Genetic risk factors for venous thromboembolism

Identification of key biomolecules in rheumatoid arthritis through the reconstruction of comprehensive disease-specific biological networks

(2020) Betul Comertpay et al.   AUTOIMMUNITY

Rivaroxaban in Peripheral Artery Disease after Revascularization

(2020) Marc P. Bonaca et al.   NEW ENGLAND JOURNAL OF MEDICINE

PCSK9 in Haemostasis and Thrombosis: Possible Pleiotropic Effects of PCSK9 Inhibitors in Cardiovascular Prevention

(2019) Francesco Paciullo et al.   THROMBOSIS AND HAEMOSTASIS

Thrombophilia, risk factors and prevention

(2019) Elena Campello et al.   Expert Review of Hematology

Opportunities and challenges for transcriptome-wide association studies

(2019) Michael Wainberg et al.   NATURE GENETICS

Choosing a Mouse Model of Venous Thrombosis

(2019) Jose A. Diaz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Benefits and limitations of genome-wide association studies

(2019) Vivian Tam et al.   NATURE REVIEWS GENETICS

Genome-wide association study of peripheral artery disease in the Million Veteran Program

(2019) Derek Klarin et al.   NATURE MEDICINE

Next-Generation Sequencing of 17 Genes Associated with Venous Thromboembolism Reveals a Deficit of Non-Synonymous Variants in Procoagulant Genes

(2019) Eric Manderstedt et al.   THROMBOSIS AND HAEMOSTASIS

Genomic and Transcriptomic Association Studies Identify 16 Novel Susceptibility Loci for Venous Thromboembolism

(2019) Sara Lindstrom et al.   BLOOD

2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS)

(2019) Stavros V Konstantinides et al.   EUROPEAN HEART JOURNAL

Genetics of venous thromboembolism revised

(2019) Bengt Zöller   BLOOD

Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease

(2019) Derek Klarin et al.   NATURE GENETICS

Allele-selective RUNX1 binding regulates P1 blood group status by transcriptional control ofA4GALT

(2018) Julia S. Westman et al.   BLOOD

Rivaroxaban with or without aspirin in patients with stable coronary artery disease: an international, randomised, double-blind, placebo-controlled trial

(2018) Stuart J Connolly et al.   LANCET

GeneMANIA update 2018

(2018) Max Franz et al.   NUCLEIC ACIDS RESEARCH

Identification of nine novel loci related to hematological traits in a Japanese population

(2018) Yoshiki Yasukochi et al.   PHYSIOLOGICAL GENOMICS

Targeted sequencing to identify novel genetic risk factors for deep vein thrombosis: a study of 734 genes

(2018) H.G. de Haan et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Quantitative Analysis of Human Red Blood Cell Proteome

(2017) Agata H. Bryk et al.   JOURNAL OF PROTEOME RESEARCH

Whole exome sequencing in thrombophilic pedigrees to identify genetic risk factors for venous thromboembolism

(2017) Marisa L. R. Cunha et al.   PLoS One

Identification of unique venous thromboembolism-susceptibility variants in African-Americans

(2017) Sebastian Armasu et al.   THROMBOSIS AND HAEMOSTASIS

A sibling based design to quantify genetic and shared environmental effects of venous thromboembolism in Sweden

(2017) Bengt Zöller et al.   THROMBOSIS RESEARCH

Whole Exome Sequencing Reveals Severe Thrombophilia in Acute Unprovoked Idiopathic Fatal Pulmonary Embolism

(2017) Matt Halvorsen et al.   EBioMedicine

Economic Evaluations of Thrombophilia Screening Prior to Prescribing Combined Oral Contraceptives: A Systematic and Critical Review

(2017) Erin Vernon et al.   Applied Health Economics and Health Policy

Lifetime Risk of Venous Thromboembolism in Two Cohort Studies

(2016) Elizabeth J. Bell et al.   AMERICAN JOURNAL OF MEDICINE

New Prothrombin Mutation (Arg596Trp, Prothrombin Padua 2) Associated With Venous ThromboembolismSignificance

(2016) Cristiana Bulato et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Rare genetic variants in SMAP1, B3GAT2, and RIMS1 contribute to pediatric venous thromboembolism

(2016) Frank Rühle et al.   BLOOD

Combined oral contraceptives, thrombophilia and the risk of venous thromboembolism: a systematic review and meta-analysis

(2016) E. F. W. van Vlijmen et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Identification and functional characterization of a novel F5 mutation (Ala512Val, FVB onn ) associated with activated protein C resistance

