Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities

Genetic variation in PLEKHG1 is associated with white matter hyperintensities (n = 11,226)

(2019) Matthew Traylor et al.   NEUROLOGY

NOS3 Inhibition Confers Post-Ischemic Protection to Young and Aging White Matter Integrity by Conserving Mitochondrial Dynamics and Miro-2 Levels

(2018) Chinthasagar Bastian et al.   JOURNAL OF NEUROSCIENCE

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

(2018) Rainer Malik et al.   NATURE GENETICS

Classification and characterization of periventricular and deep white matter hyperintensities on MRI: A study in older adults

(2018) Ludovica Griffanti et al.   NEUROIMAGE

Genetic Study of White Matter Integrity in UK Biobank (N=8448) and the Overlap With Stroke, Depression, and Dementia

(2018) Loes C.A. Rutten-Jacobs et al.   STROKE

Exome Chip Analysis Identifies Low-Frequency and Rare Variants inMRPL38for White Matter Hyperintensities on Brain Magnetic Resonance Imaging

(2018) Xueqiu Jian et al.   STROKE

Genome-wide meta-analysis identifies 3 novel loci associated with stroke

(2018) Rainer Malik et al.   ANNALS OF NEUROLOGY

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

(2017) Philipp S. Wild et al.   JOURNAL OF CLINICAL INVESTIGATION

The “Kelch” Surprise: KLHL24, a New Player in the Pathogenesis of Skin Fragility

(2017) Cristina Has   JOURNAL OF INVESTIGATIVE DERMATOLOGY

COL4A2 is associated with lacunar ischemic stroke and deep ICH

(2017) Kristiina Rannikmäe et al.   NEUROLOGY

Impact of interaction between the G870A and EFEMP1 gene polymorphism on glioma risk in Chinese Han population

(2017) Libin Yang et al.   Oncotarget

Blood pressure gradients in cerebral arteries: a clue to pathogenesis of cerebral small vessel disease

(2017) Pablo J Blanco et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Genetic discovery in multi-ethnic populations

(2016) Matthew Traylor et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Detection and interpretation of shared genetic influences on 42 human traits

(2016) Joseph K Pickrell et al.   NATURE GENETICS

White matter disease in midlife is heritable, related to hypertension, and shares some genetic influence with systolic blood pressure

(2016) Christine Fennema-Notestine et al.   NeuroImage-Clinical

Multiethnic Genome-Wide Association Study of Cerebral White Matter Hyperintensities on MRICLINICAL PERSPECTIVE

(2015) Benjamin F.J. Verhaaren et al.   Circulation-Cardiovascular Genetics

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke

(2015) Matthew Traylor et al.   NEUROLOGY

Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease

(2015) K. Rannikmae et al.   NEUROLOGY

Multiethnic Genome-Wide Association Study of Cerebral White Matter Hyperintensities on MRICLINICAL PERSPECTIVE

(2015) Benjamin F.J. Verhaaren et al.   Circulation-Cardiovascular Genetics

White matter microstructure pathology in classic galactosemia revealed by neurite orientation dispersion and density imaging

(2014) Inge Timmers et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Deterioration of Gait and Balance over Time: The Effects of Age-Related White Matter Change - The LADIS Study

(2013) Stefan H. Kreisel et al.   CEREBROVASCULAR DISEASES

Chemical chaperone treatment reduces intracellular accumulation of mutant collagen IV and ameliorates the cellular phenotype of a COL4A2 mutation that causes haemorrhagic stroke

(2013) Lydia S. Murray et al.   HUMAN MOLECULAR GENETICS

Enlarged Perivascular Spaces and Cerebral Small Vessel Disease

(2013) Gillian M. Potter et al.   International Journal of Stroke

Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging

(2013) Joanna M Wardlaw et al.   LANCET NEUROLOGY

Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration

(2013) Joanna M Wardlaw et al.   LANCET NEUROLOGY

Remote ischemic preconditioning regulates HIF-1α levels, apoptosis and inflammation in heart tissue of cardiosurgical patients: a pilot experimental study

(2012) Martin Albrecht et al.   BASIC RESEARCH IN CARDIOLOGY

COL4A2 mutation associated with familial porencephaly and small-vessel disease

(2012) Elly Verbeek et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

COL4A1 and COL4A2 mutations and disease: insights into pathogenic mechanisms and potential therapeutic targets

(2012) D. S. Kuo et al.   HUMAN MOLECULAR GENETICS

COL4A2 Mutations Impair COL4A1 and COL4A2 Secretion and Cause Hemorrhagic Stroke

(2011) Marion Jeanne et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-wide association studies of cerebral white matter lesion burden

(2011) Myriam Fornage et al.   ANNALS OF NEUROLOGY

Replication Study of Chr17q25 With Cerebral White Matter Lesion Volume

(2011) Benjamin F.J. Verhaaren et al.   STROKE

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Heterogeneity of small vessel disease: a systematic review of MRI and histopathology correlations

(2010) A. A. Gouw et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Blood Pressure and White-Matter Disease Progression in a Biethnic Cohort

(2009) Rebecca F. Gottesman et al.   STROKE

White matter hyperintensities in mid-adult life

(2008) Perminder Sachdev et al.   CURRENT OPINION IN PSYCHIATRY