Article
Chemistry, Multidisciplinary
Xiaofei Zhao, Li Jun Lim, Shun Sheng Ang, Zhi-Kuang Tan
Summary: Short-wave infrared (SWIR) light emission is important for various modern applications. However, there are limited semiconductors that can efficiently emit SWIR light. This study presents a highly efficient SWIR LED based on heavy-metal-free indium arsenide (InAs) core-shell colloidal quantum dots (CQDs), achieving high external quantum efficiencies through the implementation of a poly(vinylcarbazole) layer.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Wasim J. Mir, Tariq Sheikh, Saidkhodzha Nematulloev, Partha Maity, Khursand E. Yorov, Abdul-Hamid Emwas, Mohamed Nejib Hedhili, Mudeha Shafat Khan, Mutalifu Abulikemu, Omar F. Mohammed, Osman M. Bakr
Summary: This study reports a method for synthesizing high-quality and size-tunable InSb CQDs using commercially available precursors and under standard colloidal synthesis conditions. By changing the surface ligands of the CQDs, an increase in excited-state lifetime, efficient carrier multiplication, and slower carrier annihilation are observed. This work overcomes a major challenge in synthesizing high-quality InSb CQDs and opens up new possibilities for Pb- and Hg-free CQDs in SWIR applications.
Article
Nanoscience & Nanotechnology
Ge Mu, Tianyu Rao, Shuo Zhang, Chong Wen, Menglu Chen, Qun Hao, Xin Tang
Summary: This study reports colloidal quantum-dot upconverters with unprecedented performance, achieving a wider range of operation spectral and higher efficiency through optimization of device structure.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Review
Chemistry, Multidisciplinary
Lu-Lu Chen, Liang Zhao, Zhi-Gang Wang, Shu-Lin Liu, Dai-Wen Pang
Summary: NIR-II imaging breakthrough imaging limitations in deep tissues, while NIR-II quantum dots exhibit excellent optical properties and have become promising fluorescent biomarkers in in vivo fluorescence imaging.
Article
Chemistry, Multidisciplinary
Qiaoqiao Ci, Yuanyuan Wang, Ben Wu, Emerson Coy, Jiao Jiao Li, Daoyong Jiang, Pengfei Zhang, Guocheng Wang
Summary: Most existing carbon dots emit in the visible/first near-infrared region, limiting their penetration depth in vivo. This study presents the development of Fe-doped carbon dots with NIR-II emission and high quantum yield, demonstrating their potential as effective probes for in vivo bioimaging in the NIR-II region.
Article
Chemistry, Multidisciplinary
Vladimir Pejovic, Epimitheas Georgitzikis, Itai Lieberman, Pawel E. Malinowski, Paul Heremans, David Cheyns
Summary: Colloidal quantum dot (CQD) infrared image sensors are a cost-effective and high-performance multispectral imaging technology. By engineering the surface of CQDs, these image sensors enable sensing in two spectral channels through the fabrication of two oppositely facing pn junctions. Additionally, the design of an optical cavity reduces spectral crosstalk between the two channels.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Dongsun Muhammad, Dongsun Choi, Darshan H. Parmar, Benjamin Rehl, Yangning Zhang, Ozan Atan, Gahyeon Kim, Pan Xia, Joao M. Pina, Mengsha Li, Yanjiang Liu, Oleksandr Voznyy, Sjoerd Hoogland, Edward H. Sargent
Summary: In this study, the synthesis challenges of InSb colloidal quantum dots (CQDs) were investigated and it was found that uncontrolled reduction of the antimony precursor hinders the controlled growth of CQDs. A synthetic strategy combining nonpyrophoric precursors with zinc halide additives was developed to overcome this challenge. Experimental and computational studies showed that zinc halide additives decelerate the reduction of the antimony precursor, facilitating the growth of more uniformly sized CQDs. The choice of halide also provided additional control over this effect.
ADVANCED MATERIALS
(2023)
Article
Engineering, Electrical & Electronic
Vladimir Pejovic, Jiwon Lee, Epimitheas Georgitzikis, Yunlong Li, Joo Hyoung Kim, Itai Lieberman, Pawel E. Malinowski, Paul Heremans, David Cheyns
Summary: The letter introduces a small pixel pitch image sensor optimized for high external quantum efficiency in SWIR, utilizing PbS CQD thin films in CMOS readout arrays to achieve high-pixel density SWIR image sensors. By optimizing the photodiode stack and co-integration process, the prototype image sensor demonstrates less than 5% linearity error and 40% external quantum efficiency in SWIR, enabling acquisition of high-quality images.
IEEE ELECTRON DEVICE LETTERS
(2021)
Review
Materials Science, Multidisciplinary
Zhixu Wu, Yingdong Ou, Mengqiang Cai, Yuhao Wang, Rongxin Tang, Yong Xia
Summary: Lead chalcogenide quantum dots are the next generation of ideal narrow bandgap infrared semiconductors due to their solution processing, low-cost fabrication, size-tunable infrared bandgap, and excellent optoelectronic properties. Recent advances in synthesis methods, surface ligand engineering, and device architecture engineering have greatly improved the performance of photodetectors based on these quantum dots. With the rapid development of consumer electronics, there is a growing demand for short-wave infrared (SWIR) imaging sensors. QD-based imaging technologies, which can reduce the cost of SWIR imaging sensors and promote their commercial application in consumer electronics, have been studied extensively. This article summarizes the recent advances in QD-based photodetectors and imaging sensors, focusing on QD synthesis, surface ligand engineering, device architecture engineering, and imaging technology.
ADVANCED OPTICAL MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Ching-Wei Lin, Shengnan Huang, Marco Colangelo, Changchen Chen, Franco N. C. Wong, Yanpu He, Karl K. Berggren, Angela M. Belcher
Summary: In this study, gold nanorods were used to enhance short-wave infrared upconversion fluorescence for in vivo imaging. The upconversion emission showed significantly higher signal contrast than downconversion emission in a nonscattering medium. By varying the excitation power, the intensity of the upconversion emission was found to depend linearly on the power, suggesting an unchanged emission mechanism.
Article
Chemistry, Multidisciplinary
Nima Taghipour, Guy L. Whitworth, Andreas Othonos, Mariona Dalmases, Santanu Pradhan, Yongjie Wang, Gaurav Kumar, Gerasimos Konstantatos
Summary: A binary blend of CQDs and ZnO nanocrystals is used to passivate trap states in PbS-CQD gain medium, leading to improved Auger lifetime and suppression of trap-assisted Auger recombination. Integration of this binary blend with a DFB resonator has demonstrated stable single-mode lasing emission with low threshold and continuous operation of 5 hours under room temperature and ambient conditions.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Jari Leemans, Vladimir Pejovic, Epimitheas Georgitzikis, Matthias Minjauw, Abu Bakar Siddik, Yu-Hao Deng, Yinghuan Kuang, Gunther Roelkens, Christophe Detavernier, Itai Lieberman, Pawel E. Malinowski, David Cheyns, Zeger Hens
Summary: QD photodiodes made from non-restricted In(As,P) QDs demonstrate sensitivity for SWIR light up to 1400 nm, making them promising for applications in QD image sensors.
Article
Chemistry, Multidisciplinary
Yuan Jiang, Haibao Shao, Hangning Xu, Jiahao Yang, Yi Wang, Haonan Xiong, Pengyao Wang, Xilin Wang
Summary: An ultrafast and facile aqueous synthetic approach for CdTe/CdS core/shell quantum dots with emission from the green to near-infrared window has been reported. The CdTe/CdS QDs with emission wavelengths at 700 and 800 nm can be obtained within 20-45 minutes under optimized conditions, and the resulting QDs are highly luminescent without postsynthesis treatment. The influences of various experimental factors on the synthesis rate and luminescent properties of the CdTe/CdS QDs have been considered.
MATERIALS TODAY CHEMISTRY
(2021)
Review
Materials Science, Multidisciplinary
Xinwei Guan, Xuechao Yu, Dharmaraj Periyanagounder, Mercy Rose Benzigar, Jing-Kai Huang, Chun-Ho Lin, Jiyun Kim, Simrjit Singh, Long Hu, Guozhen Liu, Dehui Li, Jr-Hau He, Feng Yan, Qi Jie Wang, Tom Wu
Summary: 2D materials show promise in optoelectronic applications, particularly in infrared detectors, due to their unique electronic, optical, and mechanical properties. Recent research focuses on the design and optimization of devices in the short-wave, mid-wave, and long-wave infrared regimes, discussing the impact of 2D material properties on device performance and the characteristics and challenges of heterostructures based on 2D materials.
ADVANCED OPTICAL MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Hongping Deng, Christian J. Konopka, Suma Prabhu, Suresh Sarkar, Natalia Gonzalez Medina, Muhammad Fayyaz, Opeyemi H. Arogundade, Hashni Epa Vidana Gamage, Sayyed Hamed Shahoei, Duncan Nall, Yeoan Youn, Iwona T. Dobrucka, Christopher O. Audu, Amrita Joshi, William J. Melvin, Katherine A. Gallagher, Paul R. Selvin, Erik R. Nelson, Lawrence W. Dobrucki, Kelly S. Swanson, Andrew M. Smith
Summary: This study presents fluorescent and radioisotopic quantum dots (QDs) for multimodal imaging of macrophage cells. These dextran-mimetic QDs exhibit enhanced optical quantification, long-term photostability, and resistance to chemical fixation compared to other probes.
Article
Chemistry, Multidisciplinary
Christian Paul Bold, Daniel Lucena-Agell, Maria Angela Oliva, Jose Fernando Diaz, Karl-Heinz Altmann
Summary: This study describes a new method for the total synthesis of the macrodiolide C(13)/C(13 ')-bis(desmethyl)disorazole Z, and demonstrates its binding to tubulin and inhibition of tubulin assembly, indicating a stronger cell growth inhibitory effect.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Ahmed Refaat, Blanca del Rosal, Viktoria Bongcaron, Aidan P. G. Walsh, Geoffrey Pietersz, Karlheinz Peter, Simon E. Moulton, Xiaowei Wang
Summary: Acute thrombosis is a significant cause of death and illness globally. Researchers have discovered that targeted photothermal therapy using liposomes can effectively dissolve blood clots without major side effects. Liposomes targeted to activated platelets can selectively accumulate in thrombi, leading to enhanced treatment efficacy.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Tobias M. Bruetsch, Etienne Cotter, Daniel Lucena-Agell, Mariano Redondo-Horcajo, Carolina Davies, Bernhard Pfeiffer, Sandro Pagani, Simone Berardozzi, J. Fernando Diaz, John H. Miller, Karl-Heinz Altmann
Summary: In this study, five analogs of (-)-zampanolide (ZMP) were synthesized and their biochemical and cellular properties were evaluated. These analogs were derived from 13-desmethylene-(-)-zampanolide (DM-ZMP), which is as potent as ZMP in inhibiting cancer cell growth. Key steps in the synthesis of all compounds included the formation of a dioxabicyclo[15.3.1]heneicosane core and the establishment of the C(20) stereocenter. All modifications resulted in reduced cellular activity and microtubule-binding affinity compared to DM-ZMP, with varying degrees. The most potent analog, 2,3-dihydro-13-desmethylene zampanolide, showed cellular potency within a ninefold range of DM-ZMP.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Biology
Andrea E. Prota, Daniel Lucena-Agell, Yuntao Ma, Juan Estevez-Gallego, Shuo Li, Katja Bargsten, Fernando Josa-Prado, Karl-Heinz Altmann, Natacha Gaillard, Shinji Kamimura, Tobias Muhlethaler, Federico Gago, Maria A. Oliva, Michel O. Steinmetz, Wei-Shuo Fang, J. Fernando Diaz
Summary: This study provides atomic-level details of the interaction between paclitaxel and tubulin, shedding light on the mechanism of action and binding determinants.
Article
Materials Science, Multidisciplinary
Adilet Zhakeyev, Mansour Abdulrhman, Yuqi Zhang, Feng Li, Guanying Chen, Jose Marques-Hueso
Summary: In this work, a technique for multi-material stereolithography is presented, which overcomes the limitation of layer-by-layer deposition. Selective volumetric crosslinking is achieved by using invisibility windows and upconversion, allowing for printing inside and through previously 3D printed parts. This technique opens up numerous possibilities, such as printing objects inside cavities in a different material, restoration of broken objects and artifacts, 3D circuitry, and in-situ bioprinting.
APPLIED MATERIALS TODAY
(2023)
Article
Chemistry, Multidisciplinary
Liyan Ming, Irene Zabala-Gutierrez, Paloma Rodriguez-Sevilla, Jorge Rubio Retama, Daniel Jaque, Riccardo Marin, Erving Ximendes
Summary: This article introduces a luminescence lifetime estimation method based on U-NET to improve the estimation accuracy under extremely low signal-to-noise ratio conditions. The effectiveness of U-NET is demonstrated in luminescence lifetime thermometry and its sensing performance improvement is verified through two experiments under extreme measurement conditions.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Carlos D. S. Brites, Riccardo Marin, Markus Suta, Albano N. Carneiro Neto, Erving Ximendes, Daniel Jaque, Luis D. Carlos
Summary: Luminescence (nano)thermometry is a remote sensing technique that utilizes the temperature dependency of luminescence features to measure temperature. It has potential applications in various fields and requires the establishment of a theoretical background, standardized practices, and improved readouts through multiparametric analysis and artificial intelligence algorithms. Challenges in luminescence thermometry and the need for continuous innovation are also discussed.
