Journal
RADIOTHERAPY AND ONCOLOGY
Volume 148, Issue -, Pages 140-142Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.radonc.2020.04.016
Keywords
Radiotherapy; Dose; Target volume; Imaging; Head and Neck cancer
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Advances in diagnostic imaging create opportunities for improved therapeutic targeting of cancer but conceptual thinking about radiotherapy target volume definition and dose-prescription is not keeping up. In this opinion paper we discuss how modern imaging can contribute to new concepts for radiotherapy dose-prescription and target volume definition illustrated by the example of head and neck cancer. These new insights have the potential to significantly reduce radiation associated toxicity and may have important impact on the combination of radiotherapy with systemic cancer therapies. (C) 2020 Elsevier B.V. All rights reserved.
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