Article
Multidisciplinary Sciences
Michael Volokh, Menny Shalom
Summary: In this article, the use of polymeric carbon nitride (CN) materials as light absorbers in photoelectrochemical cells for water-splitting is described. The deposition techniques and procedures for CN in the laboratory are discussed, along with the merits and shortcomings of resulting layers. The development of high photoelectrochemical water-splitting activity in photoanodes using CN as photoabsorbers is demonstrated, and the future prospects of this field are presented.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Y. Chen, M. Yang, Y. Jia, P. Yan, F. Chen, J. Qian, L. Xu, H. Li
Summary: The PEC aptasensor based on the ternary heterostructure of NiS2/NiFe LDH/g-C3N4 enables efficient and sensitive detection of residual antibiotics, showing great potential for various applications.
MATERIALS TODAY CHEMISTRY
(2022)
Article
Chemistry, Physical
Longbo Jiang, Jinjuan Yang, Xingzhong Yuan, Jiayin Guo, Jie Liang, Wangwang Tang, Yaoning Chen, Xiaodong Li, Hou Wang, Wei Chu
Summary: This review discusses the effects of vacancy defects on CN photocatalysts, highlighting the tuning of photoelectric properties and photocatalytic performance. Various characterization methods are summarized, providing a basis for further research and development in this field.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Jin Zhang, Jie Zhang, Changxue Dong, Yu Xia, Lan Jiang, Gang Wang, Ruilin Wang, Jinwei Chen
Summary: A general method is developed for synthesizing highly homogeneous and dense polymerized carbon nitride (PCN) nanosheet films directly on F: SnO2 (FTO). Detailed photoelectrochemical (PEC) water-splitting studies demonstrate that the as-synthesized PCN films exhibit outstanding performance as photoanodes for PEC water-splitting. The optimal PCN photoanode shows excellent photocurrent density, monochromatic incident photon-to-electron conversion efficiency (IPCE) values, and hole extraction efficiency, making it a new benchmark for PCN photoanode materials.
Article
Chemistry, Multidisciplinary
Tirza Shmila, Sanjit Mondal, Shmuel Barzilai, Neeta Karjule, Michael Volokh, Menny Shalom
Summary: A sodium- and boron-doped carbon nitride layer with excellent activity as a photoanode in a water-splitting photoelectrochemical cell is synthesized. The doping process results in a dense CN layer with improved charge separation and extended visible light response. The optimized photoanode exhibits state-of-the-art performance in terms of photocurrent densities, external quantum efficiencies, and onset potential.
Review
Engineering, Environmental
Jinjuan Yang, Hou Wang, Longbo Jiang, Hanbo Yu, Yanlan Zhao, Haoyun Chen, Xingzhong Yuan, Jie Liang, Hui Li, Zhibin Wu
Summary: This paper discusses the enhancement of visible light activity in polymeric carbon nitride (CN) through defect control, summarizing methods for preparing defective CN. The paper also delves into the progress of defective CN in various applications such as water oxidation, hydrogen production, CO2 reduction, etc.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Xiaochun Li, Jiawen Wang, Jiawei Xia, Yuanxing Fang, Yidong Hou, Xianzhi Fu, Menny Shalom, Xinchen Wang
Summary: Polymeric carbon nitride (PCN) is a sustainable, metal-free semiconductor that has been studied for its potential in photoelectrochemical (PEC) water splitting. However, the amorphous nature of the polymer limits the charge transfer along the films, thus affecting its performance. In this study, the researchers successfully incorporated gradient concentration of cobalt disulfide (CoS2) into PCN films, resulting in improved charge transfer and enhanced performance for PEC water oxidation.
