Specific inhibition of bile acid transport alters plasma lipids and GLP-1

Colesevelam suppresses hepatic glycogenolysis by TGR5-mediated induction of GLP-1 action in DIO mice

(2012) Matthew J. Potthoff et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Increased Bile Acid Biosynthesis Is Associated With Irritable Bowel Syndrome With Diarrhea

(2012) Banny S. Wong et al.   Clinical Gastroenterology and Hepatology

TGR5 potentiates GLP-1 secretion in response to anionic exchange resins

(2012) Taoufiq Harach et al.   Scientific Reports

Randomised clinical trial: the ileal bile acid transporter inhibitor A3309 vs. placebo in patients with chronic idiopathic constipation - a double-blind study

(2011) M. Simrén et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Effects of A3309, an Ileal Bile Acid Transporter Inhibitor, on Colonic Transit and Symptoms in Females With Functional Constipation

(2011) Banny S Wong et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

A Randomized Placebo-Controlled Phase IIb Trial of A3309, A Bile Acid Transporter Inhibitor, for Chronic Idiopathic Constipation

(2011) William D Chey et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Constipation and Risk of Cardiovascular Disease among Postmenopausal Women

(2011) Elena Salmoirago-Blotcher et al.   AMERICAN JOURNAL OF MEDICINE

Inhibition of apical sodium-dependent bile acid transporter as a novel treatment for diabetes

(2011) Lihong Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Bile Acid Membrane Receptor TGR5: A Valuable Metabolic Target

(2011) Thijs W.H. Pols et al.   DIGESTIVE DISEASES

Bile-induced secretion of glucagon-like peptide-1: pathophysiological implications in type 2 diabetes?

(2010) Filip K. Knop   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Colesevelam improves insulin resistance in a diet-induced obesity (F-DIO) rat model by increasing the release of GLP-1

(2010) Quan Shang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Dipeptidyl Peptidase-4 Inhibitors Administered in Combination With Metformin Result in an Additive Increase in the Plasma Concentration of Active GLP-1

(2010) E M Migoya et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

S1301 The IBAT Inhibition by A3309 – A Potential Mechanism for the Treatment of Constipation

(2010) Per-Göran Gillberg et al.   GASTROENTEROLOGY

Altered Bile Acid Metabolism in Childhood Functional Constipation: Inactivation of Secretory Bile Acids by Sulfation in a Subset of Patients

(2010) Alan F Hofmann et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

The association of bile acid excretion and atherosclerotic coronary artery disease

(2010) Gideon Charach et al.   Therapeutic Advances in Gastroenterology

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

(2009) Charles Thomas et al.   Cell Metabolism

A catalogue of reporting guidelines for health research

(2009) I. Simera et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Novel pathways for glycaemic control in type 2 diabetes: focus on bile acid modulation

(2008) Eliot A. Brinton   DIABETES OBESITY & METABOLISM

Altered bile acid metabolism in patients with constipation-predominant irritable bowel syndrome and functional constipation

(2008) Hasse Abrahamsson et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY