam Zeb, Syed Babar Jamal, Atif Ali Khan Khalil, Muhammad Naeem
Summary: Nanomedicine, the medical application of nanotechnology, has shown promise in treating inflammatory disorders by using engineered nanomaterials to deliver drugs precisely without harming healthy cells. Extensive research has been conducted to validate the positive impact of nanomedicine on inflammation treatment, and future prospects of using nanomaterials for inflammatory diseases are discussed briefly.
APPLIED NANOSCIENCE
(2022)
Article
Nanoscience & Nanotechnology
Iqra Riasat, Syeda Marriam Bakhtiar, Muhammad Faheem, Arun Kumar Jaiswal, Muhammad Naeem, Raees Khan, Asmat Ullah Khan, Atif Ali Khan Khalil, Adnan Haider, Muhammad Junaid, Siomar de Castro Soares, Vasco Azevedo, Sandeep Tiwari, Syed Babar Jamal
Summary: This study utilized the pan genome to develop drug targets for 51 strains of Clostridium botulinum, selecting 7 essential proteins and docking them against 105 antibacterial compounds. The top 10 compounds with the highest binding affinity and number of interactions were chosen, with 39 promising compounds identified for further validation and clinical trials.
APPLIED NANOSCIENCE
(2022)
Article
Chemistry, Analytical
Nargis Jamila, Naeem Khan, In Min Hwang, Yu Min Park, Ga Hyun Lee, Ji Yeon Choi, Min Ja Cho, Kyung Su Park, Kyong Su Kim
Summary: This study examined the concentrations of toxic metals in commonly consumed crustaceans from South Korea and found that the levels were within safe limits for consumers.
ANALYTICAL LETTERS
(2022)
Article
Chemistry, Analytical
Ji Young Jeong, Md Atikul Islam, Naeem Khan, Nargis Jamila, Joon Ho Hong, Kyong Su Kim
Summary: The study compared the volatile organic compounds (VOCs) among three varieties of Perilla frutescens leaves from South Korea and found that the P. frutescens for. viridis Makino leaves contained the highest concentrations of VOCs. Differences in the patterns of functional groups and terpene types were demonstrated among the varieties. SDE provided more compounds while HS-SPME was more convenient for the determination.
ANALYTICAL LETTERS
(2022)
Article
Chemistry, Analytical
Nargis Jamila, In Min Hwang, Yu Min Park, Ga Hyun Lee, Ji Yeon Choi, Naeem Khan, Min Ja Cho, Kyung Su Park, Kyong Su Kim
Summary: This study reports the concentrations of As, Cd, Hg, and Pb in commonly consumed crustaceans collected from South Korea. The techniques used for analysis were validated, and the study also carried out risk assessment to determine the potential threat of these crustaceans to consumers. It was found that under normal circumstances, these crustaceans do not pose a threat to consumers.
ANALYTICAL LETTERS
(2023)
Article
Materials Science, Multidisciplinary
Umar Nishan, Hameed Ullah Khan, Abdur Rahim, Muhammad Asad, Mughal Qayum, Naeem Khan, Mohibullah Shah, Nawshad Muhammad
Summary: Nitrite detection in processed meat products is important due to its acknowledged toxicity. In this study, manganese dioxide nanoparticles were synthesized using a drug-mediated method and used for colorimetric detection of nitrite. By coating the nanoparticles and optimizing reaction conditions, the proposed sensor showed high sensitivity and a wide linear range for nitrite detection. This method has practical significance for monitoring nitrite levels in bacon chicken meat products.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Biology
Wajheeba Khan, Naeem Khan, Nargis Jamila, Rehana Masood, Aaliya Minhaz, Farhat Amin, Amir Atlas, Umar Nishan
Summary: This study successfully synthesized silver nanoparticles using aqueous extracts of Rhus javanica, Rumex hastatus, and Callistemon viminalis. The structural and size analysis of the synthesized nanoparticles was confirmed using spectroscopic techniques and microscopy. The synthesized silver nanoparticles showed potential free radical scavenging, antibacterial, and catalytic properties, suggesting their promising role in drug development and remediation of industrial effluents.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2022)
Article
Polymer Science
Niaz Ali Khan, Amjad Khan, Rooh Ullah, Majeed Ullah, Amal Alotaibi, Riaz Ullah, Adnan Haider
Summary: The aim of this study was to prepare and characterize a sustained-release matrix tablet containing a high-dose hydrophobic drug using HPMC as the matrix-forming polymer. The results showed that HPMC successfully sustained drug release for 24 hours, and the physical parameters and drug content of the tablets were within the pharmacopeial limits.
