The function of a heterozygous p53 mutation in a Li-Fraumeni syndrome patient

Intratumour heterogeneity of p53 expression; causes and consequences

(2019) Yuezhen Xue et al.   JOURNAL OF PATHOLOGY

Reciprocity of Action of Increasing Oct4 and Repressing p53 in Transdifferentiation of Mouse Embryonic Fibroblasts into Cardiac Myocytes

(2018) Hongran Wang et al.   Cellular Reprogramming

Composite Adrenocortical Carcinoma and Neuroblastoma in an Infant With a TP53 Germline Mutation

(2018) Yue-Jia Tang et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Optimizing the method for generation of integration-free induced pluripotent stem cells from human peripheral blood

(2018) Haihui Gu et al.   Stem Cell Research & Therapy

Two approaches reveal a new paradigm of ‘switchable or genetics-influenced allele-specific DNA methylation’ with potential in human disease

(2017) Suzanne N Martos et al.   Cell Discovery

p53 isoform Δ133p53 promotes efficiency of induced pluripotent stem cells and ensures genomic integrity during reprogramming

(2016) Lu Gong et al.   Scientific Reports

Revisiting Li-Fraumeni Syndrome From TP53 Mutation Carriers

(2015) Gaëlle Bougeard et al.   JOURNAL OF CLINICAL ONCOLOGY

Germline Mutations in Predisposition Genes in Pediatric Cancer

(2015) Jinghui Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Developmental Dynamics and Disease Potential of Random Monoallelic Gene Expression

(2014) Anne-Valerie Gendrel et al.   DEVELOPMENTAL CELL

Random monoallelic expression: regulating gene expression one allele at a time

(2014) Mélanie A. Eckersley-Maslin et al.   TRENDS IN GENETICS

The p53–PUMA axis suppresses iPSC generation

(2013) Yanxin Li et al.   Nature Communications

An Opposite Effect of the CDK Inhibitor, p18INK4c on Embryonic Stem Cells Compared with Tumor and Adult Stem Cells

(2012) Yanxin Li et al.   PLoS One

Autosomal monoallelic expression in the mouse

(2012) Lillian M Zwemer et al.   GENOME BIOLOGY

Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures

(2011) Bin-Kuan Chou et al.   CELL RESEARCH

Evolutionary diversity and developmental regulation of X-chromosome inactivation

(2011) Martin Escamilla-Del-Arenal et al.   HUMAN GENETICS

Generation of Induced Pluripotent Stem Cells from CD34+ Cells across Blood Drawn from Multiple Donors with Non-Integrating Episomal Vectors

(2011) Amanda A. Mack et al.   PLoS One

p53 mutation and loss have different effects on tumourigenesis in a novel mouse model of pleomorphic rhabdomyosarcoma

(2010) Brendan Doyle et al.   JOURNAL OF PATHOLOGY

The promises and perils of p53

(2009) Valery Krizhanovsky et al.   NATURE

Linking the p53 tumour suppressor pathway to somatic cell reprogramming

(2009) Teruhisa Kawamura et al.   NATURE

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

(2009) Rosa M. Marión et al.   NATURE

Suppression of induced pluripotent stem cell generation by the p53–p21 pathway

(2009) Hyenjong Hong et al.   NATURE

Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

(2009) Jochen Utikal et al.   NATURE

Induced pluripotent stem cells and reprogramming: seeing the science through the hype

(2009) Juan Carlos Izpisúa Belmonte et al.   NATURE REVIEWS GENETICS

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

(2009) J. P. Morton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Biology of the Tumor Suppressor p53

(2008) Andreas C. Joerger et al.   Annual Review of Biochemistry

Attenuated p53 activation in tumour-associated stromal cells accompanies decreased sensitivity to etoposide and vincristine

(2008) A C Dudley et al.   BRITISH JOURNAL OF CANCER

Disease-Specific Induced Pluripotent Stem Cells

(2008) In-Hyun Park et al.   CELL

In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute

(2008) E M Michalak et al.   CELL DEATH AND DIFFERENTIATION

Two Supporting Factors Greatly Improve the Efficiency of Human iPSC Generation

(2008) Yang Zhao et al.   Cell Stem Cell