TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activation
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Title
TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activation
Authors
Keywords
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Journal
Nature Communications
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-08-11
DOI
10.1038/s41467-020-17802-4
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Note: Only part of the references are listed.- TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy through regulation of lysosomal calcium
- (2020) Hyun-Kyoung Kim et al. Autophagy
- GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis
- (2019) Zefang Tang et al. NUCLEIC ACIDS RESEARCH
- Expression of TMBIM6 in Cancers: The Involvement of Sp1 and PKC
- (2019) Raghu Patil Junjappa et al. Cancers
- Ixeris dentata Extract Increases Salivary Secretion through the Regulation of Endoplasmic Reticulum Stress in a Diabetes-Induced Xerostomia Rat Model
- (2018) Kashi Bhattarai et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Architecture of the human mTORC2 core complex
- (2018) Edward Stuttfeld et al. eLife
- Bax inhibitor 1 is a γ-secretase–independent presenilin-binding protein
- (2018) Shenjie Wu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Amino Acid Sensing by mTORC1: Intracellular Transporters Mark the Spot
- (2016) Deborah C.I. Goberdhan et al. Cell Metabolism
- Self-assembled Micelle Interfering RNA for Effective and Safe Targeting of Dysregulated Genes in Pulmonary Fibrosis
- (2016) Pyoung Oh Yoon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Calcium channel regulator Mid1 links TORC2-mediated changes in mitochondrial respiration to autophagy
- (2016) Ariadne Vlahakis et al. JOURNAL OF CELL BIOLOGY
- mTORC2 Responds to Glutamine Catabolite Levels to Modulate the Hexosamine Biosynthesis Enzyme GFAT1
- (2016) Joseph G. Moloughney et al. MOLECULAR CELL
- Glutathione biosynthesis is a metabolic vulnerability in PI(3)K/Akt-driven breast cancer
- (2016) Evan C. Lien et al. NATURE CELL BIOLOGY
- Regulation of mTORC1 by lysosomal calcium and calmodulin
- (2016) Ruo-Jing Li et al. eLife
- Multiple amino acid sensing inputs to mTORC1
- (2015) Mitsugu Shimobayashi et al. CELL RESEARCH
- Nutrient-sensing mechanisms and pathways
- (2015) Alejo Efeyan et al. NATURE
- Novel Mechanism of Macrophage-Mediated Metastasis Revealed in a Zebrafish Model of Tumor Development
- (2014) J. Wang et al. CANCER RESEARCH
- A PCR Based Protocol for Detecting Indel Mutations Induced by TALENs and CRISPR/Cas9 in Zebrafish
- (2014) Chuan Yu et al. PLoS One
- Structural basis for a pH-sensitive calcium leak across membranes
- (2014) Y. Chang et al. SCIENCE
- mTORC2 in the center of cancer metabolic reprogramming
- (2014) Kenta Masui et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Bax Inhibitor-1-mediated Ca2+ leak is decreased by cytosolic acidosis
- (2013) Santeri Kiviluoto et al. CELL CALCIUM
- mTOR Complex 2 Controls Glycolytic Metabolism in Glioblastoma through FoxO Acetylation and Upregulation of c-Myc
- (2013) Kenta Masui et al. Cell Metabolism
- hsBAFF promotes proliferation and survival in cultured B lymphocytes via calcium signaling activation of mTOR pathway
- (2013) Zhen Ke et al. CYTOKINE
- Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis
- (2013) Pengda Liu et al. NATURE CELL BIOLOGY
- Emerging landscape of oncogenic signatures across human cancers
- (2013) Giovanni Ciriello et al. NATURE GENETICS
- mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology
- (2013) C. Betz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nutrient signaling to mTOR and cell growth
- (2013) Jenna L. Jewell et al. TRENDS IN BIOCHEMICAL SCIENCES
- mTOR Signaling in Growth Control and Disease
- (2012) Mathieu Laplante et al. CELL
- Six-transmembrane Topology for Golgi Anti-apoptotic Protein (GAAP) and Bax Inhibitor 1 (BI-1) Provides Model for the Transmembrane Bax Inhibitor-containing Motif (TMBIM) Family
- (2012) Guia Carrara et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Metabolic Stress Controls mTORC1 Lysosomal Localization and Dimerization by Regulating the TTT-RUVBL1/2 Complex
- (2012) Sang Gyun Kim et al. MOLECULAR CELL
- Endoplasmic reticulum is a main localization site of mTORC2
- (2011) Delphine R. Boulbés et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Activation of mTORC2 by Association with the Ribosome
- (2011) Vittoria Zinzalla et al. CELL
- The C Terminus of Bax Inhibitor-1 Forms a Ca2+-permeable Channel Pore
- (2011) Geert Bultynck et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Enhanced Lysosomal Activity Is Involved in Bax Inhibitor-1-induced Regulation of the Endoplasmic Reticulum (ER) Stress Response and Cell Death against ER Stress
- (2011) Geum-Hwa Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of mTOR Kinase by AZD8055 Can Antagonize Chemotherapy-induced Cell Death through Autophagy Induction and Down-regulation of p62/Sequestosome 1
- (2011) Shengbing Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Improved Elution Conditions for Native Co-Immunoprecipitation
- (2011) Robin Antrobus et al. PLoS One
- mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide
- (2010) Won Jun Oh et al. EMBO JOURNAL
- Rictor Forms a Complex with Cullin-1 to Promote SGK1 Ubiquitination and Destruction
- (2010) Daming Gao et al. MOLECULAR CELL
- Hypoxia-induced metastasis model in embryonic zebrafish
- (2010) Pegah Rouhi et al. Nature Protocols
- mTOR: from growth signal integration to cancer, diabetes and ageing
- (2010) Roberto Zoncu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- BAX inhibitor-1 enhances cancer metastasis by altering glucose metabolism and activating the sodium-hydrogen exchanger: the alteration of mitochondrial function
- (2010) G-H Lee et al. ONCOGENE
- mTOR Complex 2 Is Required for the Development of Prostate Cancer Induced by Pten Loss in Mice
- (2009) David A. Guertin et al. CANCER CELL
- DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival
- (2009) Timothy R. Peterson et al. CELL
- An Emerging Role of mTOR in Lipid Biosynthesis
- (2009) Mathieu Laplante et al. CURRENT BIOLOGY
- mTOR signaling at a glance
- (2009) M. Laplante et al. JOURNAL OF CELL SCIENCE
- Bax inhibitor-1 mediates apoptosis-resistance in human nasopharyngeal carcinoma cells
- (2009) Meihong Zhang et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Hypoxia-induced pathological angiogenesis mediates tumor cell dissemination, invasion, and metastasis in a zebrafish tumor model
- (2009) S. L. C. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)
- (2008) Juan M. García-Martínez et al. BIOCHEMICAL JOURNAL
- Protein kinase Cδ expression in breast cancer as measured by real-time PCR, western blotting and ELISA
- (2008) E McKiernan et al. BRITISH JOURNAL OF CANCER
- Comparative genomics and function analysis on BI1 family
- (2008) Jinhua Zhou et al. COMPUTATIONAL BIOLOGY AND CHEMISTRY
- Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling
- (2008) Tsuneo Ikenoue et al. EMBO JOURNAL
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