Brain mechanisms of insomnia: new perspectives on causes and consequences

Introducing Network Intervention Analysis to Investigate Sequential, Symptom-Specific Treatment Effects: A Demonstration in Co-Occurring Insomnia and Depression

(2019) Tessa F. Blanken et al.   PSYCHOTHERAPY AND PSYCHOSOMATICS

Haunted by the past: old emotions remain salient in insomnia disorder

(2019) Rick Wassing et al.   BRAIN

Data-Driven Analysis of EEG Reveals Concomitant Superficial Sleep During Deep Sleep in Insomnia Disorder

(2019) Julie Anja Engelhard Christensen et al.   Frontiers in Neuroscience

Revisiting the value of polysomnographic data in insomnia: more than meets the eye

(2019) Thomas Andrillon et al.   SLEEP MEDICINE

Use of Actigraphy for the Evaluation of Sleep Disorders and Circadian Rhythm Sleep-Wake Disorders: An American Academy of Sleep Medicine Clinical Practice Guideline

(2018) Michael T. Smith et al.   Journal of Clinical Sleep Medicine

Anatomy and white matter connections of the orbitofrontal gyrus

(2018) Joshua D. Burks et al.   JOURNAL OF NEUROSURGERY

Does online insomnia treatment reduce depressive symptoms? A randomized controlled trial in individuals with both insomnia and depressive symptoms

(2018) T. van der Zweerde et al.   PSYCHOLOGICAL MEDICINE

Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

(2018) Michael J. Gandal et al.   SCIENCE

Maternal sleep during pregnancy and poor fetal outcomes: A scoping review of the literature with meta-analysis

(2018) Jane Warland et al.   SLEEP MEDICINE REVIEWS

Sleep and emotional processing

(2018) Daniela Tempesta et al.   SLEEP MEDICINE REVIEWS

Phasic locus coeruleus activity regulates cortical encoding of salience information

(2018) Elena M. Vazey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abnormal Locus Coeruleus Sleep Activity Alters Sleep Signatures of Memory Consolidation and Impairs Place Cell Stability and Spatial Memory

(2018) Kevin M. Swift et al.   CURRENT BIOLOGY

A Pilot, Randomized Clinical Trial of Bedtime Doses of Prazosin Versus Placebo in Suicidal Posttraumatic Stress Disorder Patients With Nightmares

(2018) William Vaughn McCall et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

REM theta activity predicts re-experiencing symptoms after exposure to a traumatic film

(2018) M. Roxanne Sopp et al.   SLEEP MEDICINE

Sleep Is for Forgetting

(2017) Gina R. Poe   JOURNAL OF NEUROSCIENCE

Pharmacological Modulation of Noradrenergic Arousal Circuitry Disrupts Functional Connectivity of the Locus Ceruleus in Humans

(2017) Andrew H. Song et al.   JOURNAL OF NEUROSCIENCE

REM sleep selectively prunes and maintains new synapses in development and learning

(2017) Wei Li et al.   NATURE NEUROSCIENCE

The large-scale functional connectivity correlates of consciousness and arousal during the healthy and pathological human sleep cycle

(2017) Enzo Tagliazucchi et al.   NEUROIMAGE

Sleep and cognitive performance: cross-sectional associations in the UK Biobank

(2017) Simon D. Kyle et al.   SLEEP MEDICINE

Heart rate variability in insomnia patients: A critical review of the literature

(2017) Kirsty L. Dodds et al.   SLEEP MEDICINE REVIEWS

The prevalence of insomnia in the general population in China: A meta-analysis

(2017) Xiao-Lan Cao et al.   PLoS One

Cognitive Behavioral Therapy for Insomnia Enhances Depression Outcome in Patients with Comorbid Major Depressive Disorder and Insomnia

(2017) Rachel Manber et al.   SLEEP

Inter-individual Differences in the Dynamics of Sleep Homeostasis

(2017) Thomas Rusterholz et al.   SLEEP

Association between a Serotonin Transporter Length Polymorphism and Primary Insomnia

(2017) Michael Deuschle et al.   SLEEP

Effects of the Social Environment and Stress on Glucocorticoid Receptor Gene Methylation: A Systematic Review

(2016) Gustavo Turecki et al.   BIOLOGICAL PSYCHIATRY

Insomnia and the risk of depression: a meta-analysis of prospective cohort studies

(2016) Liqing Li et al.   BMC Psychiatry

Sex differences in the locus coeruleus-norepinephrine system and its regulation by stress

(2016) Debra A. Bangasser et al.   BRAIN RESEARCH

Time to wake up: No impact of COMT Val158Met gene variation on circadian preferences, arousal regulation and sleep

(2016) Philippe Jawinski et al.   CHRONOBIOLOGY INTERNATIONAL

Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits

(2016) Jacqueline M Lane et al.   NATURE GENETICS

Internet-Delivered Cognitive Behavioral Therapy to Treat Insomnia: A Systematic Review and Meta-Analysis

(2016) Michael Seyffert et al.   PLoS One

Emergence of Sex Differences in Insomnia Symptoms in Adolescents: A Large-Scale School-Based Study

(2016) Jihui Zhang et al.   SLEEP

Regional Patterns of Elevated Alpha and High-Frequency Electroencephalographic Activity during Nonrapid Eye Movement Sleep in Chronic Insomnia: A Pilot Study

(2016) Brady A. Riedner et al.   SLEEP

I Keep a Close Watch on This Heart of Mine: Increased Interoception in Insomnia

(2016) Yishul Wei et al.   SLEEP

Artificial Outdoor Nighttime Lights Associate with Altered Sleep Behavior in the American General Population

(2016) Maurice M. Ohayon et al.   SLEEP

Preexisting mild sleep disturbance as a vulnerability factor for inflammation-induced depressed mood: a human experimental study

(2016) H J Cho et al.   Translational Psychiatry

Emergence of Sex Differences in Insomnia Symptoms in Adolescents: A Large-Scale School-Based Study

(2016) Jihui Zhang et al.   SLEEP

Regional Patterns of Elevated Alpha and High-Frequency Electroencephalographic Activity during Nonrapid Eye Movement Sleep in Chronic Insomnia: A Pilot Study

(2016) Brady A. Riedner et al.   SLEEP

I Keep a Close Watch on This Heart of Mine: Increased Interoception in Insomnia

(2016) Yishul Wei et al.   SLEEP

Artificial Outdoor Nighttime Lights Associate with Altered Sleep Behavior in the American General Population

(2016) Maurice M. Ohayon et al.   SLEEP

Cardiac autonomic function during sleep: Effects of alcohol dependence and evidence of partial recovery with abstinence

(2015) Massimiliano de Zambotti et al.   ALCOHOL

Slow wave sleep in the chronically fatigued: Power spectra distribution patterns in chronic fatigue syndrome and primary insomnia

(2015) Daniel Neu et al.   CLINICAL NEUROPHYSIOLOGY

Organization of the Locus Coeruleus-Norepinephrine System

(2015) Lindsay A. Schwarz et al.   CURRENT BIOLOGY

DNA methylation, early life environment and health outcomes

(2015) Colter Mitchell et al.   PEDIATRIC RESEARCH

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Internet Treatment Addressing either Insomnia or Depression, for Patients with both Diagnoses: A Randomized Trial

(2015) Kerstin Blom et al.   SLEEP

A Longitudinal Twin Study of Insomnia Symptoms in Adults

(2015) Mackenzie J. Lind et al.   SLEEP

Early-life origin of adult insomnia: does prenatal–early-life stress play a role?