ADVANCED MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Adilet Zhakeyev, Fenella Walker, Mansour Abdulrhman, Jose Marques-Hueso
Summary: This study demonstrates the synergistic effect of silver ions to enhance the crosslinking of 3D printing photo polymers, enabling selective metallization of multi-material parts. By incorporating a ytterbium-thulium co-doped sodium yttrium fluoride phosphor into a photopolymer resin, voxel crosslinking in the centimeter scale depth is achieved using a low-cost NIR laser. The addition of Ag(I) ions enables faster curing speeds and the subsequent copper plating allows integration of metalized parts on different substrates.
Editorial Material
Materials Science, Multidisciplinary
Jorge Mendez-Ramos, Luis D. Carlos, Fiorenzo Vetrone, Jose Marques-Hueso, Nazario Martin
Article
Chemistry, Multidisciplinary
Mansour Abdulrhman, Adarsh Kaniyoor, Carmen M. Fernandez-Posada, Pablo Acosta-Mora, Ian McLean, Nick Weston, Marc P. Y. Desmulliez, Jose Marques-Hueso
Summary: The direct laser writing process allows for copper micro-track production on specific polymers; however, certain important 3D printing polymers, like ABS and acrylates, are unable to undergo this treatment. This study presents a method for producing copper microcircuitry on 3D substrates made of these materials by utilizing direct laser writing with a low-power diode laser. The technique involves coating a thin layer of polyimide on a 3D-printed structure, followed by chemical treatments and low-power laser-induced photoreduction.
NANOSCALE ADVANCES
(2023)
Article
Chemistry, Multidisciplinary
Ana C. C. Soares, Tasso O. Sales, Erving C. Ximendes, Daniel Jaque, Carlos Jacinto
Summary: In recent years, there has been significant interest in infrared emitting luminescent nanothermometers due to their potential for new diagnosis and therapy procedures. However, concerns have been raised regarding their reliability, as tissues can induce spectral distortions even in the commonly used second biological window. In this study, the effectiveness of shifting the operation range of these nanothermometers to the third biological window is demonstrated, showing minimal distortion by tissue and opening the path to reliable luminescence thermometry. Advanced analysis of emission spectra allows for sub-degree thermal uncertainties.
NANOSCALE ADVANCES
(2023)
Article
Chemistry, Multidisciplinary
Dominic Taylor, Thomas Malcomson, Adilet Zhakeyev, Georgina M. Rosair, Martin J. Paterson, Jose Marques-Hueso, Scott J. Dalgarno, Filipe Vilela
Summary: Regioselective stepwise phenylation of 4,7-diarylbenzo[c][1,2,5]thiadiazole fluorophores was achieved by a facile one-pot, three-step synthetic strategy involving sequential borylation, hydroxydechlorination, and Suzuki-Miyaura cross-coupling reactions. Selectivity was achieved by using BCl3 to install a boronic acid group in the ortho-position of only one of the diaryl groups. The introduction of ortho-phenyl groups through Suzuki-Miyaura cross-coupling resulted in twisted structures with hindered intramolecular rotation, allowing for adjustment of the fluorophore absorption and emission properties.
Article
Biochemical Research Methods
Jose Lifante, Alvaro Moreno-Ruperez, Erving Ximendes, Riccardo Marin, Teresa Priego, Asuncion Lopez-Calderon, Ana Isabel Martin, Maria Paz Nieto-Bona, Elena Nebot, Gines Lifante-Pedrola, Daniel Jaque, Luis Monge, Nuria Fernandez, Miriam Granado
Summary: In this study, the combination of transient thermometry and infrared-emitting nanothermometers was successfully used for early detection of muscle atrophy after denervation. Experimental results indicate that the changes in muscle thermal dynamics at the onset of muscle atrophy are caused by the disruption of the peripheral nervous autonomous system. This work demonstrates the potential of infrared luminescence thermometry for early diagnosis of diseases of the nervous system.
JOURNAL OF BIOPHOTONICS
(2023)
Article
Chemistry, Multidisciplinary
Marina Paris Ogayar, Diego Mendez-Gonzalez, Irene Zabala Gutierrez, Alvaro Artiga, Jorge Rubio-Retama, Oscar G. Calderon, Sonia Melle, Aida Serrano, Ana Espinosa, Daniel Jaque, Riccardo Marin
Summary: Luminescence nanothermometry is a technique that uses luminescence signals from nanosized materials to remotely and minimally invasively measure temperature. However, in a biomedical context, the reliability of temperature measurement is compromised by bias caused by environmental conditions. This study reveals an unexpected source of bias induced by metal ions, which enhances the emission of Ag2S nanothermometers. These findings highlight the need for caution when using luminescence nanothermometry in complex biological environments.