Replacing the refinement for skin sensitization testing: Considerations to the implementation of adverse outcome pathway (AOP)-based defined approaches (DA) in OECD guidelines

Title
Replacing the refinement for skin sensitization testing: Considerations to the implementation of adverse outcome pathway (AOP)-based defined approaches (DA) in OECD guidelines
Authors
Keywords
Adverse outcome pathway(AOP), Defined approach (DA), Non-animal methods, OECD test guideline, Skin sensitization, Validation, Integrated Approach for Testing and Assessment (IATA)
Journal
REGULATORY TOXICOLOGY AND PHARMACOLOGY
Volume 115, Issue -, Pages 104713
Publisher
Elsevier BV
Online
2020-06-17
DOI
10.1016/j.yrtph.2020.104713

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