(2015) Laura Palagini et al.   SLEEP MEDICINE

Emotional memory processing is influenced by sleep quality

(2015) Daniela Tempesta et al.   SLEEP MEDICINE

Cross-cultural and comparative epidemiology of insomnia: the Diagnostic and Statistical Manual (DSM), International Classification of Diseases (ICD) and International Classification of Sleep Disorders (ICSD)

(2015) Ka-Fai Chung et al.   SLEEP MEDICINE

Trends in insomnia and excessive daytime sleepiness among US adults from 2002 to 2012

(2015) Earl S. Ford et al.   SLEEP MEDICINE

Social interactions, emotion and sleep: A systematic review and research agenda

(2015) Louise Beattie et al.   SLEEP MEDICINE REVIEWS

Sleep alterations following exposure to stress predict fear-associated memory impairments in a rodent model of PTSD

(2015) William M. Vanderheyden et al.   EXPERIMENTAL BRAIN RESEARCH

Internet Treatment Addressing either Insomnia or Depression, for Patients with both Diagnoses: A Randomized Trial

(2015) Kerstin Blom et al.   SLEEP

A Longitudinal Twin Study of Insomnia Symptoms in Adults

(2015) Mackenzie J. Lind et al.   SLEEP

Increased insula coactivation with salience networks in insomnia

(2014) Michael C. Chen et al.   BIOLOGICAL PSYCHOLOGY

Electrical stimulation of a small brain area reversibly disrupts consciousness

(2014) Mohamad Z. Koubeissi et al.   EPILEPSY & BEHAVIOR

The role of vulnerability in stress-related insomnia, social support and coping styles on incidence and persistence of insomnia

(2014) Denise C. Jarrin et al.   JOURNAL OF SLEEP RESEARCH

The forgotten insular cortex: Its role on recognition memory formation

(2014) Federico Bermudez-Rattoni   NEUROBIOLOGY OF LEARNING AND MEMORY

Designer receptor manipulations reveal a role of the locus coeruleus noradrenergic system in isoflurane general anesthesia

(2014) E. M. Vazey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Associations between Subjective Sleep Quality and Brain Volume in Gulf War Veterans

(2014) Linda L. Chao et al.   SLEEP

Altered Emotion Perception in Insomnia Disorder

(2014) Simon D. Kyle et al.   SLEEP

Increased Electroencephalographic High Frequencies during the Sleep Onset Period in Patients with Restless Legs Syndrome

(2014) Raffaele Ferri et al.   SLEEP

Insomnia Disorder is Associated with Increased Amygdala Reactivity to Insomnia-Related Stimuli

(2014) Chiara Baglioni et al.   SLEEP

Eveningness and Insomnia: Independent Risk Factors of Nonremission in Major Depressive Disorder

(2014) Joey Wing Yan Chan et al.   SLEEP

Stress and Sleep Reactivity: A Prospective Investigation of the Stress-Diathesis Model of Insomnia

(2014) Christopher L. Drake et al.   SLEEP

Periodic Leg Movements during Sleep Are Associated with Polymorphisms in BTBD9, TOX3/BC034767, MEIS1, MAP2K5/SKOR1, and PTPRD

(2014) Hyatt Moore et al.   SLEEP

Trauma exposure and sleep: using a rodent model to understand sleep function in PTSD

(2014) William M. Vanderheyden et al.   EXPERIMENTAL BRAIN RESEARCH

The caudate: a key node in the neuronal network imbalance of insomnia?

(2013) Diederick Stoffers et al.   BRAIN

Sleep Loss and Hypertension: A Systematic Review

(2013) Laura Palagini et al.   CURRENT PHARMACEUTICAL DESIGN

Reduced anterior internal capsule white matter integrity in primary insomnia

(2013) Kai Spiegelhalder et al.   HUMAN BRAIN MAPPING

Pitfalls of predicting complex traits from SNPs

(2013) Naomi R. Wray et al.   NATURE REVIEWS GENETICS

Susceptibility to Declarative Memory Interference is Pronounced in Primary Insomnia

(2013) Hermann Griessenberger et al.   PLoS One

Behavioral and biochemical dissociation of arousal and homeostatic sleep need influenced by prior wakeful experience in mice

(2013) A. Suzuki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased Rostral Anterior Cingulate Cortex Volume in Chronic Primary Insomnia

(2013) John W. Winkelman et al.   SLEEP

Brain Gray Matter Deficits in Patients with Chronic Primary Insomnia

(2013) Eun Yeon Joo et al.   SLEEP

Predeployment Sleep Duration and Insomnia Symptoms as Risk Factors for New-Onset Mental Health Disorders Following Military Deployment

