Disordered proteins follow diverse transition paths as they fold and bind to a partner

Quantitative Single-Molecule Three-Color Förster Resonance Energy Transfer by Photon Distribution Analysis

(2019) Anders Barth et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Measuring the average shape of transition paths during the folding of a single biological molecule

(2019) Noel Q. Hoffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Designed Mutations Alter the Binding Pathways of an Intrinsically Disordered Protein

(2019) Di Wu et al.   Scientific Reports

Diverse Folding Pathways of HIV-1 Protease Monomer on a Rugged Energy Landscape

(2019) Janghyun Yoo et al.   BIOPHYSICAL JOURNAL

Probing microscopic conformational dynamics in folding reactions by measuring transition paths

(2019) Noel Q Hoffer et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Protein folding transition path times from single molecule FRET

(2018) Hoi Sung Chung et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Transition Path Times Measured by Single-Molecule Spectroscopy

(2018) Hoi Sung Chung   JOURNAL OF MOLECULAR BIOLOGY

Study of protein folding under native conditions by rapidly switching the hydrostatic pressure inside an NMR sample cell

(2018) Cyril Charlier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-Color Single-Molecule FRET and Fluorescence Lifetime Analysis of Fast Protein Folding

(2018) Janghyun Yoo et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Transition path times of coupled folding and binding reveal the formation of an encounter complex

(2018) Flurin Sturzenegger et al.   Nature Communications

Diffusion-limited association of disordered protein by non-native electrostatic interactions

(2018) Jae-Yeol Kim et al.   Nature Communications

Reconciling transition path time and rate measurements in reactions with large entropic barriers

(2017) Dmitrii E. Makarov   JOURNAL OF CHEMICAL PHYSICS

Transition path times reveal memory effects and anomalous diffusion in the dynamics of protein folding

(2017) Rohit Satija et al.   JOURNAL OF CHEMICAL PHYSICS

Theory, simulations, and experiments show that proteins fold by multiple pathways

(2017) William A. Eaton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oligomerization of the tetramerization domain of p53 probed by two- and three-color single-molecule FRET

(2017) Hoi Sung Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct measurement of sequence-dependent transition path times and conformational diffusion in DNA duplex formation

(2017) Krishna Neupane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transition path time distribution and the transition path free energy barrier

(2016) Eli Pollak   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Microscopic interpretation of folding ϕ-values using the transition path ensemble

(2016) Robert B. Best et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct observation of transition paths during the folding of proteins and nucleic acids

(2016) K. Neupane et al.   SCIENCE

A simple two-state protein unfolds mechanically via multiple heterogeneous pathways at single-molecule resolution

(2016) Jörg Schönfelder et al.   Nature Communications

Molecular Recognition by Templated Folding of an Intrinsically Disordered Protein

(2016) Angelo Toto et al.   Scientific Reports

Binding Rate Constants Reveal Distinct Features of Disordered Protein Domains

(2015) Jakob Dogan et al.   BIOCHEMISTRY

Structural origin of slow diffusion in protein folding

(2015) H. S. Chung et al.   SCIENCE

Single-molecule chemo-mechanical unfolding reveals multiple transition state barriers in a small single-domain protein

(2015) Emily J. Guinn et al.   Nature Communications

Ultra-stable organic fluorophores for single-molecule research

(2013) Qinsi Zheng et al.   CHEMICAL SOCIETY REVIEWS

Single-molecule fluorescence probes dynamics of barrier crossing

(2013) Hoi Sung Chung et al.   NATURE

Comparing a simple theoretical model for protein folding with all-atom molecular dynamics simulations

(2013) E. R. Henry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Native contacts determine protein folding mechanisms in atomistic simulations

(2013) R. B. Best et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-Molecule Fluorescence Experiments Determine Protein Folding Transition Path Times

(2012) H. S. Chung et al.   SCIENCE

How Robust Are Protein Folding Simulations with Respect to Force Field Parameterization?

(2011) Stefano Piana et al.   BIOPHYSICAL JOURNAL

How Fast-Folding Proteins Fold

(2011) K. Lindorff-Larsen et al.   SCIENCE

Automated Prediction of Protein Association Rate Constants

(2011) Sanbo Qin et al.   STRUCTURE

Intrinsic disorder: signaling via highly specific but short-lived association

(2011) Huan-Xiang Zhou   TRENDS IN BIOCHEMICAL SCIENCES

Structure of the p53 Transactivation Domain in Complex with the Nuclear Receptor Coactivator Binding Domain of CREB Binding Protein

(2010) Chul Won Lee et al.   BIOCHEMISTRY

Extracting Rate Coefficients from Single-Molecule Photon Trajectories and FRET Efficiency Histograms for a Fast-Folding Protein

(2010) Hoi Sung Chung et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Linking folding and binding

(2009) Peter E Wright et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The Limited Role of Nonnative Contacts in the Folding Pathways of a Lattice Protein

(2009) Brian C. Gin et al.   JOURNAL OF MOLECULAR BIOLOGY

Decoding the Pattern of Photon Colors in Single-Molecule FRET

(2009) Irina V. Gopich et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Experimental determination of upper bound for transition path times in protein folding from single-molecule photon-by-photon trajectories

(2009) H. S. Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-molecule spectroscopy of the temperature-induced collapse of unfolded proteins

(2009) D. Nettels et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA