Melatonin improves cryopreservation of ram sperm by inhibiting mitochondrial permeability transition pore opening

Melatonin Inhibits Formation of Mitochondrial Permeability Transition Pores and Improves Oxidative Phosphorylation of Frozen-Thawed Ram Sperm

(2020) Yi Fang et al.   Frontiers in Endocrinology

5’-AMP-Activated Protein Kinase Regulates Goat Sperm Functions via Energy Metabolism In Vitro

(2018) Zhendong Zhu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

INHIBITION OF MITOCHONDRIAL PERMEABILITY TRANSITION PORE IMPROVED QUALITY OF FROZEN-THAWED RAM SPERM

(2018) Yi Fang et al.   CRYOBIOLOGY

Cryopreservation induces mitochondrial permeability transition in a bovine sperm model

(2018) Favián Treulen et al.   CRYOBIOLOGY

Inhibitory effect of melatonin on necroptosis via repressing the Ripk3-PGAM5-CypD-mPTP pathway attenuates cardiac microvascular ischemia-reperfusion injury

(2018) Hao Zhou et al.   JOURNAL OF PINEAL RESEARCH

Androgens modulate male-derived endothelial cell homeostasis using androgen receptor-dependent and receptor-independent mechanisms

(2016) Verónica Torres-Estay et al.   ANGIOGENESIS

Rosuvastatin postconditioning protects isolated hearts against ischemia-reperfusion injury: The role of radical oxygen species, PI3K-Akt-GSK-3β pathway, and mitochondrial permeability transition pore

(2016) Chun-Wei Liu et al.   Cardiovascular Therapeutics

Optimizing the freezing rate for ovine semen cryopreservation: Phospholipid profiles and functions of the plasma membrane and quality and fertilization of spermatozoa

(2016) Yi Fang et al.   SMALL RUMINANT RESEARCH

Physiological and Pathological Roles of the Mitochondrial Permeability Transition Pore in the Heart

(2015) Jennifer Q. Kwong et al.   Cell Metabolism

Melatonin Induces Cell Apoptosis in AGS Cells Through the Activation of JNK and P38 MAPK and the Suppression of Nuclear Factor-Kappa B: a Novel Therapeutic Implication for Gastric Cancer

(2015) Weimin Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Melatonin ameliorates amyloid beta-induced memory deficits, tau hyperphosphorylation and neurodegeneration via PI3/Akt/GSk3β pathway in the mouse hippocampus

(2015) Tahir Ali et al.   JOURNAL OF PINEAL RESEARCH

Melatonin promotes Bax sequestration to mitochondria reducing cell susceptibility to apoptosis via the lipoxygenase metabolite 5-hydroxyeicosatetraenoic acid

(2015) F. Radogna et al.   MITOCHONDRION

Ram spermatozoa migrating through artificial mucus in vitro have reduced mitochondrial membrane potential but retain their viability

(2015) Carmen Martínez-Rodríguez et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Melatonin attenuates carbon tetrachloride–induced liver fibrosis via inhibition of necroptosis

(2015) Hyo-Sun Choi et al.   Translational Research

Mediation of exogenous hydrogen sulfide in recovery of ischemic post-conditioning-induced cardioprotection via down-regulating oxidative stress and up-regulating PI3K/Akt/GSK-3β pathway in isolated aging rat hearts

(2015) Hongzhu Li et al.   Cell and Bioscience

Melatonin prevents cell death and mitochondrial dysfunction via a SIRT1-dependent mechanism during ischemic-stroke in mice

(2014) Yang Yang et al.   JOURNAL OF PINEAL RESEARCH

Mitochondrial catastrophe during doxorubicin-induced cardiotoxicity: a review of the protective role of melatonin

(2014) Jenelle Govender et al.   JOURNAL OF PINEAL RESEARCH

An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore

(2014) K. N. Alavian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylated AKT preserves stallion sperm viability and motility by inhibiting caspases 3 and 7

(2014) Juan M Gallardo Bolaños et al.   REPRODUCTION

Correction: Conditionally Immortalized Mouse Embryonic Fibroblasts Retain Proliferative Activity without Compromising Multipotent Differentiation Potential

(2013) Enyi Huang et al.   PLoS One

Physiological Roles of the Permeability Transition Pore

(2012) Catherine Brenner et al.   CIRCULATION RESEARCH

Simultaneous modulation of COX-2, p300, Akt, and Apaf-1 signaling by melatonin to inhibit proliferation and induce apoptosis in breast cancer cells

(2012) Jingshu Wang et al.   JOURNAL OF PINEAL RESEARCH

Melatonin protects human spermatozoa from apoptosis via melatonin receptor– and extracellular signal–regulated kinase-mediated pathways

(2011) Javier Espino et al.   FERTILITY AND STERILITY

Hydrogen sulfide protects cardiomyocytes from hypoxia/reoxygenation-induced apoptosis by preventing GSK-3β-dependent opening of mPTP

(2010) Ling-Ling Yao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

High endogenous melatonin concentrations enhance sperm quality and short-term in vitro exposure to melatonin improves aspects of sperm motility

(2010) A. Ortiz et al.   JOURNAL OF PINEAL RESEARCH

Inhibition of the mitochondrial permeability transition pore reduces “apoptosis like” changes during cryopreservation of stallion spermatozoa

(2010) C. Ortega Ferrusola et al.   THERIOGENOLOGY

Redox characterization of human cyclophilin D: Identification of a new mammalian mitochondrial redox sensor?

(2009) Dominique Linard et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition

(2009) A. Rasola et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Melatonin protects the mitochondria from oxidative damage reducing oxygen consumption, membrane potential, and superoxide anion production

(2008) Ana López et al.   JOURNAL OF PINEAL RESEARCH

Melatonin-enhanced hyperactivation of hamster sperm

(2008) Masakatsu Fujinoki   REPRODUCTION