4.2 Article

Parotitis due toBurkholderia cepaciainfection after autologous hematopoietic stem cell transplantation

Journal

TRANSPLANT INFECTIOUS DISEASE
Volume 22, Issue 6, Pages -

Publisher

WILEY
DOI: 10.1111/tid.13374

Keywords

autologous hematopoietic stem cell transplantation; Burkholderia cepacia; infection; parotitis; T-cell lymphoblastic lymphoma

Funding

  1. project of Anhui Province's key research and development [201904a07020036]

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Burkholderia cepaciapredominantly causes opportunistic infections in hospitalized and immunocompromised patients such as patients with cystic fibrosis, cancer, or human immunodeficiency virus (HIV). Nonetheless,Burkholderia cepaciais infrequently reported to cause infection in hematopoietic stem cell transplantation (HSCT) recipients. Herein, we report a rare case of suppurative parotitis in a 31-year-old patient with T-cell lymphoblastic lymphoma (T-LBL) who underwent auto-HSCT. The secretion from the Stensen duct was collected, andBurkholderia cepaciawas detected using the VITEK-2 identification system. Additionally, sensitive antibiotic therapy against this bacterium was also effective. This is the first case of parotitis triggered byBurkholderia cepaciaafter auto-HSCT, and it is also the first reported domestic case. This case emphasizes the importance of considering bacterial infections in general andBurkholderia cepaciaspecifically in HSCT patients with post-transplant parotitis.

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