Baricitinib: A Review of Pharmacology, Safety, and Emerging Clinical Experience in COVID‐19

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China

(2020) Dawei Wang et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Abnormal Coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia

(2020) Ning Tang et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

COVID-19: combining antiviral and anti-inflammatory treatments

(2020) Justin Stebbing et al.   LANCET INFECTIOUS DISEASES

Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions

(2020) Yvan Jamilloux et al.   AUTOIMMUNITY REVIEWS

COVID-19 infection and rheumatoid arthritis: Faraway, so close!

(2020) Ennio Giulio Favalli et al.   AUTOIMMUNITY REVIEWS

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

(2020) Carly G.K. Ziegler et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Functional exhaustion of antiviral lymphocytes in COVID-19 patients

(2020) Meijuan Zheng et al.   Cellular & Molecular Immunology

Bacterial and fungal co-infection in individuals with coronavirus: A rapid review to support COVID-19 antimicrobial prescribing

(2020) Timothy M Rawson et al.   CLINICAL INFECTIOUS DISEASES

Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China

(2020) Chuan Qin et al.   CLINICAL INFECTIOUS DISEASES

Host-Directed Antiviral Therapy

(2020) Naveen Kumar et al.   CLINICAL MICROBIOLOGY REVIEWS

Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19)

(2020) James M. Sanders et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy

(2020) Giacomo Grasselli et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Type I IFN immunoprofiling in COVID-19 patients

(2020) Sophie Trouillet-Assant et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Clinical and immunological features of severe and moderate coronavirus disease 2019

(2020) Guang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Bacteremia and Blood Culture Utilization During COVID-19 Surge in New York City

(2020) Jorge Sepulveda et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Thromboinflammation and the hypercoagulability of COVID‐19

(2020) Jean M. Connors et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Hypercoagulability of COVID‐19 patients in Intensive Care Unit. A Report of Thromboelastography Findings and other Parameters of Hemostasis

(2020) Mauro Panigada et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

(2020) Fei Zhou et al.   LANCET

COVID-19: consider cytokine storm syndromes and immunosuppression

(2020) Puja Mehta et al.   LANCET

Remdesivir for the Treatment of Covid-19 — Preliminary Report

(2020) John H. Beigel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19

(2020) Muthiah Vaduganathan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study

(2020) Annemarie B Docherty et al.   BMJ-British Medical Journal

HiJAKing SARS-CoV-2? The potential role of JAK inhibitors in the management of COVID-19

(2020) Francesca Romana Spinelli et al.   Science Immunology

The Role of Cytokines including Interleukin-6 in COVID-19 induced Pneumonia and Macrophage Activation Syndrome-Like Disease

(2020) Dennis McGonagle et al.   AUTOIMMUNITY REVIEWS

Thromboembolic Safety Reporting of Tofacitinib and Baricitinib: An Analysis of the WHO VigiBase

(2020) Enriqueta Vallejo-Yagüe et al.   DRUG SAFETY

Clinical characteristics of coronavirus disease 2019 (COVID-19) in China: A systematic review and meta-analysis

(2020) Leiwen Fu et al.   JOURNAL OF INFECTION

Symptomatic elevation creatine kinase following treatment of rheumatoid arthritis with baricitinib

(2019) Pamela Anjara et al.   CLINICAL RHEUMATOLOGY

Feasibility and biological rationale of repurposing sunitinib and erlotinib for dengue treatment

(2018) Szu-Yuan Pu et al.   ANTIVIRAL RESEARCH

Mechanisms of clathrin-mediated endocytosis

(2018) Marko Kaksonen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

OUP accepted manuscript

(2018)   RHEUMATOLOGY

Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects

(2017) Elena Bekerman et al.   JOURNAL OF CLINICAL INVESTIGATION

The emerging safety profile of JAK inhibitors in rheumatic disease

(2017) Kevin L. Winthrop   Nature Reviews Rheumatology

Tofacitinib

(2014) Deepti Vyas et al.   ANNALS OF PHARMACOTHERAPY

Genetic studies reveal an unexpected negative regulatory role for Jak2 in thrombopoiesis

(2014) S. C. Meyer et al.   BLOOD

Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach

(2013) Richard S Hotchkiss et al.   LANCET INFECTIOUS DISEASES

Closing the Gap: Increases in Life Expectancy among Treated HIV-Positive Individuals in the United States and Canada

(2013) Hasina Samji et al.   PLoS One

Drotrecogin Alfa (Activated) in Adults with Septic Shock

(2012) V. Marco Ranieri et al.   NEW ENGLAND JOURNAL OF MEDICINE

Janus kinases in immune cell signaling

(2009) Kamran Ghoreschi et al.   IMMUNOLOGICAL REVIEWS

SARS coronavirus entry into host cells through a novel clathrin- and caveolae-independent endocytic pathway

(2008) Hongliang Wang et al.   CELL RESEARCH