4.4 Article

Scandium-catalyzed Michael addition of quinazolinones and vinylazaarenes

Journal

TETRAHEDRON LETTERS
Volume 61, Issue 23, Pages -

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2020.151926

Keywords

Quinazolinones; Scandium; Vinylazaarenes; Michael addition

Funding

  1. Natural Science Foundation of Hebei Province of China [B2019208137]

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We described a novel scandium-catalyzed selective Michael addition of quinazolinones and vinylazaarenes. The protocol proceeds smoothly to give diverse quinazolinone derivatives in moderate to excellent yields. The high practicality of this protocol was proved by excellent chemo selectivity and broad substrate and functional group compatibility. (C) 2020 Elsevier Ltd. All rights reserved.

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