Article
Chemistry, Physical
Feng Lin, Tong Wang, Zhujuan Ren, Xiaorong Cai, Yulin Wang, Jun Chen, Jianghao Wang, Shaohong Zang, Feifei Mao, Liang Lv
Summary: In this study, central nitrogen vacancies polymeric carbon nitride (PCN-NVC) were rationally prepared for photocatalytic H2O2 production, exhibiting a high hydrogen production rate and optimized electron-hole pair kinetics.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Engineering, Chemical
Jin Gao, Junxia Shao, Hua Li, Najun Li, Dongyun Chen, Qingfeng Xu, Jianmei Lu
Summary: The sluggish charge transfer and fast recombination of charge carriers are improved by introducing carbon vacancies and Rh2O3 nanoparticles into carbon nitride, leading to enhanced photocatalytic performance for the complete removal of Bisphenol A in 15 minutes. The modification of carbon vacancies regulates active charge carriers, excitons, and trap states, while in situ photodeposited Rh2O3 nanoparticles act as hole-transfer mediators, suppressing charge recombination. This strategy provides guidance for the design of efficient photocatalysts for phenolic wastewater remediation.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Chemistry, Physical
Lifang Sun, Wen Li, Gaojian Lv, Wei Wang, Shougang Chen
Summary: Heterogeneous catalysis composed of plasmonic metal and semiconductor has been used for tuning local surface electron density in MOA. However, there is an antagonistic effect between Schottky junction carriers and SPR induced hot carriers transfer routers, which can be mitigated by the Cu2O/Ag/V-CN photocatalytic antifoulant. This antifoulant shows a ternary Z-scheme heterojunction structure, which weakens the antagonistic effect and improves the efficiency of carriers separation. Moreover, Cu2O/Ag/V-CN exhibits enhanced O2 production capacity, efficient carriers separation, longer carriers lifetime, and reduced photocorrosion tendency.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Engineering, Environmental
Qiuchan Li, Yawen Tong, Yubin Zeng, Xiang-Kui Gu, Mingyue Ding
Summary: This article introduces the synthesis of a photocatalyst PCN using biomass-derived raw materials and adjusting vacancies and porous structures to achieve excellent visible-light photocatalytic activity, which is of great research significance.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Nanoscience & Nanotechnology
Liqun Wang, Wenping Si, Yuhang Ye, Sihui Wang, Feng Hou, Xinggang Hou, Hongkun Cai, Shi Xue Dou, Ji Liang
Summary: The TiO2 nanotube array implanted with Cu ions and decorated with polymeric carbon nitride shows significantly improved performance in photoelectrochemical water splitting, thanks to the synergistic effect of Cu-ion implantation and PCN decoration.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Physical
Wenyao Zhang, Maiwen Zhang, Wenwen Liu, Aiping Yu
Summary: A molten-based defect engineering strategy was reported to prepare nitrogen-deficient g-C3N4 quantum dots for photo-electrochemical water splitting, which can effectively improve carrier separation, facilitate charge transport dynamics, and boost hole extraction.
Article
Engineering, Environmental
Hao Zhang, Yunxiong Zeng, Xinqing Wang, Xingyu Zhan, Jingcai Xu, Ao Jin, Bo Hong
Summary: Optimizing surface atom properties by regulating electron configuration is a promising strategy to improve the separation of electron-hole pairs in carbon nitride. The study prepared sea urchin carbon nitride with C-v and O-s mediated electronic structures, which exhibited high photocatalytic activity and stability towards tetracycline. In addition, crucial factors affecting photoactivity and the photodegradation mechanism were investigated.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Xin Wang, Siqing Ma, Boyan Liu, Songcan Wang, Wei Huang
Summary: Photoelectrochemical (PEC) water splitting for hydrogen evolution is a promising technology for solving energy and environmental issues, but current PEC systems have low solar-to-hydrogen (STH) conversion efficiencies due to inefficient photoelectrode materials. The recent development of defect engineering in photoelectrodes has greatly improved PEC performance and has the potential to overcome the low STH efficiency bottleneck. This review summarizes the types and construction methods of defects in photoelectrode materials, discusses the enhancement mechanism of defect engineering in terms of light absorption, carrier separation and transport, and surface redox reactions, and presents the application prospects and challenges of defect engineering in PEC water splitting.