(2013) Philip Gehrman et al.   SLEEP

Measuring Sleep: Accuracy, Sensitivity, and Specificity of Wrist Actigraphy Compared to Polysomnography

(2013) Miguel Marino et al.   SLEEP

A two-year prospective study on the frequency and co-occurrence of insomnia and sleep-disordered breathing symptoms in a primary care population

(2013) Barry Krakow et al.   SLEEP MEDICINE

Genetic polymorphisms in the aryl hydrocarbon receptor-signaling pathway and sleep disturbances in middle-aged women

(2013) Ayelet Ziv-Gal et al.   SLEEP MEDICINE

The role of actigraphy in the assessment of primary insomnia: a retrospective study

(2013) Vincenzo Natale et al.   SLEEP MEDICINE

A 10-year trend of insomnia prevalence in the adult Norwegian population

(2013) Ståle Pallesen et al.   SLEEP MEDICINE

Early-life trauma is associated with rapid eye movement sleep fragmentation among military veterans

(2012) Salvatore P. Insana et al.   BIOLOGICAL PSYCHOLOGY

Motor restlessness, sleep disturbances, thermal sensory alterations and elevated serum iron levels in Btbd9 mutant mice

(2012) Mark P. DeAndrade et al.   HUMAN MOLECULAR GENETICS

Processing of Emotional Reactivity and Emotional Memory over Sleep

(2012) B. Baran et al.   JOURNAL OF NEUROSCIENCE

Placebo-controlled comparison of prazosin and cognitive–behavioral treatments for sleep disturbances in US Military Veterans

(2012) Vera M.T. van Berkel et al.   JOURNAL OF PSYCHOSOMATIC RESEARCH

Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study

(2012) Karen Barnett et al.   LANCET

α-Adrenergic Receptor Function, Arousal and Sleep: Mechanisms and Therapeutic Implications

(2012) M. Broese et al.   PHARMACOPSYCHIATRY

Enhanced Hippocampal Long-Term Potentiation and Fear Memory in Btbd9 Mutant Mice

(2012) Mark P. DeAndrade et al.   PLoS One

Increased serotonin transporter gene (SERT) DNA methylation is associated with bullying victimization and blunted cortisol response to stress in childhood: a longitudinal study of discordant monozygotic twins

(2012) I. Ouellet-Morin et al.   PSYCHOLOGICAL MEDICINE

Increased Prevalence of Insomnia and Changes in Hypnotics Use in England over 15 Years: Analysis of the 1993, 2000, and 2007 National Psychiatric Morbidity Surveys

(2012) Maria Calem et al.   SLEEP

Repeated Melatonin Supplementation Improves Sleep in Hypertensive Patients Treated with Beta-Blockers: A Randomized Controlled Trial

(2012) Frank A.J.L. Scheer et al.   SLEEP

PER3 Polymorphism and Insomnia Severity in Alcohol Dependence

(2012) Kirk J. Brower et al.   SLEEP

Enhanced emotional reactivity after selective REM sleep deprivation in humans: an fMRI study

(2012) Alejandra Rosales-Lagarde et al.   Frontiers in Behavioral Neuroscience

Neuroticism Mediates the Relationship Between Childhood Adversity and Adult Sleep Quality

(2011) Holly J. Ramsawh et al.   Behavioral Sleep Medicine

A Meta-Analysis of Electroencephalographic Sleep in Depression: Evidence for Genetic Biomarkers

(2011) Vivek Pillai et al.   BIOLOGICAL PSYCHIATRY

REM Sleep Depotentiates Amygdala Activity to Previous Emotional Experiences

(2011) Els van der Helm et al.   CURRENT BIOLOGY

Abnormal amygdala connectivity in patients with primary insomnia: Evidence from resting state fMRI

(2011) Zhaoyang Huang et al.   EUROPEAN JOURNAL OF RADIOLOGY

Local sleep in awake rats

(2011) Vladyslav V. Vyazovskiy et al.   NATURE

Regional Slow Waves and Spindles in Human Sleep

(2011) Yuval Nir et al.   NEURON

Sleep, vigilance, and thermosensitivity

(2011) Nico Romeijn et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

(Mis)perception of sleep in insomnia: A puzzle and a resolution.