Review
Nanoscience & Nanotechnology
Rameesha Abid, Muhammad Khurram Shahzad, Samra Muhammad Sulaman, Muhammad Faheem, Muhammad Naeem, Raees Khan, Atif Ali Khan Khalil, Adnan Haider, Bilal Ahmad, Rukhsana Gul, Nausheen Bukhari, Syed Babar Jamal
Summary: The diagnosis of novel coronavirus (COVID-19) has gained global attention since December 2019. Early diagnosis of the coronavirus is crucial for prevention and control, with implementing suppression strategies being essential to eradicating the pandemic and saving more lives. Various testing technologies have been developed for rapid and accurate detection, with molecular tests playing a key role in confirming coronavirus infection.
APPLIED NANOSCIENCE
(2022)
Article
Chemistry, Analytical
Md Atikul Islam, Ji Young Jeong, Eun Ju Kim, Naeem Khan, Nargis Jamila, Kyong Su Kim
Summary: This study analyzed the elemental composition of chicken breast meat from conventional and sustainable farms in South Korea. The results showed that the sustainable samples had higher levels of zinc, strontium, barium, selenium, lithium, and gallium, while the levels of trace and toxic elements were lower compared to recommended standards.
ANALYTICAL LETTERS
(2023)
Review
Materials Science, Multidisciplinary
Sohee Kang, Adnan Haider, Kailash Chandra Gupta, Hun Kim, Innkyu Kang
Summary: Hydroxyapatite (HA) is an important component of artificial bone grafts, but its poor dispersibility and tendency to form aggregates pose challenges. Chemical bonding of biologically active molecules is suggested to modify the HA surface to prevent aggregation and achieve homogeneous dispersion. Irradiation is shown to produce bioactive and antibacterial nanosized hydroxyapatite (nHA) by inducing morphological variations and reactive oxygen species formation. Furthermore, small molecules such as proteins, peptides, drugs, and photocatalysts play a significant role in modifying the surface properties of nHA for stable and bioactive artificial bone implants.
Article
Chemistry, Analytical
Md Atikul Islam, Ji Young Jeong, Md Selim Hossain, Hasan Tarek, Naeem Khan, Nargis Jamila, Kyong Su Kim
Summary: The aim of this study was to optimize the ultrasonic-assisted extraction (UAE) method for the extraction of polyphenols, antioxidants, antibacterials, and cytotoxic activities from five varieties of Piper betle L. leaves from Bangladesh. The UAE method was optimized using single-factor experimentation and central composite circumscribed design. The optimal conditions were determined to be 70:5:25 ethanol:acetic acid:water and a solid/liquid ratio of 1:15.41, with an extraction time of 90 min at 75 degrees C. The results showed significant antioxidant activity and good antibacterial properties and cytotoxicity against cancer cells, indicating that UAE is suitable for extracting polyphenolics from betel leaves.
ANALYTICAL LETTERS
(2023)
Article
Plant Sciences
Bihua Chen, Juan Zhang, Junjie Wu, Jianmin Li, Huihua Fan
Summary: The harvest time for Gardenia jasminoides fruit in Fujian China is generally from October to November. Placing the seeds in the shade or refrigerator can improve the seedling height increment but not the germination rate. By comparing different plant growth regulator concentrations, 500 ppm of 3-indolebutyric acid (IBA) was found to be suitable for G. jasminoides cutting propagation. The tissue-cultured seedlings showed early flowering performance and advanced fruiting after afforestation.
