Antifibrotic role of low-dose mitomycin-c-induced cellular senescence in trabeculectomy models

Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis

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Ki67, PCNA, and MCM proteins: Markers of proliferation in the diagnosis of breast cancer

(2016) Miroslava Juríková et al.   ACTA HISTOCHEMICA

Induction of fibroblast senescence generates a non-fibrogenic myofibroblast phenotype that differentially impacts on cancer prognosis

(2016) Massimiliano Mellone et al.   Aging-US

TGF-β Signaling from Receptors to Smads

(2016) Akiko Hata et al.   Cold Spring Harbor Perspectives in Biology

Plasminogen activator inhibitor 1, fibroblast apoptosis resistance, and aging-related susceptibility to lung fibrosis

(2015) Wen-Tan Huang et al.   EXPERIMENTAL GERONTOLOGY

Diverse functions of matrix metalloproteinases during fibrosis

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Reduction of Conjunctival Fibrosis After Trabeculectomy Using Topical α-Lipoic Acid in Rabbit Eyes

(2014) Metin Ekinci et al.   JOURNAL OF GLAUCOMA

Reversal of Persistent Fibrosis in Aging by Targeting Nox4-Nrf2 Redox Imbalance

(2014) L. Hecker et al.   Science Translational Medicine

Silibinin inhibits myofibroblast transdifferentiation in human tenon fibroblasts and reduces fibrosis in a rabbit trabeculectomy model

(2013) Yi-Hao Chen et al.   ACTA OPHTHALMOLOGICA

Persistent DNA damage caused by low levels of mitomycin C induces irreversible cell senescence

(2012) Elise McKenna et al.   CELL CYCLE

Connexin43 Modulation Inhibits Scarring in a Rabbit Eye Glaucoma Trabeculectomy Model

(2012) Narmadai C. Deva et al.   INFLAMMATION

Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis

(2012) Alfiya Akhmetshina et al.   Nature Communications

Glucosamine inhibits epithelial-to-mesenchymal transition and migration of retinal pigment epithelium cells in culture and morphologic changes in a mouse model of proliferative vitreoretinopathy

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Intraocular Pressure: Modulation as Treatment for Glaucoma

(2011) Joseph Caprioli et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Global estimates of visual impairment: 2010

(2011) Donatella Pascolini et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Long-Term Topical Antiglaucoma Medications Cause Enhanced Tenon’s Capsule Fibroblast Proliferation and Abnormal TGF-β and MMP Expressions: Potential Effects on Glaucoma Filtering Surgery

(2011) Fei Leng et al.   CURRENT EYE RESEARCH

The Changing Conceptual Basis of Trabeculectomy: A Review of Past and Current Surgical Techniques

(2011) M. Reza Razeghinejad et al.   SURVEY OF OPHTHALMOLOGY

Mechanisms of pathological scarring: Role of myofibroblasts and current developments

(2011) Vincent Sarrazy et al.   WOUND REPAIR AND REGENERATION

The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing

(2010) Joon-Il Jun et al.   NATURE CELL BIOLOGY

Inhibition of phosphatidylinositol 3-kinase signaling in hepatic stellate cells blocks the progression of hepatic fibrosis

(2009) Gakuhei Son et al.   HEPATOLOGY

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

(2009) Florence Debacq-Chainiaux et al.   Nature Protocols

Differences in collagen architecture between keloid, hypertrophic scar, normotrophic scar, and normal skin: An objective histopathological analysis

(2009) Pauline D. H. M. Verhaegen et al.   WOUND REPAIR AND REGENERATION

Evaluation of the Value of Frozen Tissue Section Used as “Gold Standard” for Immunohistochemistry

(2008) Shan-Rong Shi et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Fibroblast-specific perturbation of transforming growth factor β signaling provides insight into potential pathogenic mechanisms of scleroderma-associated lung fibrosis: Exaggerated response to alveolar epithelial injury in a novel mouse model

(2008) Rachel K. Hoyles et al.   ARTHRITIS AND RHEUMATISM

Validation of putative reference genes for gene expression studies in human hepatocellular carcinoma using real-time quantitative RT-PCR

(2008) Vito R Cicinnati et al.   BMC CANCER

Wound repair and regeneration

(2008) Geoffrey C. Gurtner et al.   NATURE

Regulation of CCN2 mRNA expression and promoter activity in activated hepatic stellate cells

(2008) Andrew Leask et al.   Journal of Cell Communication and Signaling