CHEMICAL COMMUNICATIONS
(2023)
Article
Engineering, Environmental
Lijun Ding, Jie Wei, Yu Qiu, Yuan Wang, Zuorui Wen, Jing Qian, Nan Hao, Caifeng Ding, Yaqi Li, Kun Wang
Summary: The MoTe2 NPs/RGO heterostructures demonstrate excellent photoelectric performance and show promise as visible light-responsive materials for PEC biosensors. The label-free PEC aptasensor based on this material has a wide linear range and relatively low detection limit, showcasing its potential in the field of photoelectric sensing.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Chemistry, Analytical
Nan Hao, Yanli Zuo, Zhen Dai, Meng Xiong, Jie Wei, Jing Qian, Kun Wang
Summary: A portable high-throughput sensor chip has been successfully developed in this work. By introducing electrochromic materials for color change detection, this chip allows for the simultaneous detection of multiple contaminants, providing a convenient choice for multiplexed assays with good sensitivity and accuracy.
ANALYTICAL CHEMISTRY
(2021)
Article
Biophysics
Lijun Ding, Honghong Hong, Liting Xiao, Qinqin Hu, Yanli Zuo, Nan Hao, Jie Wei, Kun Wang
Summary: Introducing defective ZIF-8 to enhance ECL intensity and preparing efficient ECL sensor with MoTe2 nanoparticles and ZIF-8 composites for detecting omethoate residues, which has broad linear range and low detection limit.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Multidisciplinary
Suli Jia, Chengquan Wang, Jing Qian, Xingcai Zhang, Haining Cui, Qi Zhang, Yunmeng Tian, Nan Hao, Jie Wei, Kun Wang
Summary: This new class of 2D nanosheet-based FRET biosensor utilizes vertically oriented MoS2 nanosheets on a magnetic nanocarrier, which allows for better detection by avoiding background signal and fluctuations.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Kai Zhang, Zhenqiang Fan, Yuedi Ding, Sha Zhu, Minhao Xie, Nan Hao
Summary: This paper introduces the concept of using a DNA triple helix structure to inhibit CRISPR-Cas12a activity and applies it to the design of an electrochemiluminescent biosensor for the detection of the SARS-CoV-2 RdRp gene. The biosensor achieves high sensitivity detection in real samples through inhibiting CRISPR-Cas12a activity.
ENVIRONMENTAL SCIENCE-NANO
(2022)
Article
Chemistry, Multidisciplinary
Lijun Ding, Ying Liu, Jingjie Lai, Weiran Zhu, Cunhao Fan, Nan Hao, Jie Wei, Jing Qian, Kun Wang
Summary: Organic electrochemical transistors (OECTs) exhibit excellent signal amplification, leading to improved sensing performance when combined with electrochemical analysis. A photoelectrochemical-type sensor based on OECTs shows high sensitivity, effective signal amplification, background signal reduction, and avoidance of interference from electroactive substances, offering advantages such as excellent signal amplification and ease of miniaturization.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Correction
Biophysics
Lan Ge, Henan Li, Xiaojiao Du, Mingyue Zhu, Wei Chen, Tingyan Shi, Nan Hao, Qian Liu, Kun Wang
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Biophysics
Zuorui Wen, Weiran Zhu, Fuheng You, Ruishuang Yuan, Lijun Ding, Nan Hao, Jie Wei, Kun Wang
Summary: In this study, Pd NPs/CdS nanomaterial was successfully prepared for CBZ detection. The PEC aptasensor exhibited excellent PEC performance and high specificity of the aptamer, enabling broad linear detection of CBZ at low concentrations. The sensor also showed satisfactory results when applied to lettuce samples from actual agricultural products.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Chemistry, Inorganic & Nuclear
Weiran Zhu, Nan Hao, Chen Chen, Yu Qiu, Yanli Zuo, Jie Wei, Jing Qian, Kun Wang
Summary: In this work, a dual-pathway strategy of A-site Ce substitution and nitric acid selective dissolution was proposed to enhance the performance of perovskite catalytic oxidation. The hierarchical regulation of LaMnO3 catalyst, with in situ reconstitution of B-site Mn on the surface to build a Mn-rich surface, demonstrates a steplike improvement in catalytic oxidation performance. The obtained sdLa0.7Ce0.3MnO3 material possesses good oxygen mobility, a high Mn4+/Mn3+ molar ratio, and a large specific surface area, enabling excellent catalytic oxidation performance for organics and colorimetric chemical oxygen demand detection at room temperature.
INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Analytical
Haining Cui, Keqi An, Chengquan Wang, Yangfang Chen, Suli Jia, Jing Qian, Nan Hao, Jie Wei, Kun Wang
Summary: A disposable ratiometric electrochemical aptasensor was constructed for highly sensitive detection of aflatoxin B1. Au nanoflowers on ITO surface were used for DNA anchoring and methylene blue labeling. The detection was based on the peak current intensity ratio (I-MB/I-Fc) as the signal transducer. The aptasensor exhibited a wide detection range and a low detection limit.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Engineering, Environmental
Ruishuang Yuan, Qian Liu, Honghong Hong, Hanyu Ma, Liting Xiao, Yaqi Li, Ding Jiang, Nan Hao, Kun Wang
Summary: A sensitive sensing system based on Bi NPs and BN-GQDs was designed for MC-LR detection, with a wide linear range and low detection limit. The sensor showed high stability and good reproducibility, making it suitable for actual sample detection. Good specificity was observed, allowing for sensitive and reliable detection of complex samples without interference from homologs.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Chemistry, Analytical
Yun Gao, Jie Wei, Xiang Li, Qinqin Hu, Jing Qian, Nan Hao, Kun Wang
Summary: In this study, a dual biophotoelectrode based all-solid-state multiplexed self-powered aptasensor was developed for high-throughput analysis of Ochratoxin A and Aflatoxin B1. The sensor demonstrated practicality, good stability, and anti-interference ability, while also simplifying the operation procedure and reducing preparation cost. This work not only achieved high-throughput analysis of mycotoxins, but also provided a new perspective for the construction of all-solid-state multiplexed self-powered sensors.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Analytical
Zuorui Wen, Lijun Ding, Weiran Zhu, Fuheng You, Tianshuo Wang, Nan Hao, Jie Wei, Kun Wang
Summary: A novel approach of accelerating hole transfer from Blue-TiO2 (BTiO2) to N-hydroxyphthalimide (NHPI) was explored to improve the efficiency of visible light absorption. The introduction of NHPI acted as a hole mediator, enhancing the photocurrent value of NHPI/B-TiO2 by 2.7 times. This method was further used to construct a PEC aptasensor for the sensitive detection of diazinon (DIA) with a low detection limit of 0.03 nM.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Analytical
Lijun Ding, Zhenzhen Zhang, Zuorui Wen, Fuheng You, Nan Hao, Jie Wei, Jing Qian, Kun Wang
Summary: The abuse of antibiotics can lead to bacterial resistance and pose a threat to human health. Photoelectrochemical (PEC) aptamer sensing technology, utilizing nitrogen-doped graphene nanosheet-loaded ZnIn2S4 (ZIS/NG) functional material, has been successfully applied to construct a highly sensitive 'signal-off' type PEC aptasensor for oxytetracycline (OTC) detection. The constructed aptasensor exhibits good sensitivity and selectivity, enabling the rapid detection of OTC with a relatively low detection limit.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Multidisciplinary
Weiran Zhu, Chen Chen, Zuorui Wen, Lijun Ding, Jie Wei, Jing Qian, Nan Hao, Kun Wang
Summary: We bridged the activity gap between metal-organic frameworks (Fe) and horseradish peroxidase by simulating the binding-pocket structure and adding active centers. This customized structure promoted the activation and enrichment of substrates, and the addition of gold nanoparticles led to activity superposition and synergistic enhancement.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