(2011) Allison G. Harvey et al.   PSYCHOLOGICAL BULLETIN

Sleep Reactivity and Insomnia: Genetic and Environmental Influences

(2011) Christopher L. Drake et al.   SLEEP

Insomnia and the Performance of US Workers: Results from the America Insomnia Survey

(2011) Ronald C. Kessler et al.   SLEEP

Cyclic alternating pattern (CAP): The marker of sleep instability

(2011) Liborio Parrino et al.   SLEEP MEDICINE REVIEWS

Genome-Wide Association Study Identifies Novel Restless Legs Syndrome Susceptibility Loci on 2p14 and 16q12.1

(2011) Juliane Winkelmann et al.   PLoS Genetics

Adenosine A2A receptor gene: Evidence for association of risk variants with panic disorder and anxious personality

(2010) Christa Hohoff et al.   JOURNAL OF PSYCHIATRIC RESEARCH

British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders

(2010) SJ Wilson et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Measuring the error in sleep estimation in normal subjects and in patients with insomnia

(2010) MAURO MANCONI et al.   JOURNAL OF SLEEP RESEARCH

Sleep impairment during pregnancy: Possible implications on mother–infant relationship

(2010) Gabriel Natan Pires et al.   MEDICAL HYPOTHESES

Napping promotes inter-session habituation to emotional stimuli

(2010) Edward F. Pace-Schott et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Phenotypic Complexity, Measurement Bias, and Poor Phenotypic Resolution Contribute to the Missing Heritability Problem in Genetic Association Studies

(2010) Sophie van der Sluis et al.   PLoS One

Doing with less sleep remains a dream

(2010) E. J. W. Van Someren   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shift from Hippocampal to Neocortical Centered Retrieval Network with Consolidation

(2009) A. Takashima et al.   JOURNAL OF NEUROSCIENCE

Overnight emotional adaptation to negative stimuli is altered by REM sleep deprivation and is correlated with intervening dream emotions

(2009) JESSICA LARA-CARRASCO et al.   JOURNAL OF SLEEP RESEARCH

Prevalence of insomnia symptoms in sleep laboratory patients with and without sleep apnea

(2009) Christine Hagen et al.   PSYCHIATRY RESEARCH

Paradoxical insomnia: The role of CAP and arousals in sleep misperception

(2009) Liborio Parrino et al.   SLEEP MEDICINE

Night-to-night sleep variability in older adults with and without chronic insomnia

(2009) Daniel J. Buysse et al.   SLEEP MEDICINE

Searching for the daytime impairments of primary insomnia

(2009) Julia A. Shekleton et al.   SLEEP MEDICINE REVIEWS

Impact of beta-blockers on sleep in patients with mild hypertension: a randomized trial between nebivolol and metoprolol

(2008) Mehmet Birhan Yilmaz et al.   ADVANCES IN THERAPY

PHYLOGENETIC ANALYSIS OF THE ECOLOGY AND EVOLUTION OF MAMMALIAN SLEEP

(2008) Isabella Capellini et al.   EVOLUTION

Sleep loss affects vigilance: effects of chronic insomnia and sleep therapy

(2008) ELLEMARIJE ALTENA et al.   JOURNAL OF SLEEP RESEARCH

The relationship between insomnia and body temperatures

(2008) Leon C. Lack et al.   SLEEP MEDICINE REVIEWS

Prazosin Effects on Objective Sleep Measures and Clinical Symptoms in Civilian Trauma Posttraumatic Stress Disorder: A Placebo-Controlled Study

(2007) Fletcher B. Taylor et al.   BIOLOGICAL PSYCHIATRY

The Neural Bases of Emotion Regulation: Reappraisal and Suppression of Negative Emotion

(2007) Philippe R. Goldin et al.   BIOLOGICAL PSYCHIATRY

Stress-induced changes in sleep in rodents: Models and mechanisms

(2007) Aaron C. Pawlyk et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS