Pharmacokinetic Modeling and Dose Selection in a Randomized, Double-Blind, Placebo-Controlled Trial of a Human Recombinant Alkaline Phosphatase in Healthy Volunteers

Alkaline phosphatase protects against renal inflammation through dephosphorylation of lipopolysaccharide and adenosine triphosphate

(2015) E Peters et al.   BRITISH JOURNAL OF PHARMACOLOGY

Reporting Guidelines for Clinical Pharmacokinetic Studies: The ClinPK Statement

(2015) Salmaan Kanji et al.   CLINICAL PHARMACOKINETICS

Biodistribution and translational pharmacokinetic modeling of a human recombinant alkaline phosphatase

(2015) Esther Peters et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Catalytic Signature of a Heat-Stable, Chimeric Human Alkaline Phosphatase with Therapeutic Potential

(2014) Tina Kiffer-Moreira et al.   PLoS One

Acute kidney injury: an increasing global concern

(2013) Norbert H Lameire et al.   LANCET

A Unified Theory of Sepsis-Induced Acute Kidney Injury

(2013) Hernando Gomez et al.   SHOCK

The severity of acute kidney injury predicts progression to chronic kidney disease

(2011) Lakhmir S. Chawla et al.   KIDNEY INTERNATIONAL

Importance of Shrinkage in Empirical Bayes Estimates for Diagnostics: Problems and Solutions

(2009) Radojka M. Savic et al.   AAPS Journal

Clinical pharmacology of exogenously administered alkaline phosphatase

(2008) P. Pickkers et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY