NLRP3 inflammasome inhibition attenuates sepsis-induced platelet activation and prevents multi-organ injury in cecal-ligation puncture

The roles of NLRP3 inflammasome in bacterial infection

(2020) Yanjun Zhong et al.   MOLECULAR IMMUNOLOGY

Sepsis associated acute kidney injury

(2019) Jason T Poston et al.   BMJ-British Medical Journal

The selective Nlrp3 inflammasome inhibitor Mcc950 attenuates lung ischemia-reperfusion injury

(2018) Kai-Ying Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016

(2017) Andrew Rhodes et al.   INTENSIVE CARE MEDICINE

Activation of NLRP3 inflammasomes contributes to hyperhomocysteinemia-aggravated inflammation and atherosclerosis in apoE-deficient mice

(2017) Renqing Wang et al.   LABORATORY INVESTIGATION

Artemisinin protects mice against burn sepsis through inhibiting NLRP3 inflammasome activation

(2016) Huibao Long et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Complement-induced activation of the cardiac NLRP3 inflammasome in sepsis

(2016) Miriam Kalbitz et al.   FASEB JOURNAL

Recent advances in pathophysiology and biomarkers of sepsis-induced acute kidney injury

(2016) Ilaria Umbro et al.   JOURNAL OF INFECTION

Exogenous Carbon Monoxide Decreases Sepsis-Induced Acute Kidney Injury and Inhibits NLRP3 Inflammasome Activation in Rats

(2015) Peng Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis

(2015) Jong-Seok Moon et al.   JOURNAL OF CLINICAL INVESTIGATION

Curcumin suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock

(2015) Zizhen Gong et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Sepsis-Associated Acute Kidney Injury

(2015) Rashid Alobaidi et al.   SEMINARS IN NEPHROLOGY

NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases

(2015) Amna Abderrazak et al.   Redox Biology

Emerging roles for platelets as immune and inflammatory cells

(2014) C. N. Morrell et al.   BLOOD

Hemin inhibits NLRP3 inflammasome activation in sepsis-induced acute lung injury, involving heme oxygenase-1

(2014) Yun-peng Luo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The role of platelets in sepsis

(2014) Cornelis van ’t Veer et al.   THROMBOSIS AND HAEMOSTASIS

Platelets mediate increased endothelium permeability in dengue through NLRP3-inflammasome activation

(2013) E. D. Hottz et al.   BLOOD

Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock

(2013) Kairui Mao et al.   CELL RESEARCH

Lipopolysaccharide Stimulates Platelets through an IL-1  Autocrine Loop

(2013) G. T. Brown et al.   JOURNAL OF IMMUNOLOGY

Activation of Nod-Like Receptor Protein 3 Inflammasomes Turns on Podocyte Injury and Glomerular Sclerosis in Hyperhomocysteinemia

(2012) Chun Zhang et al.   HYPERTENSION

Is worsening multiple organ failure the cause of death in patients with severe sepsis?*

(2011) Jean-Louis Vincent et al.   CRITICAL CARE MEDICINE

Transcutaneous measurement of glomerular filtration rate using FITC-sinistrin in rats

(2009) Daniel Schock-Kusch et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Acute kidney injury in septic shock: clinical outcomes and impact of duration of hypotension prior to initiation of antimicrobial therapy

(2008) Sean M. Bagshaw et al.   INTENSIVE CARE MEDICINE