Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 117, Issue 29, Pages 16848-16855Publisher
NATL ACAD SCIENCES
DOI: 10.1073/pnas.2001779117
Keywords
acoustic tweezers; acoustic radiation force; kidney stones
Categories
Funding
- National Institutes of Health [P01 DK043881, K01 DK104854, R01 EB007643]
- Russian Foundation for Basic Research [2002-00139]
- National Space Biomedical Research Institute through NASA [NCC 9-58]
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In certain medical applications, transmitting an ultrasound beam through the skin to manipulate a solid object within the human body would be beneficial. Such applications include, for example, controlling an ingestible camera or expelling a kidney stone. In this paper, ultrasound beams of specific shapes were designed by numerical modeling and produced using a phased array. These beams were shown to levitate and electronically steer solid objects (3-mm-diameter glass spheres), along preprogrammed paths, in a water bath, and in the urinary bladders of live pigs. Deviation from the intended path was on average <10%. No injury was found on the bladder wall or intervening tissue.
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