PAKISTAN JOURNAL OF BOTANY
(2023)
Article
Chemistry, Multidisciplinary
Wafa A. Bawazir, Maymoona A. Al-Mahmood, Rawan S. Almalki, Ghadi F. Alofi, Raghad S. Alharbi, Zoya Zaheer
Summary: This study investigates the interaction between sulfathiazole and three types of surfactants using UV-visible spectroscopy and conductivity measurements. The results show that the critical micelle concentration of cationic and anionic surfactants decreases with increasing sulfathiazole concentration, while the interaction with non-ionic surfactant is weak.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Musaad K. Aleid, Khalid N. Alharbi, Mona A. Aljufareen, Areej S. Aloliwi, Alhanouf K. Almutairi, Rahaf S. Alsaif, Nada K. Alshayeb, Mohammed S. Almoiqli
Summary: This study assessed the levels of trihalomethane compounds in the water network of Riyadh city and identified the factors influencing their formation. The concentrations of trihalomethane compounds were within the permissible limits, indicating the water's safety for human consumption. The presence of bromide ions, organic carbon, free chlorine, and pH values were found to affect trihalomethane formation.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Said Arhzaf, Jamal Houssaini, Mohammed Naciri Bennani, Marwa Alaqarbeh, Mohammed Bouachrine
Summary: The study shows that Mg-Al hydrotalcite catalysts intercalated with acetate and carbonate anions exhibit superior catalytic activity in the aldol condensation reaction between furfural and acetone. The optimal reaction conditions are at 90 degrees C for 2 hours, achieving conversion rates of over 98% with high selectivity towards F2A for the acetate catalyst.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Uyen-Chi Nguyen Le, Ngoc Xuan Dat Mai, Kieu-Minh Le, Hoang Anh Vu, Huynh-Nhu Thi Tran, Tan Le Hoang Doan
Summary: This study aimed to enhance the bioavailability of rosmarinic acid, a bioactive compound with high anticancer activity, by encapsulating it in tetrasulfide-based porous organosilica nanoparticles. The synthesized nanoparticles were small in size and had a high surface area and an average pore diameter. The nanoparticles showed effective accumulation in cancer cells without toxicity to normal cells. Treatment with rosmarinic acid-containing nanoparticles resulted in significant cell death in cancer cells. Overall, these findings suggest that the synthesized nanoparticles can enhance the pharmacological effects of rosmarinic acid.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Jiamin Qi, Hengxi Zhu, Tianyu Yang, Xingyuan Wang, Zixuan Wang, Xiaoli Lei, Bin Li, Wenmin Qian
Summary: This study synthesized a novel iron-biochar adsorbent using the iron content in red mud to remove heavy metals from wastewater. The adsorbent showed excellent removal efficiency and sustainability. This method addresses both industrial waste recovery and heavy metal adsorption issues.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Bo Yi, Li Zhang, Haiyang Zhou
Summary: Plasma protein binding plays a crucial role in the pharmacokinetics and pharmacodynamics of therapeutic bioactive materials. In this study, the interaction of nordentatin, a member of coumarins, with human alpha-1 acid glycoprotein (AGP) was investigated, and the anticancer potency of nordentatin against human colorectal cancer cells was evaluated. The results showed that nordentatin binds to AGP through a static quenching mechanism and exhibits inhibitory effects on the growth of HCT-116 cells by increasing intracellular ROS and [Ca2+] levels and triggering apoptosis-related gene overexpression. Therefore, nordentatin could be a promising plant-based therapy for colorectal cancer.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Qiming Pang, Cui Wang, Bangtao Li, Suli Zhang, Jiaoyang Li, Shuo Gu, Xueyu Shi
Summary: This study evaluated the effects of resveratrol loaded in copolymer nanoparticles on cerebral ischemia/reperfusion (I/R) injury in rats. The results showed that RES.CP.NPs could have neuroprotective effects through their antioxidant and anti-inflammatory activities, leading to improved neurological disability scores and decreased oxidative stress levels.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Maryam Rachmawati Sumitra, Lung-Ching Chen, Wei-Chen Tsai, Muhamad Ansar, Bashir Lawal, Ntlotlang Mokgautsi, Jih-Hwa Guh, Alexander T. H. Wu, Hsu-Shan Huang
Summary: Tetraheterocyclic compounds derived from natural sources and contemporary pharmaceuticals have shown promise as multitarget therapeutic agents. In this study, a series of synthesized compounds were evaluated for their potential in breast cancer treatment. Compounds 18 and 20 demonstrated significant antiproliferative activity against breast cancer cell lines and their mode of action was revealed through molecular docking simulations.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Mohammad Khosravani, Mohsen Dehghani Ghanatghestani, Farid Moeinpour, Hossein Parvaresh
Summary: The aim of removing Pb(II) from water is to minimize the potential harm posed by toxic metals to both human health and the environment. A covalent organic framework adsorbent called TFPOTDB-SO3H was developed with excellent properties such as high repeatability, selectivity, and easy solid-liquid separation. The adsorbent showed impressive capability of adsorbing Pb(II) and effective removal of it from a solution with various ions, suggesting its potential for effectively adsorbing and removing Pb(II) heavy metal ions from wastewater.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Ashraf H. Farha, Mohamed S. Shams, Hasna A. Alali, Zakia H. Alhashem, Shehab A. Mansour, Shrouq H. Aleithan, Ragab A. Elsad
Summary: The current study examines the dielectric and thermal properties of transformer oil incorporated with Mn0.5 Zn0.5 Fe2O4 nanoparticles. The results show that the addition of Mn-Zn ferrite NPs improves the dielectric constant, dissipation factor, AC breakdown voltage, and convective heat transfer of the nanofluid.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Limin Hou, Zongpei Jiang, Minqi Ye, Xueyan Sun, Kexin Liu, Yifan Zhu, Xiaoyu Wang, Liangzhu Chen, Ruiheng Gu, Binghu Fang
Summary: The excessive accumulation of antibiotic residue in animal-derived foods poses a threat to health. Therefore, it is necessary to establish a rapid, simple, effective, safe, and highly sensitive method for detecting lincomycin residues. By using a pre-column derivatization method on high-performance liquid chromatography equipped with ultraviolet, the UV absorption of lincomycin is improved, allowing for detection and quantification.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Kun Tang, Xin-Xin Wang, Jin-Jin Zhao, Ning Ren, Jian-Jun Zhang
Summary: This study reports the synthesis, crystal structures, and thermal degradation properties of three new rare earth coordination compounds. Compounds 1-3 exhibit binuclear structures which can form chain-like structures via hydrogen bonding. Compound 2 shows potential application value in the orange-red luminescence region.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Seoyoun Yang, Eunbi Yu, See-Hyoung Park, Sae Woong Oh, Kitae Kwon, Su Bin Han, Soo Hyun Kang, Jung Hyun Lee, Heejun Ha, Minkyung Song, Jae Youl Cho, Jongsung Lee
Summary: This study investigated the effects of blue light on the hypodermis and found that it has antiadipogenic properties by reducing lipid accumulation and downregulating the expression of adipogenic genes. Blue light also increased the phosphorylation of PPAR gamma and TRPV1, suggesting its anti-adipogenic effect through these signaling pathways.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Abdul Nasir, Abdul Waheed Khan, Hamid Rafiq Khattak, Abdus Samad, Sami Ullah, Haroon Khan, Muhammad Faheem, Qian Bai
Summary: This study evaluated the effects of isoxazolone derivatives on cisplatin-induced neuropathy in a rat model. The results showed that isoxazolone derivatives effectively reversed mechanical allodynia, similar to the known therapeutic agent pregabalin. Molecular docking analysis indicated that isoxazolone derivatives have strong binding affinity for relevant receptors and potential inhibitory activity against relevant signaling pathways. This study has innovative implications for the treatment of cisplatin-induced neuropathic pain.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Shahid Wahab, Haroon Muhammad Ali, Maham Khan, Tariq Khan, Chandran Krishnaraj, Soon-Il Yun
Summary: In this study, we synthesized chitosan nanoparticles, silver nanoparticles, and chitosan/silver nanocomposites using aqueous ginger extract as a green approach. These nanomaterials showed significant antibacterial properties and low toxicity. Furthermore, the nanomaterials conjugated with tobramycin demonstrated enhanced antibacterial efficacy and exhibited interactions with Pseudomonas aeruginosa.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