(2016) B. Pezeshkpoor et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Next-Generation Sequencing and In Vitro Expression Study of ADAMTS13 Single Nucleotide Variants in Deep Vein Thrombosis

(2016) Maria Teresa Pagliari et al.   PLoS One

Epidemiology of Familial Aggregation of Venous Thromboembolism

(2016) Xinjun Li et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Diagnosis and management of factor V Leiden

(2016) Elena Campello et al.   Expert Review of Hematology

Three novel variants in the coagulation factor V gene associated with deep venous thrombosis in Chilean patients with Amerindian ethnic background

(2015) Neftalí Guzmán et al.   CLINICA CHIMICA ACTA

Epidemiology of venous thromboembolism

(2015) John A. Heit   Nature Reviews Cardiology

Introduction to the analysis of next generation sequencing data and its application to venous thromboembolism

(2015) Joost C. M. Meijers et al.   THROMBOSIS AND HAEMOSTASIS

Family history of venous thromboembolism as a risk factor and genetic research tool

(2015) Xinjun Li et al.   THROMBOSIS AND HAEMOSTASIS

Classic thrombophilic gene variants

(2015) Massimo Franchini et al.   THROMBOSIS AND HAEMOSTASIS

Novel FV mutation (W1920R, FVNara) associated with serious deep vein thrombosis and more potent APC resistance relative to FVLeiden

(2014) K. Nogami et al.   BLOOD

Serum complement C4b, fibronectin, and prolidase are associated with the pathological changes of pulmonary tuberculosis

(2014) Chong Wang et al.   BMC INFECTIOUS DISEASES

Next-generation sequencing study finds an excess of rare, coding single-nucleotide variants ofADAMTS13in patients with deep vein thrombosis

(2013) L. A. Lotta et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A novel prothrombin mutation in two families with prominent thrombophilia- the first cases of antithrombin resistance in a Caucasian population

(2013) Valentina Djordjevic et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Red cell distribution width and risk for venous thromboembolism: A population-based cohort study

(2013) Bengt Zöller et al.   THROMBOSIS RESEARCH

Venous thromboembolism: Epidemiology and magnitude of the problem

(2012) Samuel Z. Goldhaber   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

The endothelial protein C receptor (PROCR) Ser219Gly variant and risk of common thrombotic disorders: a HuGE review and meta-analysis of evidence from observational studies

(2012) J. Dennis et al.   BLOOD

Molecular defect of ‘Prothrombin Amrita’: Substitution of arginine by glutamine (Arg553 to Gln) near the Na+ binding loop of prothrombin

(2012) Sajini Sivasundar et al.   BLOOD CELLS MOLECULES AND DISEASES

Identification of genetic risk variants for deep vein thrombosis by multiplexed next-generation sequencing of 186 hemostatic/pro-inflammatory genes

(2012) Luca A Lotta et al.   BMC Medical Genomics

Thrombosis from a Prothrombin Mutation Conveying Antithrombin Resistance

(2012) Yuhri Miyawaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Apixaban for Extended Treatment of Venous Thromboembolism

(2012) Giancarlo Agnelli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epidemiology of recurrent venous thrombosis

(2011) D.D. Ribeiro et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Risk of pulmonary embolism in patients with autoimmune disorders: a nationwide follow-up study from Sweden

(2011) Bengt Zöller et al.   LANCET

Unusual Site Thrombosis

(2011) Marco P. Donadini et al.   SEMINARS IN HEMATOLOGY

C4BPB/C4BPA is a new susceptibility locus for venous thrombosis with unknown protein S-independent mechanism: results from genome-wide association and gene expression analyses followed by case-control studies

(2010) A. Buil et al.   BLOOD

Thrombotic risk factors: Basic pathophysiology

(2010) Ida Martinelli et al.   CRITICAL CARE MEDICINE

A Novel Mutation (G2172→C) in the Factor V Gene in a Chinese Family with Hereditary Activated Protein C Resistance

(2010) Huacong Cai et al.   THROMBOSIS RESEARCH

Common susceptibility alleles are unlikely to contribute as strongly as the FV and ABO loci to VTE risk: results from a GWAS approach

(2009) D.-A. Tregouet et al.   BLOOD

Genetics of venous thrombosis

(2009) F. R. ROSENDAAL et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

X-Linked Thrombophilia with a Mutant Factor IX (Factor IX Padua)

(2009) Paolo Simioni et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fibrin network structure and clot mechanical properties are altered by incorporation of erythrocytes

(2009) Kathryn Gersh et al.   THROMBOSIS AND HAEMOSTASIS